每日简报

存在干扰时的再随机化AI 解读

Covariates are widely used in randomized experiments to improve precision. However, in the presence of interference, where outcomes may depend on the treatment assignments of other units, standard covariate adjustment methods may fail to preserve desirable properties such as the no-harm property, meaning that incorporating covariates does not worsen estimator performance. Existing approaches that incorporate covariates under interference typically rely on specifying a…

非线性政治面板中的预测必要性与因果发现：民主化的反馈和动态AI 解读

A non-significant coefficient in a dynamic panel model need not imply the absence of a relationship. It may instead reflect heterogeneous effects averaged toward zero, reciprocal dynamics overlooked by a recursive specification, or relationships masked by the omission of correlated covariates. Standard linear estimators cannot distinguish among these possibilities. We develop an inferential workflow for political panel data that resolves this ambiguity by combining flexible…

通过最小二乘近似实现自适应 LASSO 惩罚的密度幂散度估计AI 解读

Linear mixed-effect panel data models are widely used in longitudinal biomedical, environmental, and social studies, but are often sensitive to data contamination and numerous covariates. To address these challenges, we propose a robust variable selection approach based on a least squares approximation (LSA) of the density power divergence (DPD) objective function combined with the Adaptive LASSO penalty. The LSA converts the nonlinear DPD objective into a computationally…

共同相关效应动态面板模型的自助法推断AI 解读

We study recursive-design wild bootstrap inference for dynamic panel data models with unobserved common factors estimated by Common Correlated Effects. In the large N,T setting, the bootstrap reproduces the biased limiting distribution in pure autoregressive models, but fails to capture all bias and factor-estimation variance components in models with additional regressors, particularly under weak exogeneity. We trace this failure to holding regressors fixed across bootstrap…

高维因果外推中的风险校准平衡AI 解读

In observational causal inference, covariate balancing is widely used to reduce source-target covariate shift, but under weak overlap in high dimensions, stronger balance can induce concentrated weights and increase variance. Balance measures how well the target covariate distribution is represented, but does not by itself determine how reliably the counterfactual mean can be estimated. We develop risk-calibrated balancing for the average treatment effect on the treated,…

目标试验模拟中的时间划分AI 解读

In target trial emulation, the treatment strategies that patients follow are inferred from the treatments they actually receive in routine care. However, in most settings, the outcome may preclude the observation of planned treatment, giving rise to immortal time bias through misclassification of treatment strategy, while markers of treatment response may influence subsequent treatment decisions, giving rise to time-varying confounding. A key step toward unbiased treatment…

数据驱动亚组发现后标准试验估计量的推断AI 解读

Data-driven subgroup identification is increasingly used in clinical trials, yet the effect reported for a discovered subgroup is typically the standard analysis: a Cox or generalized-linear-model treatment coefficient fitted within that subgroup. Selection by an effect-driven rule --- rewarding large estimated effects subject to screening and size criteria --- inflates the reported coefficient: a winner's curse invalidating naive intervals whether or not the identifier's…

插补就够了：平均处理效应估计的双稳健、半参数有效性与自动协变量平衡AI 解读

Imputation-based causal estimation is typically viewed as relying exclusively on an outcome model, in contrast to augmented inverse-probability weighting, whose consistency is protected by fitting two nuisance models. This paper argues that this view can be misleading by highlighting a hidden dual weighting structure in least-squares sieve regression imputation. Although only outcome regressions are explicitly fitted, the resulting imputation estimator admits an exact…

持续在线实验：动态处理下的序贯检验与错误发现率控制AI 解读

Generative AI has dramatically accelerated the rate at which new treatments---from novel pharmaceuticals to online marketing campaigns---can be conceived and deployed. As a result, modern experimentation platforms often run continuously, with treatments added as they are ready and removed when they underperform. We formalize this "Always-On" experimental setting, in which treatments can be dynamically generated, added to, and removed from a running experiment, and study the…

含时间趋势试验中的估计目标与估计方法AI 解读

In platform trials, model-based approaches typically estimate treatment effects conditional on calendar time. However, scientific and regulatory interest often lies in treatment effects defined for a target population spanning multiple enrollment periods, requiring explicit consideration of how effects should be averaged across time. This raises two fundamental challenges. The first is the definition of the appropriate target estimand when combining data across multiple…

不可测混杂下因果效应估计的近端平衡方法AI 解读

Estimating causal effects from observational data is central to science and policy, but the effects are not identified when confounders are unmeasured. Proximal causal inference addresses this problem with proxies of the unmeasured confounders. However, existing proxy-based approaches either designate proxy roles and solve an inverse problem, which is ill-posed and hard to estimate with high-dimensional proxies, or use a latent-variable model, which assumes that the learned…

熵正则化最优传输下的部分识别AI 解读

In many statistical settings, the available data and maintained assumptions do not suffice to uniquely identify the model parameters of interest. In such cases, one can only identify sets which are guaranteed to contain the true parameters. These are often characterized through linear programs that optimize over models compatible with the observed data. These programs can be infinite-dimensional in the optimizer and the number of constraints. We provide a unified way to…

