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A Decision Theoretic Perspective on Artificial Superintelligence: Coping with Missing Data Problems in Prediction and Treatment Choice

人工超级智能的决策理论视角:预测与处理选择中的缺失数据问题

Enormous attention and resources are being devoted to the quest for artificial general intelligence and, even more ambitiously, artificial superintelligence. We wonder about the implications for methodological research that aims to help decision makers cope with what econometricians call identification problems, inferential problems in empirical research that do not diminish as sample size grows. Of particular concern are missing data problems in prediction and treatment…

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Coping with Inductive Risk When Theories are Underdetermined: Decision Making with Partial Identification

理论欠决定时应对归纳风险:部分识别下的决策

Controversy about the significance of underdetermination of theories persists in the philosophy and conduct of science. The issue has practical import when research is used to inform decision making, because scientific uncertainty yields inductive risk. Seeking to enhance communication between philosophers and researchers who study public policy, this paper describes econometric analysis of partial identification and its use in welfare-economic policy analysis. Study of…

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Prediction with Differential Covariate Classification: Illustrated by Covariate Classification in Medical Risk Assessment

协变量分类差异下的预测:医疗风险评估中的例证

A common practice in evidence-based decision-making uses estimates of conditional probabilities P(y|x) obtained from research studies to predict outcomes y on the basis of observed covariates x. Given this information, decisions are then based on the predicted outcomes. Researchers commonly assume that the predictors used in the generation of the evidence are the same as those used in applying the evidence: i.e., the meaning of x in the two circumstances is the same. This…

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Comprehensive OOS Evaluation of Predictive Algorithms with Statistical Decision Theory

基于统计决策理论的预测算法全面样本外评价

We argue that comprehensive out-of-sample (OOS) evaluation using statistical decision theory (SDT) should replace the current practice of K-fold and Common Task Framework validation in machine learning (ML) research on prediction. SDT provides a formal frequentist framework for performing comprehensive OOS evaluation across all possible (1) training samples, (2) populations that may generate training data, and (3) populations of prediction interest. Regarding feature (3), we…

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Using Ordinal Voting to Compare the Utilitarian Welfare of a Status Quo and A Proposed Policy: A Simple Nonparametric Analysis

利用序数投票比较现状与拟议政策的功利主义福利

The relationship of policy choice by majority voting and by maximization of utilitarian welfare has long been discussed. I consider choice between a status quo and a proposed policy when persons have interpersonally comparable cardinal utilities taking values in a bounded interval, voting is compulsory, and each person votes for a policy that maximizes utility. I show that knowledge of the attained status quo welfare and the voting outcome yields an informative bound on…

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Using Total Margin of Error to Account for Non-Sampling Error in Election Polls: The Case of Nonresponse

用总误差幅度衡量选举民调的非抽样误差:无应答情形

The potential impact of non-sampling errors on election polls is well known, but measurement has focused on the margin of sampling error. Survey statisticians have long recommended measurement of total survey error by mean square error (MSE), which jointly measures sampling and non-sampling errors. We think it reasonable to use the square root of maximum MSE to measure the total margin of error (TME). Measurement of TME should encompass both sampling error and all forms of…

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Identification and Statistical Decision Theory

识别与统计决策理论

Econometricians have usefully separated study of estimation into identification and statistical components. Identification analysis, which assumes knowledge of the probability distribution generating observable data, places an upper bound on what may be learned about population parameters of interest with finite sample data. Yet Wald's statistical decision theory studies decision making with sample data without reference to identification, indeed without reference to…

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Statistical Decision Theory Respecting Stochastic Dominance

尊重随机占优的统计决策理论

The statistical decision theory pioneered by Wald (1950) has used state-dependent mean loss (risk) to measure the performance of statistical decision functions across potential samples. We think it evident that evaluation of performance should respect stochastic dominance, but we do not see a compelling reason to focus exclusively on mean loss. We think it instructive to also measure performance by other functionals that respect stochastic dominance, such as quantiles of the…

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Using Limited Trial Evidence to Credibly Choose Treatment Dosage when Efficacy and Adverse Effects Weakly Increase with Dose

疗效与不良反应随剂量弱增时,如何利用有限试验证据选择剂量

In medical treatment and elsewhere, it has become standard to base treatment intensity (dosage) on evidence in randomized trials. Yet it has been rare to study how outcomes vary with dosage. In trials to obtain drug approval, the norm has been to specify some dose of a new drug and compare it with an established therapy or placebo. Design-based trial analysis views each trial arm as qualitatively different, but it may be highly credible to assume that efficacy and adverse…

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Partial Identification of Personalized Treatment Response with Trial-reported Analyses of Binary Subgroups

仅凭试验报告的二元亚组分析,部分识别个体化治疗反应

Medical journals have adhered to a reporting practice that seriously limits the usefulness of published trial findings. Medical decision makers commonly observe many patient covariates and seek to use this information to personalize treatment choices. Yet standard summaries of trial findings only partition subjects into broad subgroups, typically into binary categories. Given this reporting practice, we study the problem of inference on long mean treatment outcomes…

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Inference with Imputed Data: The Allure of Making Stuff Up

使用插补数据推断:编造数值的诱惑

Incomplete observability of data generates an identification problem. There is no panacea for missing data. What one can learn about a population parameter depends on the assumptions one finds credible to maintain. The credibility of assumptions varies with the empirical setting. No specific assumptions can provide a realistic general solution to the problem of inference with missing data. Yet Rubin has promoted random multiple imputation (RMI) as a general way to deal with…

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Minimax-Regret Climate Policy with Deep Uncertainty in Climate Modeling and Intergenerational Discounting

气候模型与代际贴现深度不确定性下的最小最大遗憾气候政策

Integrated assessment models have become the primary tools for comparing climate policies that seek to reduce greenhouse gas emissions. Policy comparisons have often been performed by considering a planner who seeks to make optimal trade-offs between the costs of carbon abatement and the economic damages from climate change. The planning problem has been formalized as one of optimal control, the objective being to minimize the total costs of abatement and damages over a time…

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Probabilistic Prediction for Binary Treatment Choice: with focus on personalized medicine

二元治疗选择中的概率预测:聚焦个体化医疗

This paper extends my research applying statistical decision theory to treatment choice with sample data, using maximum regret to evaluate the performance of treatment rules. The specific new contribution is to study as-if optimization using estimates of illness probabilities in clinical choice between surveillance and aggressive treatment. Beyond its specifics, the paper sends a broad message. Statisticians and computer scientists have addressed conditional prediction for…

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