Causal Effect Estimation on Restricted Mean Survival Time in Case-Cohort Studies via a Matching Design
病例队列研究中基于匹配设计的限制平均生存时间因果效应估计
In large observational studies, the case-cohort design is commonly used to reduce the cost associated with covariate measurement. For survival outcomes, literature has suggested that the restricted mean survival time (RMST) be a more appropriate marginal causal effect measure than the hazard ratio. In this paper, we develop a marginal causal effect estimation method for RMST difference under the stratified case-cohort design. We adjust for measured confounders using an…