Dimension Reduction and Alleviation of Confounding for Spatial Generalized Linear Mixed Models
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Summary Non-Gaussian spatial data are very common in many disciplines. For instance, count data are common in disease mapping, and binary data are common in ecology. When fitting spatial regressions for such data, one needs to account for dependence to ensure reliable inference for the regression coefficients. The spatial generalized linear mixed model offers a very popular and flexible approach to modelling such data, but this model suffers from two major shortcomings: variance inflation due to spatial confounding and high dimensional spatial random effects that make fully Bayesian inference for such models computationally challenging. We propose a new parameterization of the spatial generalized linear mixed model that alleviates spatial confounding and speeds computation by greatly reducing the dimension of the spatial random effects. We illustrate the application of our approach to simulated binary, count and Gaussian spatial data sets, and to a large infant mortality data set.
RBF 核高斯过程最大似然估计的精确渐近理论
Gaussian processes (GPs) are widely used across machine learning, spatial statistics, time-series analysis, optimization, Bayesian statistics, and scientific applications. A central component of a GP model is its kernel, which is typically specified through a parametric family. Among the most widely used choices is the radial basis function (RBF), also known as the squared exponential or Gaussian kernel, owing to its simple form, smoothness, and flexibility. In practice, the…
离散空间随机场的有向图模型混合
Current approaches for modeling discrete-valued outcomes associated with spatially-dependent areal units incur computational and theoretical challenges, especially in the Bayesian setting when full posterior inference is desired. As an alternative, we propose a novel statistical modeling framework for this data setting, namely a mixture of directed graphical models (MDGMs). The components of the mixture, directed graphical models, can be represented by directed acyclic…
面向高维数据的残差树高斯过程建模框架
With the advance of measurement technologies and increasing computing power, large spatial data with heterogeneous structures are often collected over high-dimensional domains. Existing Gaussian process (GP) models and computational strategies are often inadequate for analyzing such datasets in multi-dimensional domains. To address these challenges, we develop a Bayesian residual tree GP methodology called ResTGP for large spatial data with potentially heterogeneous…
贝叶斯神经网络辅助多处理混合治愈生存模型:儿科肿瘤应用
Estimating covariate-conditional treatment effects in multi-arm oncology studies is complicated when treatment arms have common distributional features and a non-negligible fraction of patients achieve long-term remission. We propose a joint mixture cure model with covariate-dependent mixtures of log-normal kernels with treatment-specific inclusions. Both linear and neural-network-assisted non-linear covariate links are proposed. Specifically, the susceptible survival…
图分割贝叶斯因果森林:空间异质性处理效应估计
In spatial observational studies, treatment assignment and outcomes often exhibit spatial dependence patterns, and treatment effects may vary across space and subpopulations due to both measured and unmeasured spatially structured confounders. Accounting for spatial dependence while estimating heterogeneous treatment effects (HTEs) is a central task in spatial causal inference. Causal Bayesian additive regression tree methods are popular nonparametric methods for modeling…
具有结构化收缩与持续性先验的贝叶斯广义网络自回归模型
We propose a Bayesian generalized network autoregressive (BGNAR) model for multivariate time series whose component series are associated with the nodes of a known network. The proposed framework combines the parsimonious network structure of the generalized network autoregressive (GNAR) model with structured shrinkage and persistence priors adapted from Bayesian vector autoregressive (BVAR) modeling. We adapt Minnesota-type shrinkage to both own-lag and network-lag…