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关注这篇论文的作者
Gildas Mazo
Dimitris Karlis
Andrea Rau

复杂统计推断的随机化成对似然方法

研究问题
当完整似然难以计算时,如何进一步降低成对似然在高维数据中的估计成本,以及构造置信区间所需的计算负担?
方法与思路
作者在观测与变量对两个维度随机抽取似然求和项,并利用特定抽样条件下二元似然得分的渐近独立性简化区间计算。
材料陈述的贡献
摘要称,该方法在统计效率与计算效率之间提供权衡,并能降低置信区间的计算成本;以多元计数模型和转录组数据展示应用。
阅读关注点
应核对抽样参数条件、随机化如何改变估计量方差,以及得分渐近独立性的成立范围,并检查计算节省对应的统计效率损失。
阅读边界
仅据 OpenAlex 索引摘要,稿件版本未注明;抽样条件、置信区间公式和具体效率比较未提供,不能据此推断刊本变化或普遍优势。

原文摘要

Pairwise likelihood methods are commonly used for inference in parametric statistical models in cases where the full likelihood is too complex to be used, such as multivariate count data. Although pairwise likelihood methods represent a useful solution to perform inference for intractable likelihoods, several computational challenges remain. The pairwise likelihood function still requires the computation of a sum over all pairs of variables and all observations, which may be prohibitive in high dimensions. Moreover, it may be difficult to calculate confidence intervals of the resulting estimators, as they involve summing all pairs of pairs and all of the four-dimensional marginals. To alleviate these issues, we consider a randomized pairwise likelihood approach, where only summands randomly sampled across observations and pairs are used for the estimation. In addition to the usual tradeoff between statistical and computational efficiency, it is shown that, under a condition on the sampling parameter, this two-way random sampling mechanism makes the individual bivariate likelihood scores become asymptotically independent, allowing more computationally efficient confidence intervals to be constructed. The proposed approach is illustrated in tandem with copula-based models for multivariate count data in simulations, and in real data from a transcriptome study. Supplementary materials for this article are available online.

笔记与分组
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