On protected estimation of an odds ratio model with missing binary exposure and confounders
二元暴露与混杂变量缺失下优势比模型的保护性估计AI 解读 ↓
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二元暴露与混杂变量缺失下优势比模型的保护性估计AI 解读 ↓
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We describe an estimator of the parameter indexing a model for the conditional odds ratio between a binary exposure and a binary outcome given a high-dimensional vector of confounders, when the exposure and a subset of the confounders are missing, not necessarily simultaneously, in a subsample. We argue that a recently proposed estimator restricted to complete-cases confers more protection to model misspecification than existing ones in the sense that the set of data laws under which it is consistent strictly contains each set of data laws under which each of the previous estimators are consistent.
高维稀疏组卷积平滑分位数回归
In many applications, covariates are naturally organized into groups, yet conventional group-selection methods often retain all variables within selected groups, failing to achieve within-group sparsity. To address this limitation, we propose an adaptive two-stage sparse-group selection procedure for high-dimensional quantile regression. The proposed method integrates convolution-smoothed quantile loss with $\ell_{2,0}$ and $\ell_0$ penalties to identify important groups and…
Bayesian additive regression trees (BART) is a popular Bayesian ensemble model used in regression and classification analysis. Under this modeling framework, the regression function is approximated by an ensemble of decision trees, interpreted as weak learners. In this work, we propose a generalization of the BART model that has two main features: first, it automatically selects the number of decision trees using the given data; second, the model allows clusters of…
高维线性模型中基于汇总统计量的遗传力估计的一致性
In Genome-Wide Association Studies (GWAS), heritability is defined as the fraction of variance of an outcome explained by a large number of genetic predictors in a high-dimensional polygenic linear model. This work studies the asymptotic properties of the most common estimator of heritability from summary statistics called linkage disequilibrium score (LDSC) regression, together with a simpler and closely related estimator called GWAS heritability (GWASH). These estimators…
The conditional average treatment effect (CATE) is frequently estimated in clinical studies to refute a homogeneous treatment effect hypothesis. Under this regime, all patients making up the population experience identical benefit from a given treatment relative to a comparator. Uncovering heterogeneous treatment effects through inference about the CATE, however, requires that covariates truly modifying the treatment effect be reliably collected at baseline. CATE-based…
凸正则化的谱依赖:右旋转不变设计下的基本极限
We study the fundamental limits of convex-regularized estimation in high-dimensional linear regression with right-rotationally invariant design matrices. We show that the asymptotic risks of convex-penalized least squares estimators are lower bounded by the risk of an approximate message passing algorithm known as Bayes VAMP, and we further characterize when the lower bound is attainable. As a technical ingredient in the proof of our lower bound theorem, we characterize the…
从图套索到原子范数:高维模式恢复
We study high-dimensional precision-matrix estimation with polyhedral atomic-norm penalties on the off-diagonal entries. This framework covers the graphical lasso, $\ell_\infty$-type penalties, SLOPE/OWL penalties, and penalties motivated by colored graphical models. We define the target pattern through the subdifferential face of the dual ball and derive sufficient conditions for exact pattern recovery from the sample covariance matrix. Our analysis introduces two geometric…