Relative efficiency of the log rank test within a multiplicative intensity model
乘法强度模型中对数秩检验的相对效率AI 解读 ↓
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乘法强度模型中对数秩检验的相对效率AI 解读 ↓
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SUMMARY For large-sample clinical trials with independent individuals randomly allocated to two treatment groups, in which survival times follow a log linear multiplicative intensity model with treatment group as one covariate, this paper calculates the asymptotic relative efficiency of the log rank test for treatment effect as compared with the optimal score test. The method is to exhibit the failure hazard intensity, not of proportional hazards form, obtained by ignoring all covariates other than treatment group. The efficiency formulae are illustrated in two examples, and estimation from data of the loss of efficiency is illustrated for two clinical trial datasets.