Denoising Data with Measurement Error Using a Reproducing Kernel-based Diffusion Model
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基于再生核扩散模型的测量误差数据去噪AI 解读 ↓
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The ongoing technological revolution in measurement systems enables the acquisition of high-resolution samples in fields such as engineering, biology, and medicine. However, these observations are often subject to errors from measurement devices. Motivated by this challenge, we propose a denoising framework that employs diffusion models to generate denoised data whose distribution closely approximates the unobservable, error-free data, thereby permitting standard data analysis based on the denoised data. The key element of our framework is a novel Reproducing Kernel Hilbert Space-based method that trains the diffusion model with only error-contaminated data, admits a closed-form solution, and achieves a fast convergence rate in terms of estimation error. Furthermore, we verify the effectiveness of our method by deriving an upper bound on the Kullback--Leibler divergence between the distributions of the generated denoised data and the error-free data. A series of conducted simulations also verify the promising empirical performance of the proposed method compared to other state-of-the-art methods. To further illustrate the potential of this denoising framework in a real-world application, we apply it in a digital health context, showing how measurement error in continuous glucose monitors can influence conclusions drawn from a clinical trial on diabetes Mellitus disease.
We develop a semiparametric continuous time inferential framework for testing cumulative treatment effects, including both immediate and carryover effects. The latent state process is modeled by an ordinary differential equation (ODE) whose drift depends on state and treatment, while the observed data are noisy measurements of this latent state at irregular, multi resolution time points. We define the average treatment effect (ATE) as the difference of expected cumulative…
当处理发生溢出:时空因果效应估计的神经网络框架
Real-world public health policies are often enacted by local jurisdictions, but their effects can ripple through connected populations. For causal evaluation, this creates a difficult spatiotemporal problem: intermittent policy updates create path-level treatments, and because spillover depends on neighboring treatment paths along with the focal-unit's own history, controlling time-varying confounding requires high-dimensional, multimodal information from both sources. To…
时空干扰下用于实验的聚类切换设计
We consider experimentation in the presence of non-stationarity, inter-unit (spatial) interference, and carry-over effects (temporal interference), where we wish to estimate the global average treatment effect (GATE), the difference between average outcomes having exposed all units at all times to treatment or to control. We suppose spatial interference is described by a graph, where a unit's outcome depends on its neighborhood's treatments, and that temporal interference is…
RBF 核高斯过程最大似然估计的精确渐近理论
Gaussian processes (GPs) are widely used across machine learning, spatial statistics, time-series analysis, optimization, Bayesian statistics, and scientific applications. A central component of a GP model is its kernel, which is typically specified through a parametric family. Among the most widely used choices is the radial basis function (RBF), also known as the squared exponential or Gaussian kernel, owing to its simple form, smoothness, and flexibility. In practice, the…
ARMA 过程谱密度函数的分解
Quasi-periodic oscillations are characterized by fitting Lorentzian functions to a nonparametric estimate of the power spectral density, a two-step procedure that separates estimation from modeling and does not accommodate measurement error. We develop a parametric alternative based on autoregressive moving-average (ARMA) processes observed with measurement error. We derive an exact decomposition of the ARMA spectral density into real-valued components, one for each class of…
异质性高维分位数回归的全局推断
Quantile regression has received considerable attention in high dimensional methodology due to its robustness and ability to accommodate heteroskedasticity. Despite this attention, current inferential methods for high dimensional quantile regression have significant limitations---only testing significance, testing at a single quantile at a time, or assuming homoskedasticity. To generalize the inferences that can be drawn in high dimensional quantile regression, we introduce…