Semiparametric Growth-Curve Modeling in Hierarchical, Longitudinal Studies
层级纵向研究中的半参数生长曲线建模AI 解读 ↓
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层级纵向研究中的半参数生长曲线建模AI 解读 ↓
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Modeling of growth (or decay) curves arises in many fields such as microbiology, epidemiology, marketing, and econometrics. Parametric forms like Logistic and Gompertz are often used for modeling such monotonic patterns. While useful for compact description, the real-life growth curves rarely follow these parametric forms perfectly. Therefore, the curve estimation methods that strike a balance between prior information in the parametric form and fidelity with the observed data are preferred. In hierarchical, longitudinal studies the interest lies in comparing the growth curves of different groups while accounting for the differences between the within-group subjects. This article describes a flexible state space modeling framework that enables semiparametric growth curve modeling for the data generated from hierarchical, longitudinal studies. The methodology, a type of functional mixed effects modeling, is illustrated with a real-life example of bacterial growth in different settings.
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Instrumental variable models with repeated endogenous treatments are popular in empirical research using pooled cross-sectional or short panel datasets. This paper proposes a novel semi-parametric approach that explicitly considers 1) path dependency in the contemporaneous treatment effect and 2) a direct carryover effect from past treatments. We demonstrate that when either of these new features is present, the standard two-stage least squares estimator is generally…