An Elementary Approach to Weak Convergence for Quantile Processes, with Applications to Censored Survival Data
分位数过程弱收敛的初等方法及其在删失生存数据中的应用AI 解读 ↓
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分位数过程弱收敛的初等方法及其在删失生存数据中的应用AI 解读 ↓
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Let ξ be a continuously differentiable function with positive derivative, and let ξ n be a sequence of right-continuous increasing processes. We show that if n 1/2(ξ n − ξ) W, where W is continuous, then n 1/2(ξ−1 n − ξ−1) − W(ξ−1)/ξ′(ξ−1). This result is applied to classical processes such as the empirical distribution function, the Kaplan-Meier estimator, and some other situations. We also prove an analogous result for the bootstrapped version of n 1/2(ξ n − ξ) and show how this allows one to obtain confidence bands for the quantile function ξ−1, based on the bootstrap. Several examples are given.
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With the evolution of single-cell RNA sequencing techniques into a standard approach in genomics, it has become possible to conduct cohort-level causal inferences based on single-cell-level measurements. However, the individual gene expression levels of interest are not directly observable; instead, only repeated proxy measurements from each individual's cells are available, providing a derived outcome to estimate the underlying outcome for each of many genes. In this paper,…