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AI 根据所提供的论文材料归类:摘要明确以每日住院与 ICU 占床时间序列拟合随机动态模型,分类依据是时间序列方法而非应用属于宏观经济。

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关注这篇论文的作者
Achal Awasthi
Volodymyr M. Minin
Jenny Huang
Daniel Chow
Jason Xu

新冠疫情期间利用含噪住院时间序列拟合 ICU 占床随机模型

研究问题
缺少个体住院记录时,如何从每日医院与 ICU 占床数推断患者流入和退出速率,并解释 ICU 占床动态的变化?
方法与思路
作者用移入—消亡过程刻画 ICU 占床波动,在似然框架中允许速率依赖医院占床与检测阳性率,并开展模拟、模型选择和数据验证。
材料陈述的贡献
摘要称模型能处理含噪占床序列,应用识别出住院与阳性率的重要性,并以匿名个体住院数据验证人均 ICU 停留时间估计。
阅读关注点
应核对占床总量对流入和退出率的识别、协变量作用形式、噪声处理与模型选择,以及个体记录验证的具体指标。
阅读边界
这是 arXiv 预印本,同行评审及期刊接收未获核实;摘要未说明参数识别条件或验证误差,协变量重要性不能直接解释为因果作用。

原文摘要

Intensive care occupancy is an important indicator of health care stress that has been used to guide policy decisions during the COVID-19 pandemic. Toward reliable decision-making as a pandemic progresses, estimating the rates at which patients are admitted to and discharged from hospitals and intensive care units (ICUs) is crucial. Since individual-level hospital data are rarely available to modelers in each geographic locality of interest, it is important to develop tools for inferring these rates from publicly available daily numbers of hospital and ICU beds occupied. We develop such an estimation approach based on an immigration-death process that models fluctuations of ICU occupancy. Our flexible framework allows for immigration and death rates to depend on covariates, such as hospital bed occupancy and daily SARS-CoV-2 test positivity rate, which may drive changes in hospital ICU operations. We demonstrate via simulation studies that the proposed method performs well on noisy time series data and apply our statistical framework to hospitalization data from the University of California, Irvine (UCI) Health and Orange County, California. By introducing a likelihood-based framework where immigration and death rates can vary with covariates, we find, through rigorous model selection, that hospitalization and positivity rates are crucial covariates for modeling ICU stay dynamics and validate our per-patient ICU stay estimates using anonymized patient-level UCI hospital data.

笔记与分组