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本页整理公开书目信息,不生成学术质量评分。AI 解读根据题名及所注明的摘要或原文片段生成,未完成全文核验,可能有误;具体假设、证明与结论请核对原文。摘要保留来源文本,未经模型改写。

DOI 首次登记不等于接收或发表日期。部分更正、评论等条目没有独立摘要;缺少可靠材料时保留待补状态。

本页为预印本版本;arXiv 收录、作者填写的期刊信息以及作者既有发表经历,都不单独证明本篇已接收。作者发表记录按 OpenAlex 身份与完整姓名、本站覆盖期刊 ISSN 及正式卷期核对,只展示已核实例,档案仍可能误合并。

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关注作者按书目中的完整姓名匹配,同名和姓名变体需人工辨别。相关论文先按共享细分方向和具体方法排列,再参考通用方法与发表日期。

分类依据与纠错

AI 根据所提供的论文材料归类:摘要明确以准实验框架估计医疗观察数据中的处理效应,因此归入因果推断。

反馈分类问题

正在核对关联版本…

代码、数据与补充材料

正在核对对应版本的资源…

关注这篇论文的作者
Tomoru Nakayama
Yuji Kawamata
Akihiro Toyoda
Akira Imakura
Rina Kagawa
Masaru Sanuki
Ryoya Tsunoda
Kunihiro Yamagata
Tetsuya Sakurai
Yukihiko Okada

基于有限医学检测与用药数据的数据协作因果推断

研究问题
医疗机构能否通过共享降维后的中间表示开展协作因果分析,在减少原始数据共享的同时接近集中分析的表现?
方法与思路
作者用单一机构医疗数据模拟 IID 与非 IID 分布式环境,应用数据协作准实验框架,并提出新的中间表示生成方法。
材料陈述的贡献
摘要称,协作分析在多项准确性指标上优于单独分析并接近集中分析,新表示方法尤其改善了非 IID 环境下的表现。
阅读关注点
应核对准实验的识别依据、中间表示保留哪些信息,以及分布式划分方式、准确性指标和隐私保护的具体论证。
阅读边界
这是 arXiv 预印本,不能据此认定已同行评审或获期刊接收;单机构模拟不能直接代表真实跨机构表现,摘要未说明隐私保证。

原文摘要

Observational studies enable causal inferences when randomized controlled trials (RCTs) are not feasible. However, integrating sensitive medical data across multiple institutions introduces significant privacy challenges. The data collaboration quasi-experiment (DC-QE) framework addresses these concerns by sharing "intermediate representations" -- dimensionality-reduced data derived from raw data -- instead of the raw data. While the DC-QE can estimate treatment effects, its application to medical data remains unexplored. This study applied the DC-QE framework to medical data from a single institution to simulate distributed data environments under independent and identically distributed (IID) and non-IID conditions. We propose a novel method for generating intermediate representations within the DC-QE framework. Experimental results demonstrated that DC-QE consistently outperformed individual analyses across various accuracy metrics, closely approximating the performance of centralized analysis. The proposed method further improved performance, particularly under non-IID conditions. These outcomes highlight the potential of the DC-QE framework as a robust approach for privacy-preserving causal inferences in healthcare. Broader adoption of this framework and increased use of intermediate representations could grant researchers access to larger, more diverse datasets while safeguarding patient confidentiality. This approach may ultimately aid in identifying previously unrecognized causal relationships, support drug repurposing efforts, and enhance therapeutic interventions for rare diseases.

笔记与分组
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