A Fast Non-parametric Approach for Local Causal Structure Learning
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We study the problem of causal structure learning with essentially no assumptions on the functional relationships and noise. We develop DAG-FOCI, a computationally fast algorithm for this setting that is based on the FOCI variable selection algorithm in~\cite{azadkia2021simple}. DAG-FOCI outputs the set of parents of a response variable of interest. We provide theoretical guarantees of our procedure when the underlying graph does not contain any (undirected) cycle containing the response variable of interest. Furthermore, in the absence of this assumption, we give a conservative guarantee against false positive causal claims when the set of parents is identifiable. We demonstrate the applicability of DAG-FOCI on simulated as well as a real dataset from computational biology~\cite{sachs2005causal}.
超越固定截断时点:临床试验中的自适应限制平均生存时间方法
Summary Restricted mean survival time offers a compelling nonparametric alternative to hazard ratios for right-censored time-to-event data, particularly when the proportional hazards assumption is violated. By capturing the total event-free time over a specified horizon, it provides an intuitive and clinically meaningful measure of absolute treatment benefit. Nonetheless, selecting the restriction time poses challenges: choosing a small restriction time may overlook…
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Instrumental variable (IV) methods address treatment endogeneity, but with non-compliance and heterogeneous treatment effects a binary instrument generally identifies the local average treatment effect (LATE) among compliers rather than the population average treatment effect (ATE). When treatment effects and compliance probabilities are heterogeneous and dependent through latent factors, the ATE need not be identified by IV variation alone. We develop a proximal…
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I propose a locally robust semiparametric framework for estimating causal effects using examiner IV designs when adjustment for many or continuous covariates makes saturation infeasible or produces sparse cells. The key ingredient of this approach is an orthogonal moment function that removes the first-order effect of estimation errors in the two treatment regressions defining the examiner IV. I derive the orthogonal moment function and show that it remains valid under…
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条件边际效应估计的实用指南:现代方法
This Element offers a practical guide to estimating conditional marginal effects-how treatment effects vary with a moderating variable-using modern statistical methods. Commonly used approaches, such as linear interaction models, often suffer from unclarified estimands, limited overlap, and restrictive functional forms. This guide begins by clearly defining the estimand and presenting the main identification results. It then reviews and improves upon existing solutions, such…