Best Invariant Unbiased Estimators for the Mean Squared Error of Variance Component Estimators
方差分量估计量均方误差的最佳不变无偏估计AI 解读 ↓
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An unbiased estimator is derived for the mean squared error of any unbiased or biased estimator that is expressible as a linear combination of independent sums of squares. Further, it is shown that, for the classical balanced variance component models, this estimator is the best invariant unbiased estimator for the variance of the ANOVA estimator and for the mean squared error of the nonnegative minimum biased estimator. As an example, the balanced one-way classification model with random effects is considered.
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In placebo-controlled randomized clinical trials (RCTs), the placebo response significantly modifies treatment effects and diminishes the intention-to-treat (ITT) treatment effect, $Δ_{ITT}$. This study presents a novel two-stage framework for estimating the standardized causal treatment effect, $Δ_{STD}$, among the ITT population, under the assumption that their placebo responses are similar to the levels of self-administering medication at home. The first stage employs a…
Normality pre-tests on reduced-form innovations cannot detect whether two or more underlying structural shocks are Gaussian, and hence cannot detect a failure of identification in non-Gaussian SVARs. We propose a bootstrap-based approach that reveals such a failure. Under the null of valid identification and certain regularity conditions, the conditional bootstrap distribution of the maximum likelihood estimator of the impact matrix is asymptotically normal, so the…
Understanding associations between paired high-dimensional longitudinal datasets is a fundamental yet challenging problem arising across scientific domains, including longitudinal multi-omic studies. The difficulty stems from the complex, time-varying cross-covariance structure coupled with high dimensionality, which complicates both model formulation and statistical estimation for association discovery. To address these challenges, we propose a new framework called…