Multi-stage optimal dynamic treatment regimes for survival outcomes with dependent censoring
依赖删失下生存结局的多阶段最优动态处理策略AI 解读 ↓
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AI 根据所提供的论文材料归类:摘要以多阶段动态处理策略及其生存结局优化为核心,直接对应因果推断中的序列决策问题。
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Summary We propose a reinforcement learning method for estimating an optimal dynamic treatment regime for survival outcomes with dependent censoring. The estimator allows the failure time to be conditionally independent of censoring and dependent on the treatment decision times, supports a flexible number of treatment arms and treatment stages, and can maximize either the mean survival time or the survival probability at a certain time-point. The estimator is constructed using generalized random survival forests and can have polynomial rates of convergence. Simulations and analysis of the Atherosclerosis Risk in Communities study data suggest that the new estimator brings higher expected outcomes than existing methods in various settings.