Bayesian change-plane regression
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Change-plane regression represents treatment effect heterogeneity through an interpretable rule that assigns patients to two groups according to whether a linear score of baseline covariates crosses a threshold. Although easy to communicate, likelihood-based inference for the hard threshold is nonregular, invalidating standard large-sample approximations. We develop a Bayesian framework that replaces the sharp indicator with a smooth probit gate at a declared smoothing scale and treats the smoothed subgroup rule as the reported estimand. At a fixed smoothing scale, the posterior satisfies a misspecified Bernstein--von Mises theorem centered at the smoothed rule. Under a vanishing smoothing schedule, the posterior learns the boundary faster than the parametric rate, while within an explicit schedule window the regression block and treatment-effect contrast satisfy a Bernstein--von Mises theorem centered at the hard-threshold values with known-subgroup oracle efficiency. Thus, effect inference pays no first-order price for regularization. A decision-theoretic reporting protocol with consistency guarantees separates evidence of heterogeneity from reporting a boundary. Computation uses latent-variable augmentation, a great-circle elliptical slice sampler, and a normalized horseshoe prior. Simulations and an application to the PREMIER trial illustrate the method.
基于贝叶斯机器学习的决策论亚组发现
We consider the problem of identifying promising subpopulations in terms of treatment effectiveness or treatment effect heterogeneity, from a Bayesian decision theoretic perspective. We first show that a straight-forward application of Bayesian decision theory to subgroup detection leads to a counter-intuitive risk-seeking (RS) behavior. Motivated by this observation, we introduce the Bayesian Risk-Aware Inference and Detection of Subgroups (BRAIDS) utility and use it to…
交错双重差分中的部分同质性
In staggered difference-in-differences (DiD) designs, units enter treatment at different calendar times, so the treatment effect is not a single number but a set of Cohort-Average Treatment effects on the Treated (CATTs), one per cohort-time cell. Estimating every CATT as its own parameter, as the standard fully flexible estimator does, is unbiased but inefficient when some of these effects are in fact equal, whereas pooling them all into a single two-way fixed effects…
事件时间结果因果亚组估计的贝叶斯层级自助框架
Causal estimation of treatment effects within prespecified subgroups, such as biomarker-defined strata, disease phenotypes, or demographic groups are often of clinical interest. Bayesian approaches are attractive for subgroup effect estimation because flexible priors can represent complex treatment heterogeneity and propagate posterior uncertainty. Frequentist methods for prespecified causal subgroup analysis with time-to-event outcomes are also available, including…
通过 Riesz 表示构建现代因果面板估计量的贝叶斯稳健性值
We develop a sensitivity-analysis workflow for causal panel estimators, covering synthetic difference-in-differences, matrix completion, fixed-effect imputation, and group-time average treatment effects. The workflow combines Riesz-representation omitted-variable-bias bounds with partial-$R^2$ robustness values and separates two reporting routes. Route A gives a direct sensitivity profile for additive or projected confounding summarized by outcome-side and Riesz-side partial…
ShrinkageTrees:用于生存分析与因果推断的贝叶斯树集成 R 包
ShrinkageTrees is an R package for Bayesian tree ensembles in survival analysis and causal inference. The package implements Bayesian additive regression tree models for right- and interval-censored survival outcomes within an accelerated failure time (AFT) framework, with optional decomposition into prognostic and treatment-effect components for causal inference. Two complementary forms of regularisation are available: regularisation of the tree structure, via…
PRCD-MAP:在因果发现中学习对不完美先验的信任程度
External priors of unknown reliability create a brittle trade-off in causal discovery: blind trust amplifies errors, blind rejection wastes signal. Real priors are also heterogeneously reliable -- physical laws are trustworthy, LLM-suggested edges are speculative -- yet existing methods either ignore priors or impose them through globally uniform trust. We propose PRCD-MAP, a soft prior-consumption layer that assigns per-edge trust to an imperfect prior and uses it to…