Semiparametric Efficient Inference for the Probability of Necessary and Sufficient Causation
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Causal attribution, which aims to explain why events or behaviors occur, is crucial in causal inference and enhances our understanding of cause-and-effect relationships in scientific research. The probabilities of necessary causation (PN) and sufficient causation (PS) are two of the most common quantities for attribution in causal inference. While many works have explored the identification or bounds of PN and PS, efficient estimation remains unaddressed. To fill this gap, this paper focuses on obtaining semiparametric efficient estimators of PN and PS under two sets of identifiability assumptions: strong ignorability and monotonicity, and strong ignorability and conditional independence. We derive efficient influence functions and semiparametric efficiency bounds for PN and PS under the two sets of identifiability assumptions, respectively. Based on this, we propose efficient estimators for PN and PS, and show their large sample properties. Extensive simulations validate the superiority of our estimators compared to competing methods. We apply our methods to a real-world dataset to assess various risk factors affecting stroke.
连接局部与总体因果效应:近端工具变量方法
Instrumental variable (IV) methods address treatment endogeneity, but with non-compliance and heterogeneous treatment effects a binary instrument generally identifies the local average treatment effect (LATE) among compliers rather than the population average treatment effect (ATE). When treatment effects and compliance probabilities are heterogeneous and dependent through latent factors, the ATE need not be identified by IV variation alone. We develop a proximal…
MediEncoder:高维因果中介分析的非线性表示学习
Causal mediation analysis decomposes a treatment effect into indirect pathways through mediators and direct pathways not operating through them. Modern biomedical studies often involve high-dimensional covariates and mediators that are noisy proxies for lower-dimensional latent biological processes. Existing methods typically rely on sparsity, linear factor models, or ignore the connection among variables in the learned representations, which can be restrictive when…
通过张量补全推断序贯处理的因果效应
Marginal Structural Models (MSMs) are popular for causal inference of sequential treatments in longitudinal observational studies, which however are sensitive to model misspecification. To achieve flexible modeling, we envision the potential outcomes to form a three-dimensional tensor indexed by subject, time, and treatment regime and propose a tensorized history-restricted MSM (HRMSM). The semi-parametric tensor factor model allows us to leverage the underlying low-rank…
低秩模型的统计推断
This paper studies inference in linear models with a high-dimensional parameter matrix that can be well approximated by a “spiked low-rank matrix.” A spiked low-rank matrix has rank that grows slowly compared to its dimensions and nonzero singular values that diverge to infinity. We show that this framework covers a broad class of models of latent variables, which can accommodate matrix completion problems, factor models, varying coefficient models and heterogeneous…
低秩模型的统计推断
This paper studies inference in linear models with a high-dimensional parameter matrix that can be well-approximated by a ``spiked low-rank matrix.'' A spiked low-rank matrix has rank that grows slowly compared to its dimensions and nonzero singular values that diverge to infinity. We show that this framework covers a broad class of models of latent-variables which can accommodate matrix completion problems, factor models, varying coefficient models, and heterogeneous…
处理效应估计:中国2008年经济刺激计划案例
Researchers often face the challenge of estimating the counterfactuals to evaluate the treatment effects. Hsiao et al. (2012) propose a method that offers more flexibilities by allowing the influence of the unobservable latent factors to vary cross-section. This paper relaxes the linear conditional mean assumption in their method by extending it to a semi-parametric setting. The asymptotic distribution properties of the average treatment effect estimator is derived and…