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对假设进行压力测试：因果推断中的贝叶斯敏感性分析指南AI 解读

While observational data are routinely used to estimate causal effects of biomedical treatments, doing so requires special methods to adjust for observed confounding. These methods invariably rely on untestable statistical and causal identification assumptions. When these assumptions do not hold, sensitivity analysis methods can be used to characterize how different violations may change our inferences. The Bayesian approach to sensitivity analyses in causal inference has…

通过因子暴露映射对高维营养数据开展贝叶斯非参数因果推断AI 解读

Diet plays a crucial role in health, and understanding the causal effects of dietary patterns is essential for informing public health policy and personalized nutrition strategies. However, causal inference in nutritional epidemiology faces several challenges: (i) high-dimensional and correlated food/nutrient intake data induce massive treatment levels; (ii) nutritional studies are interested in latent dietary patterns rather than single food items; and (iii) the goal is to…

存在溢出效应时惩罚合成控制估计的贝叶斯收缩先验AI 解读

Synthetic control (SC) methods are widely used to estimate the effects of policy interventions, especially those targeting specific geographic regions, referred to as units. These methods construct a weighted combination of untreated units, forming a "synthetic" control that approximates the counterfactual outcomes of the treated unit had the intervention not occurred. Although neighboring areas are often selected as controls due to their similarity in observed and…

具有信息性处理时点的因果效应估计AI 解读

Epidemiological studies are often concerned with estimating causal effects of a sequence of treatment decisions on survival outcomes. In many settings, treatment decisions do not occur at fixed, pre-specified followup times. Rather, timing varies across subjects in ways that may be informative of subsequent treatment decisions and potential outcomes. Awareness of the issue and its potential solutions is lacking in the literature, which motivate this work. Here, we formalize…

平行趋势违背下双重差分政策评估的贝叶斯敏感性分析AI 解读

Violations of the parallel trends assumption pose significant challenges for causal inference in difference-in-differences (DiD) studies, especially in policy evaluations where pre-treatment dynamics and external shocks may bias estimates. In this work, we propose a Bayesian DiD framework to allow us to estimate the effect of policies when parallel trends is violated. To address potential deviations from the parallel trends assumption, we introduce a formal sensitivity…

结局与协变量信息不完整时 HIV 照护留存的贝叶斯反事实预测AI 解读

Like many chronic diseases, human immunodeficiency virus (HIV) is managed over time at regular clinic visits. At each visit, patient features are assessed, treatments are prescribed, and a subsequent visit is scheduled. There is a need for data-driven methods for both predicting retention and recommending scheduling decisions that optimize retention. Prediction models can be useful for estimating retention rates across a range of scheduling options. However, training such…

causalBETA：事件时间结局的贝叶斯半参数因果推断 R 包AI 解读

Observational studies are often conducted to estimate causal effects of treatments or exposures on event-time outcomes. Since treatments are not randomized in observational studies, techniques from causal inference are required to adjust for confounding. Bayesian approaches to causal estimates are desirable because they provide 1) prior smoothing provides useful regularization of causal effect estimates, 2) flexible models that are robust to misspecification, 3) full…