Meta-Analysis of Mid- p -Values: Some New Results based on the Convex Order
基于凸序的 mid-p 值元分析新结果AI 解读 ↓
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The mid-p-value is a proposed improvement on the ordinary p-value for the case where the test statistic is partially or completely discrete. In this case, the ordinary p-value is conservative, meaning that its null distribution is larger than a uniform distribution on the unit interval, in the usual stochastic order. The mid-p-value is not conservative. However, its null distribution is dominated by the uniform distribution in a different stochastic order, called the convex order. The property leads us to discover some new finite-sample and asymptotic bounds on functions of mid-p-values, which can be used to combine results from different hypothesis tests conservatively, yet more powerfully, using mid-p-values rather than p-values. Our methodology is demonstrated on real data from a cyber-security application.
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结合 model-X knockoffs 与 p 值的高维线性模型 FDR 控制
We propose a novel multiple testing methodology for controlling the false discovery rate (FDR) in high-dimensional linear models that integrates model-X knockoff techniques with debiased penalized regression estimators. At the foundation of our methodology, we construct and study two sets of naturally paired high-dimensional test statistics and the associated $p$-values for evaluating the same null hypotheses. The first set is shown to be asymptotically mutually independent,…