Randomization Inference with Concentration Inequalities
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Randomization or design-based inference is becoming an increasingly popular tool for analysing data from randomized experiments: It does not require modelling assumptions on the distribution of outcomes or covariates, and hypothesis testing and estimation are respectively valid and unbiased in finite samples. Yet, confidence intervals for the sample average treatment effect (SATE) are still constructed via finite-population central limit theorems and their coverage is only asymptotic. In this work, we explore an alternative approach: We use concentration inequalities to construct confidence intervals for the SATE with non-asymptotic guarantees. We develop this approach for the most common experimental designs (Bernoulli trials and completely randomized experiments) and provide Hoeffding and Bernstein-type confidence intervals. Moreover, we extend these results to matched-pair, cluster and stratified randomized experiments. Our key technical contributions are a novel Bernstein-type concentration inequality for i.i.d. data points as well as a concentration result for Neyman's variance estimator.
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克隆—删失—加权方法的形式化与一致性
Target trial emulation has become a standard framework for causal inference from observational data. Within this paradigm, the clone-censor-weight (CCW) methodology provides a practical way to deal with complex treatment and adherence definitions when treatment regimes are not distinguishable at baseline. Despite its increasing use, the statistical interpretation of CCW remains limited. In this work, we formalize the CCW methodology from a statistical viewpoint based on…
非精确匹配何时能在无需调整的情况下保证平衡与有效推断?
One-to-one matching without replacement is a classical approach to constructing comparable treated and control samples in the design of observational studies. It pairs each treated unit with a distinct control while minimizing a covariate distance objective. With continuous covariates, the matched pairs generally remain inexact, which contributes to bias in downstream analysis. Its key theoretical properties, such as the resulting imbalance between matched pairs and when it…
We study nonparametric inference for a continuous-treatment causal dose-response curve and its first derivative under unmeasured confounding, using treatment- and outcome-inducing proxies. We establish a proximal doubly robust pseudo-outcome whose conditional mean given treatment equals the dose-response curve whenever either bridge function is correctly specified. Their (smoothed) efficient influence function representations lead to cross-fitted local-polynomial estimators…
以模型平均替代处理前趋势检验
We study difference-in-differences (DID) estimation of average treatment effects on the treated when the researcher is uncertain about which pre-treatment periods satisfy the parallel trends assumption. Roth (2022) shows that pre-trend testing can induce bias, complementing the statistical literature on post-selection inference. We propose the model averaged difference-in-differences (MADID) estimator, a weighted average of the candidate $2\times2$ DID estimators. The…
二元结果混合对照试验的稳健估计与推断:非小细胞肺癌案例
Hybrid controlled trials (HCTs), which augment randomized controlled trials (RCTs) with external controls (ECs), are increasingly receiving attention as a way to address limited power, slow accrual, and ethical concerns in clinical research. However, borrowing from ECs raises critical statistical challenges in estimation and inference, especially for binary outcomes where hidden bias is harder to detect and estimands such as risk difference, risk ratio, and odds ratio are of…