Intra-Class Correlation Coefficient Ignorable Clustered Randomized Trials for Detecting Treatment Effect Heterogeneity
检测处理效应异质性时可忽略组内相关系数的整群随机试验
Accurately estimating the intra-class correlation coefficient (ICC) is crucial for adequately powering clustered randomized trials (CRTs). Challenges arise due to limited prior data on the specific outcome within the target population, making accurate ICC estimation difficult. Furthermore, ICC can vary significantly across studies, even for the same outcome, influenced by factors like study design, participant characteristics, and the specific intervention. Power…