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分类依据与纠错

AI 根据所提供的论文材料归类:摘要直接讨论处理效应的跨人群迁移、因果识别及混杂控制。

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代码、数据与补充材料

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关注这篇论文的作者
Issa J. Dahabreh
Sarah E. Robertson

在相对效应可迁移假设下识别新目标人群的处理效应

研究问题
如果试验中的条件风险比或均值比能够迁移到目标人群,如何识别该人群的边际因果效应,这与差值效应迁移有何关系?
方法与思路
作者以条件相对效应的可迁移性建立识别结果,并对目标人群使用多种处理的情形加入部分可交换性假设,提出可实现的估计量。
材料陈述的贡献
摘要称,相对效应与差值效应的可迁移性通常不兼容,并给出不同目标处理配置及不同协变量集合下的识别与估计结果。
阅读关注点
应核对可迁移性和部分可交换性的精确定义、识别所需的数据与支持集,以及迁移协变量和混杂控制协变量如何区分。
阅读边界
这是 arXiv 预印本,同行评审或接收状态未经核验;摘要未完整列出识别条件,也未说明估计量的具体形式及推断性质。

原文摘要

Epidemiologists and applied statisticians often believe that relative effect measures conditional on covariates, such as risk ratios and mean ratios, are ``transportable'' across populations. Here, we examine the identification of causal effects in a target population using an assumption that conditional relative effect measures (e.g., conditional risk ratios or mean ratios) are transportable from a trial to the target population. We show that transportability for relative effect measures is largely incompatible with transportability for difference effect measures, unless the treatment has no effect on average or one is willing to make even stronger transportability assumptions, which imply the transportability of both relative and difference effect measures. We then describe how marginal causal estimands in a target population can be identified under the assumption of transportability of relative effect measures, when we are interested in the effectiveness of a new experimental treatment in a target population where the only treatment in use is the control treatment evaluated in the trial. We extend these results to consider cases where the control treatment evaluated in the trial is only one of the treatments in use in the target population, under an additional partial exchangeability assumption in the target population (i.e., a partial assumption of no unmeasured confounding in the target population). We also develop identification results that allow for the covariates needed for transportability of relative effect measures to be only a small subset of the covariates needed to control confounding in the target population. Last, we propose estimators that can be easily implemented in standard statistical software.

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