A Bayesian model for the optimal ordering of a collection of screens
一组筛查程序最优排序的贝叶斯模型AI 解读 ↓
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一组筛查程序最优排序的贝叶斯模型AI 解读 ↓
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Bergman & Gittins (1985) propose a screen design problem in which a collection of screens for therapeutic activity and toxicity of pharmaceutical compounds is to be sequenced. They describe conditions under which a natural ordering heuristic based on failure probability per unit cost for each screen is optimal. We propose a Bayesian model in which measures of activity and toxicity are given a joint prior density. The above conditions for optimality are satisfied for this model under simply stated conditions. A numerical study suggests that the heuristic performs well more generally.
Bayesian additive regression trees (BART) is a popular Bayesian ensemble model used in regression and classification analysis. Under this modeling framework, the regression function is approximated by an ensemble of decision trees, interpreted as weak learners. In this work, we propose a generalization of the BART model that has two main features: first, it automatically selects the number of decision trees using the given data; second, the model allows clusters of…
估计纵向因果剂量反应关系的贝叶斯框架
Existing causal methods for time-varying exposure and time-varying confounding focus on estimating the average causal effect of a time-varying binary treatment on an end-of-study outcome, offering limited tools for characterizing marginal causal dose-response relationships under continuous exposures. We propose a scalable, nonparametric Bayesian framework for estimating marginal longitudinal causal dose-response functions with repeated outcome measurements. Our approach…
内生性检验:一种基于矩的贝叶斯方法
A standard assumption in the Bayesian estimation of linear regression models is that the regressors are exogenous in the sense that they are uncorrelated with the model error term. In practice, however, this assumption can be invalid. In this article, using the exponentially tilted empirical likelihood (ETEL) framework, we develop a Bayes factor test for endogeneity that compares a base model that is correctly specified under exogeneity but misspecified under endogeneity…
凸正则化的谱依赖:右旋转不变设计下的基本极限
We study the fundamental limits of convex-regularized estimation in high-dimensional linear regression with right-rotationally invariant design matrices. We show that the asymptotic risks of convex-penalized least squares estimators are lower bounded by the risk of an approximate message passing algorithm known as Bayes VAMP, and we further characterize when the lower bound is attainable. As a technical ingredient in the proof of our lower bound theorem, we characterize the…
We study structural changes in multivariate time series by estimating and comparing stationary graphs of macroeconomic time series before and after an economic crisis, such as the Great Recession. Building on a latent time series framework called Orthogonally-rotated Univariate Time-series (OUT), we propose a shared-parameter framework-the spOUT autoregressive model (spOUTAR)-that jointly models two related multivariate time series and enables coherent Bayesian estimation of…
自适应实验中策略改进价值的推断
In this paper, we develop an asymptotically normal estimator for the value of policy improvement (VPI) under adaptively collected data. This value, which is defined as the gap between the value of the best treatment policy in a class and that of a baseline policy, gauges whether or not it is worth deploying a personalized treatment policy. Building an estimator for the VPI is naturally more difficult than estimating the value of a fixed policy. This is because, in addition…