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中介分析中复合零假设的最优检验AI 解读

The indirect effect of an exposure on an outcome through an intermediate variable can be identified by a product of two regression coefficients under certain causal and regression modeling assumptions. In this context, the null hypothesis of no indirect effect is a composite null hypothesis, as the null holds if either regression coefficient is zero. A consequence is that traditional hypothesis tests are severely underpowered near the origin (i.e., when both coefficients are…

集合值政策学习AI 解读

Conventional treatment policies map patient covariates to a single recommended intervention in order to maximize expected clinical outcomes. Although a rich body of causal inference methods has been developed to estimate such policies, point-valued recommendations can be highly sensitive to estimation uncertainty, model specification, and finite-sample variability, while typically providing little guidance about how confident one should be in the recommended action. In this…

随机因果有向无环图的拓扑排序判据AI 解读

Random directed acyclic graphs (DAGs) based on imposing an order on Erdős-Rényi and scale free random graphs are widely used for evaluating causal discovery algorithms. We show that in such DAGs, the set of nodes reachable via open paths, termed relatives, increases monotonically along the causal order. We assess the prevalence of this pattern numerically, and demonstrate that it can be exploited for causal order recovery via sorting by the estimated number of relatives. We…

约束下的政策学习：最大化主要结果并控制不良事件AI 解读

A medical policy aims to support decision-making by mapping patient characteristics to individualized treatment recommendations. Standard approaches typically optimize a single outcome criterion. For example, recommending treatment according to the sign of the Conditional Average Treatment Effect (CATE) maximizes the policy "value" by exploiting treatment effect heterogeneity. This point of view shifts policy learning towards the challenge of learning a reliable CATE…

加性噪声模型中寻找因果顺序的尺度不变排序准则AI 解读

Additive Noise Models (ANMs) are a common model class for causal discovery from observational data and are often used to generate synthetic data for causal discovery benchmarking. Specifying an ANM requires choosing all parameters, including those not fixed by explicit assumptions. Reisach et al. (2021) show that sorting variables by increasing variance often yields an ordering close to a causal order and introduce var-sortability to quantify this alignment. Since increasing…

无需正值性假设的观察数据政策学习AI 解读

Policy learning utilizing observational data is pivotal across various domains, with the objective of learning the optimal treatment assignment policy while adhering to specific constraints such as fairness, budget, and simplicity. This study introduces a novel positivity-free (stochastic) policy learning framework designed to address the challenges posed by the impracticality of the positivity assumption in real-world scenarios. This framework leverages incremental…

边际结构模型中的自动化目标贝叶斯与目标最小损失估计推断AI 解读

Two of the principle tasks of causal inference are to define and estimate the effect of a treatment on an outcome of interest. Formally, such treatment effects are defined as a possibly functional summary of the data generating distribution, and are referred to as target parameters. Estimation of the target parameter can be difficult, especially when it is high-dimensional. Marginal Structural Models (MSMs) provide a way to summarize such target parameters in terms of a…

情境多臂老虎机实验后的统计推断AI 解读

Contextual bandit algorithms are increasingly replacing non-adaptive A/B tests in e-commerce, healthcare, and policymaking because they can both improve outcomes for study participants and increase the chance of identifying good or even best policies. To support credible inference on novel interventions at the end of the study, nonetheless, we still want to construct valid confidence intervals on average treatment effects, subgroup effects, or value of new policies. The…