Counterfactual Cocycles: A Framework for Robust and Coherent Counterfactual Transports
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Estimating joint distributions (a.k.a. couplings) over counterfactual outcomes is central to personalized decision-making and treatment risk assessment. Two emergent frameworks with identifiability guarantees are: (i) bijective structural causal models (SCMs), which are flexible but brittle to mis-specified latent noise; and (ii) optimal-transport (OT) methods, which avoid latent noise assumptions but can produce incoherent counterfactual transports which fail to identify higher-order couplings. In this work, we bridge the gap with \emph{counterfactual cocycles}: a framework for counterfactual transports that use algebraic structure to provide coherence and identifiability guarantees. Every counterfactual cocycle corresponds to an equivalence class of SCMs, however the cocycle is invariant to the latent noise distribution, enabling us to sidestep various mis-specification problems. We characterize the structure of all identifiable counterfactual cocycles; propose flexible model parameterizations; introduce a novel cocycle estimator that avoids any distributional assumptions; and derive mis-specification robustness properties of the resulting counterfactual inference method. We demonstrate state-of-the-art performance and noise-robustness of counterfactual cocycles across synthetic benchmarks and a 401(k) eligibility study.
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We develop a semiparametric continuous time inferential framework for testing cumulative treatment effects, including both immediate and carryover effects. The latent state process is modeled by an ordinary differential equation (ODE) whose drift depends on state and treatment, while the observed data are noisy measurements of this latent state at irregular, multi resolution time points. We define the average treatment effect (ATE) as the difference of expected cumulative…
We study inference for continuous linear functionals of solutions to ill-posed inverse problems, including Euclidean parameters arising in nonparametric instrumental variables, proximal causal inference, and shadow-variable models. Although pointwise root-$n$ inference is possible under standard conditions, we show that this need not translate into locally reliable inference. Under a model imposing only minimal regularity conditions, the target is Hellinger discontinuous…
Motivation: Mediation analysis is an important tool for elucidating causal mechanisms in biomedical research and has recently gained increasing attention in microbiome studies. Motivated by a microbiome study of acute myeloid leukemia (AML) patients, we investigate whether the effect of induction chemotherapy intensity on infection status is mediated through gut microbial taxa. This problem poses substantial methodological challenges due to the high dimensionality, zero…
观测因果推断中不完全识别下的相对偏差
To conduct causal inference in observational settings, researchers must rely on certain identifying assumptions. In practice, these assumptions are unlikely to hold exactly. This paper considers the bias of selection-on-observables, instrumental variables, and proximal inference estimates under violations of their identifying assumptions. We develop bias expressions for IV and proximal inference that show how violations of their respective assumptions are amplified by any…
Two frequent approaches for identifying structural VARs are external instruments, which carry economic content but are often weak, and non-Gaussianity of the shocks, which provides statistical identification but carries no economic meaning. We combine the two strategies in a single generalized method of moments framework. This hybrid approach point-identifies the target shocks while also identifying the non-target shocks up to sign and ordering. Under suitable rank…