Minimax second- and third-order designs to estimate the slope of a response surface

Designs for estimating the slope of a response surface are considered. Minimization of the variance of the estimated slope maximized over all points in the factor space is taken as the optimality criterion. Optimal designs under the minimax criterion are derived for second- and third-order polynomial regression over spherical regions.

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Conditional distribution equality testing is a core problem with applications in causal inference, model diagnostics, and transfer learning. Existing methods often lose power when the conditioning variable is high-dimensional. We propose a new test that leverages generative models to compare conditional distributions using both observed data and synthetic samples. A sample-splitting and studentization scheme is introduced to control estimation error. Under the null, the test…

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