Controllable Generative Sandbox for Causal Inference
用于因果推断的可控生成式沙盒AI 解读 ↓
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用于因果推断的可控生成式沙盒AI 解读 ↓
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Method validation and study design in causal inference rely on synthetic data with known counterfactuals. Existing simulators trade off distributional realism, the ability to capture mixed-type and multimodal tabular data, against causal controllability, including explicit control over overlap, unmeasured confounding, and treatment effect heterogeneity. We introduce CausalMix, a variational generative framework that closes this gap by coupling a mixture of Gaussian latent priors with data-type-specific decoders for continuous, binary, and categorical variables. The model incorporates explicit causal controls: an overlap regularizer shaping propensity-score distributions, alongside direct parameterizations of confounding strength and effect heterogeneity. This unified objective preserves fidelity to the observed data while enabling factorial manipulation of causal mechanisms, allowing overlap, confounding strength, and treatment effect heterogeneity to be varied independently at design time. Across benchmarks, CausalMix achieves state-of-the-art distributional metrics on mixed-type tables while providing stable, fine-grained causal control. We demonstrate practical utility in a comparative safety study of metastatic castration-resistant prostate cancer treatments, using CausalMix to compare estimators under calibrated data-generating processes, tune hyperparameters, and conduct simulation-based power analyses under targeted treatment effect heterogeneity scenarios.
IV-LASSO 的工具变量字典与惩罚选择
Estimating the first stage of an instrumental variables (IV) model with the least absolute shrinkage and selection operator (LASSO) requires choosing a dictionary of technical instruments and a penalty level. First-order asymptotic theory offers no guidance on these choices, as any consistent implementation yields a structural parameter estimator with the same limiting distribution. In finite samples, however, these choices can have a substantial impact on the resulting…
结果选择下用于目标因果推断的协作表征
Estimating causal effects with missing outcomes requires learning outcome, exposure, and selection models. Flexible propensity learners can predict treatment or missingness well while worsening target estimation by emphasizing instruments, weak-overlap regions, or variation unrelated to outcome-regression bias. We propose a collaborative representation-based targeted learning method for recovered average treatment effects under outcome selection. The method learns…
稀疏依赖下二元配置概率的对抗估计
We consider the problem of estimating binary configuration probabilities, which is common in operations management applications, including product bundling, advertising, etc. Existing approaches typically model each assortment as a category and apply multinomial models to estimate the choice probabilities; while computationally convenient, these methods do not exploit independence structures in the joint distribution and may therefore be statistically inefficient when the…
基于残差化 Walsh–Hadamard 得分的异质析因效应修饰因子去偏与同时推断
In factorial randomized experiments with $K$ binary treatment components, we study which baseline covariates modify component main effects and interactions. We define effect-modifier cells $(j,S)$, $j\in[p]$ and $\emptyset\neq S\subseteq[K]$, through the coefficients $θ^\ast_{jS}$ of population linear projections of conditional Walsh--Hadamard contrasts $τ_{S}$ onto standardized covariates. Using baseline-robust direct scores, we develop frequentist inference for all $p(2^K-1)$…
协变量漂移下外部有效性的简单稳健性度量
This paper studies the robustness of estimated policy effects to changes in the distribution of covariates, a key determinant of the external validity of (quasi)experimental results. I propose a novel robustness metric δ ∗ which measures the smallest covariate shift needed to invalidate an empirical claim about the policy effect (e.g., AT E > 0). I estimate δ ∗ via de-biased GMM, achieving a parametric rate of convergence while accommodating machine-learning estimators of…
基于贝叶斯机器学习的决策论亚组发现
We consider the problem of identifying promising subpopulations in terms of treatment effectiveness or treatment effect heterogeneity, from a Bayesian decision theoretic perspective. We first show that a straight-forward application of Bayesian decision theory to subgroup detection leads to a counter-intuitive risk-seeking (RS) behavior. Motivated by this observation, we introduce the Bayesian Risk-Aware Inference and Detection of Subgroups (BRAIDS) utility and use it to…