二元结果配对研究的随机化推断AI 解读

We give an exact randomization-based confidence set for the average treatment effect (ATE) in matched-pair studies with a binary outcome, requiring neither monotonicity nor any distributional assumption beyond the within-pair coin flip. At its core is an analytic solution to the worst-case allocation of attributable effects: two binomial-symmetry lemmas identify the pattern hardest to reject as a single boundary corner, so testing null hypotheses needs no integer program and…

可变选择集下的需求估计：嵌套 Logit 的似然修正AI 解读

We derive the exact likelihood of the Berry (1994) share-form nested logit and show it contains a Jacobian term that depends on nest size and the nesting parameter. Omitting the term biases within-nest substitution estimates wherever choice sets vary across markets. Commonly-used count instruments for the within-nest share fail exclusion when product counts enter demand directly. The corrected likelihood identifies substitution without them, making crowding estimable. We…

动态网络形成中的同质性与传递性AI 解读

In social and economic networks linked agents often share connections in common. There are two competing explanations for this phenomenon. First, agents may have a structural taste for transitive links - the returns to linking may be higher if two agents share a common connection. Second, agents may assortatively match on unobserved attributes, a process called homophily. We study parameter identifiability in a simple model of dynamic network formation with both effects.…

Predict-then-optimize methods learn a mapping from features to unknown edge costs. They then solve the shortest-path problem on the predicted costs. We study a feature-free alternative for the case where the decision-maker observes many noisy cost vectors on a fixed network. The cost vectors are denoised by an eigenvalue decomposition (PCA) of their covariance matrix. Dijkstra's algorithm then runs on the result. We test this on the $5\times5$ grid of \citet{elmachtoub2022},…

多尺度混杂与测量误差下融合扰动实验和人群单细胞数据的因果路径分析AI 解读

Single-cell perturbation experiments provide causal information on gene regulation, whereas population-scale single-cell studies characterize gene expression and phenotypes in human populations. We develop a framework that integrates these complementary data sources for causal path analysis. Rather than assuming that a perturbational gene network transfers directly to the target population, we use externally learned ancestral relationships to constrain the network topology…

偏态结局纵向临床研究中的灵活治疗效应推断框架AI 解读

Longitudinal continuous outcomes in clinical trials are commonly analyzed using mixed models for repeated measures (MMRM) under normality assumptions. However, many clinical outcomes are skewed, making mean-based treatment effects difficult to interpret and potentially reducing statistical efficiency. The Box--Cox MMRM (BCMMRM) approach accommodates skewness by enabling inference on model-based median differences via inverse transformation. However, BCMMRM typically assumes…

有限状态嵌套 Markov 模型的递归头几何与无序有效推断AI 解读

Exploiting the equality restrictions that nested Markov models encode requires their tangent-space geometry. For strictly positive finite-state models on arbitrary acyclic directed mixed graphs (ADMGs), we differentiate the recursive-head chart and prove that the range of its score map is the full tangent space. Intrinsic-set coordinate blocks form an algebraic direct sum, blocks of distinct districts are orthogonal, and the resulting Gram projection needs neither…

第一阶段无法检测什么：线性工具变量中的函数形式污染AI 解读

Applied instrumental variables (IV) practice reports a first-stage F, now often the conditional F of Sanderson and Windmeijer (2016), and reads a large value as license to interpret the second stage. We show that no first-stage diagnostic can provide it. With a scalar instrument, a scalar treatment, and covariates entered linearly, the 2SLS estimand splits into a signal that a saturated specification would target and a contamination, the covariance between curvature in the…

生存治疗效应的有效迁移与推广AI 解读

Randomized controlled trials provide internally valid estimates of treatment effects, but their results may not directly apply to broader target populations due to differences in baseline covariate distributions, adherence to treatment or variations in outcome mechanisms. Under standard transport and time-to-event identifiability assumptions, we develop nonparametric, debiased machine learning estimators for transporting and generalizing causal survival treatment effect…

有序结果下的正交政策学习AI 解读

Policy learning methods based on conditional average treatment effects can obscure subpopulation heterogeneity when applied to ordinal outcomes. We develop a policy learning framework for ordinal outcomes with heterogeneous utilities for individuals who strictly benefit from treatment and those who do not. Since the probability of strict benefit is only partially identified without further conditions, we adopt a minimax strategy which minimizes the worst-case regret over the…

受约束分类与政策学习AI 解读

Modern machine learning approaches to classification, including AdaBoost, support vector machines, and deep neural networks, utilize surrogate loss techniques to circumvent the computational complexity of minimizing empirical classification risk. These techniques are also useful for causal policy learning problems, since estimation of individualized treatment rules can be cast as a weighted (cost-sensitive) classification problem. Consistency of the surrogate loss approaches…

长话短说：因果机器学习中的遗漏变量偏误AI 解读

We develop a general theory of omitted variable bias for a wide range of common causal parameters, including (but not limited to) averages of potential outcomes, average treatment effects, average causal derivatives, and policy effects from covariate shifts. Our theory applies to nonparametric models, while naturally allowing for (semi-)parametric restrictions (such as partial linearity) when such assumptions are made. We show how simple plausibility judgments on the maximum…