Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments
随机实验中通用机器学习发现的异质性处理效应:统计推断AI 解读 ↓
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随机实验中通用机器学习发现的异质性处理效应:统计推断AI 解读 ↓
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Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects under practical settings with many covariates and small sample size. In addition, the quantification of estimation uncertainty remains a challenge. We develop a general approach to statistical inference for heterogeneous treatment effects discovered by a generic ML algorithm. We apply the Neyman's repeated sampling framework to a common setting, in which researchers use an ML algorithm to estimate the conditional average treatment effect and then divide the sample into several groups based on the magnitude of the estimated effects. We show how to estimate the average treatment effect within each of these groups, and construct a valid confidence interval. In addition, we develop nonparametric tests of treatment effect homogeneity across groups, and rank-consistency of within-group average treatment effects. The validity of our methodology does not rely on the properties of ML algorithms because it is solely based on the randomization of treatment assignment and random sampling of units. Finally, we generalize our methodology to the cross-fitting procedure by accounting for the additional uncertainty induced by the random splitting of data.
条件影响函数
There are many nonparametric objects of interest that are functionals of a conditional distribution, such as average treatment effects conditional on a low-dimensional set of covariates. We define a conditional influence function (CIF) as the Gateaux derivative of a conditional parameter with respect to perturbations of the conditional law of a single observation given the conditioning variable. CIFs generalize classical influence functions and can be used to (i) construct…
图分割贝叶斯因果森林:空间异质性处理效应估计
In spatial observational studies, treatment assignment and outcomes often exhibit spatial dependence patterns, and treatment effects may vary across space and subpopulations due to both measured and unmeasured spatially structured confounders. Accounting for spatial dependence while estimating heterogeneous treatment effects (HTEs) is a central task in spatial causal inference. Causal Bayesian additive regression tree methods are popular nonparametric methods for modeling…
结合负向控制的因果生存森林
We study heterogeneous treatment-effect (HTE) estimation in observational survival studies commonly associated with both censored outcomes and unmeasured confounding. We integrate causal survival forests (CSF) with negative controls (NC) from proximal causal inference and introduce Negative Control Causal Survival Forests (NC-CSF), a flexible nonparametric HTE learner for survival analysis. Our approach uses a loss that incorporates proxy variables and Neyman…
主分层下异质性处理效应的双重交叉拟合去偏机器学习
Principal stratification provides a foundational framework for causal inference with intermediate outcomes by defining causal effects within subpopulations, yet existing work has largely focused on average effects across strata rather than treatment effect heterogeneity within strata. Such within-stratum heterogeneity informs individualized treatment decisions but the associated methods are sparse. We address this gap by studying the identification and estimation of the…
利用双重机器学习估计直接与间接分位数处理效应
We propose a framework to disentangle the quantile treatment effect of a binary treatment at a specific rank into an indirect quantile treatment effect that operates through a mediator and an unmediated direct quantile treatment effect. We establish identification results for these effects under the sequential ignorability assumption and propose double/debiased machine learning estimators, based on the efficient influence functions of the cumulative distribution functions of…
异质环境下的不变量分位数回归
In this paper, we propose an invariant quantile regression (IQR) framework specifically designed for multi-environment datasets, which captures the invariance across different environments. This framework is closely related to transfer learning, causal inference, and fair machine learning, and is motivated by scenarios in which the conditional probability of the response given covariates varies, while certain key variables remain invariant. This perspective differs notably…