Causal Survival Forests with Negative Controls
结合负向控制的因果生存森林AI 解读 ↓
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结合负向控制的因果生存森林AI 解读 ↓
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We study heterogeneous treatment-effect (HTE) estimation in observational survival studies commonly associated with both censored outcomes and unmeasured confounding. We integrate causal survival forests (CSF) with negative controls (NC) from proximal causal inference and introduce Negative Control Causal Survival Forests (NC-CSF), a flexible nonparametric HTE learner for survival analysis. Our approach uses a loss that incorporates proxy variables and Neyman orthogonalization to train the random forest, thereby mitigating bias from unobserved confounding and gaining robustness to nuisance estimation. Through extensive simulations spanning varying levels of confounding, proxy relevance, and censoring mechanisms, we demonstrate that NC-CSF substantially reduces bias and estimation error relative to existing baselines. We further demonstrate the practical utility of our method on various clinical datasets, where it confirms several existing findings and also reveals new interpretable patterns of treatment-effect heterogeneity. To facilitate practical use, we provide an end-to-end Python implementation of NC-CSF that carefully handles implementation details such as nuisance estimation and clipping.
条件影响函数
There are many nonparametric objects of interest that are functionals of a conditional distribution, such as average treatment effects conditional on a low-dimensional set of covariates. We define a conditional influence function (CIF) as the Gateaux derivative of a conditional parameter with respect to perturbations of the conditional law of a single observation given the conditioning variable. CIFs generalize classical influence functions and can be used to (i) construct…
图分割贝叶斯因果森林:空间异质性处理效应估计
In spatial observational studies, treatment assignment and outcomes often exhibit spatial dependence patterns, and treatment effects may vary across space and subpopulations due to both measured and unmeasured spatially structured confounders. Accounting for spatial dependence while estimating heterogeneous treatment effects (HTEs) is a central task in spatial causal inference. Causal Bayesian additive regression tree methods are popular nonparametric methods for modeling…
主分层下异质性处理效应的双重交叉拟合去偏机器学习
Principal stratification provides a foundational framework for causal inference with intermediate outcomes by defining causal effects within subpopulations, yet existing work has largely focused on average effects across strata rather than treatment effect heterogeneity within strata. Such within-stratum heterogeneity informs individualized treatment decisions but the associated methods are sparse. We address this gap by studying the identification and estimation of the…
利用双重机器学习估计直接与间接分位数处理效应
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异质环境下的不变量分位数回归
In this paper, we propose an invariant quantile regression (IQR) framework specifically designed for multi-environment datasets, which captures the invariance across different environments. This framework is closely related to transfer learning, causal inference, and fair machine learning, and is motivated by scenarios in which the conditional probability of the response given covariates varies, while certain key variables remain invariant. This perspective differs notably…
条件平均处理效应函数下水平集概率的非参数推断
The average treatment effect can obscure important heterogeneity when individuals respond differently to a treatment. While the conditional average treatment effect (CATE) function captures such heterogeneity, it is difficult to communicate when it depends on many covariates. Sublevels sets of a multivariate CATE function are equally complicated objects, but the probability of a sublevel set of a CATE function is a single number with a simple interpretation as the proportion…