每日简报

收入分布与COPD患病率的空间异质成分回归：地理加权惩罚方法AI 解读

Income inequality is a major contributor to health disparities, yet its effects often vary by geography and are commonly represented as compositional distributions (e.g., proportions of households across income brackets). Existing spatial regression methods struggle in this setting: they typically assume smooth spatial variation, cannot accommodate abrupt spatial heterogeneity, and lack principled treatment of compositional covariates. We propose a geographically weighted…

用再生核控制任意结构假设空间中的错误发现AI 解读

Large-scale hypothesis testing is central to modern science, where controlling the False Discovery Rate (FDR) has become the standard approach to managing false positives across many simultaneous tests. Hypotheses rarely exist in isolation; they often exhibit structure through proximity, connectivity, or hierarchy. This structure represents both a challenge and an opportunity: while classical methods treat these dependencies as obstacles requiring conservative correction,…

尖峰协方差模型中自蒸馏在谱收缩估计量中的最优性AI 解读

Self-distillation has emerged as a promising technique for improving model performance in modern machine learning systems. We develop the statistical foundations of self-distillation in spiked covariance models, by introducing and analyzing a broad class of estimators, namely spectral shrinkage estimators. We establish that for spiked covariance matrices with $s$ spikes, $s$-step self-distillation achieves optimal performance among spectral shrinkage estimators,…

Fast Spawn&Prune：随机锥粒子梯度下降的全局收敛AI 解读

We investigate the global optimization of the objective function arising in continuous sparse regression, specifically the Beurling LASSO (BLASSO), over the space of measures. While Conic Particle Gradient Descent (CPGD) methods are computationally efficient, they may become trapped in local minima due to the non-convexity of the parameterization. To overcome this limitation, we introduce Fast Spawn\&Prune (FS\&P), a stochastic algorithm that extends FastPart introduced in…

群体感知矩阵估计与潜在子空间恢复AI 解读

Modern matrix completion problems often involve heterogeneous data whose rows simultaneously belong to many meta-categories, such as demographic and age groups in recommendation systems, or region and recording session labels in neural electrophysiological experiments. Standard low-rank estimators impose a single global latent geometry, which can recover average structure but may smooth away subgroup-specific variation, especially when observations are unevenly distributed…

稀疏回归中一般载荷的线性泛函检验：分离率与计算障碍AI 解读

We study the problem of testing $H_0: ξ^\topβ=t_0$ in high-dimensional sparse linear regression with Gaussian random design and unknown design covariance. The loading vector $ξ$ is arbitrary, and the exact sparsity level $k$ is unknown but bounded by a known value $k_u$. Tests are required to control Type I error uniformly over the $k_u$-sparse null, while power is evaluated against $k$-sparse alternatives. We construct a computationally efficient mixed test that gives an…

发散维协变量下Cox回归的实质模型相容多重插补AI 解读

Modern biomedical survival studies with high-dimensional genomic and clinical predictors are challenged by missing covariates. Existing methods conduct inference through penalization and debiasing when the number of covariates diverges with sample size, but they are typically developed with fully observed covariates. Conversely, substantive-model-compatible multiple imputation methods, particularly substantive-model-compatible fully conditional specification (SMC-FCS),…

面向稳健特征选择的大语言模型稀疏先验AI 解读

Large language models (LLMs) offer a scalable mechanism to elicit domain-informed prior information for high-dimensional variable selection. However, existing methods such as LLM-Lasso are sensitive to weight quality, with performance degrading substantially when LLM-generated weights are inaccurate. To address this challenge, we first introduce a framework for quantifying the quality of LLM-generated weights, enabling rigorous evaluation of LLM-informed methods across…

基于谱梯度重加权的稳健矩估计AI 解读

Moment-based estimation is a theoretically attractive approach to parametric inference, especially when likelihood-based estimation is unavailable, misspecified, or computationally inconvenient. However, the moment equations involve sample averages, which makes moment-based estimation sensitive to outliers. We propose the SGR-GMM algorithm, a robust generalized method of moments (GMM) procedure that uses a spectral gradient reweighting (SGR) primitive to soft-reweight the…

连接最大似然与最优传输：随机块模型的高效推断与模型选择AI 解读

We study inference in stochastic block models (SBMs) through the lens of optimal transport (OT). We first establish that maximum likelihood variational inference (MLVI) can be interpreted as a semi-relaxed Gromov-Wasserstein (srGW) projection with entropic regularization. While this formulation yields accurate clustering, the entropic regularization prevents transport plans to be sparse, hindering intrinsic model selection. Consequently, we investigate unregularized srGW…

高维数据中的测量误差：惩罚回归方法综述与比较AI 解读

In many important statistical analyses, the number of covariates $p$ often exceeds the data size $n$, a regime commonly referred to as high-dimensional. While considerable progress has been made in high-dimensional regression under the assumption of error-free covariates, real-world data frequently involve noisy or corrupted measurements. When left unaddressed, measurement errors can silently distort the analysis and mislead the conclusions. This paper reviews and evaluates…

面向复杂计算机模型的收缩约束函数标定AI 解读

We propose a new Bayesian model calibration formalism as an alternative to the Kennedy O'Hagan (KOH) framework which we term integrated bias with full uncertainty (IBFU). In KOH, calibration parameters are modeled as fixed, but unknown distributions with relatively weak prior constraints, and their posteriors are inferred jointly with an additive discrepancy Gaussian Process (GP). This formulation often provides limited regularization and leads to confounding pathologies…

基于多元混合效应模型的动态共表达网络估计AI 解读

High-throughput sequencing technologies have enabled the collection of large-scale longitudinal -omics data, providing new opportunities for studying co-expression networks among molecular nodes such as genes and proteins. However, the high dimensionality and temporal dependence inherent in such data require specialized statistical methods. We propose a novel approach to infer dynamic co-expression networks among features over time (DCENt), where each node (feature) is…

一致的贝叶斯局部空间特征选择及其在空间多模态组学中的应用AI 解读

Motivated by a high-dimensional regression problem in spatial multimodal omics (SMO), we propose a Bayesian framework for local spatial feature selection, where a random domain partition prior is introduced to divide the spatial domain into several contiguous clusters with flexible shapes and an unknown number of clusters, conditional on which a local feature selection prior is imposed within each cluster. The notion of "feature" is general and may include both covariates…

无特征值下界约束的多任务线性回归：自适应性、稳健性与安全性AI 解读

We study the multi-task linear regression problem in the presence of contaminated tasks. We address the setting where the unknown parameters of a majority of tasks are close in the $\ell_2$-norm, while a fraction of tasks are arbitrary outliers. Existing theoretical frameworks for this problem rely heavily on the assumption that the empirical second moment of each task has a minimum eigenvalue bounded away from zero (order $Ω(1)$). Crucially, this assumption fails in many…

无穷维球面核岭回归AI 解读

We introduce a novel regression framework designed to model non-linear responses situated on a sphere $\mathbb{S}$ of finite or infinite dimension. Unlike traditional tangent-space regressions, which lift responses to a tangent space $T_o \mathbb{S}$ and thereby violate intrinsic spherical distances, our proposed method employs an intrinsic approach. We model the conditional mean through an intercept $o \in \mathbb{S}$ and a linear predictor function $f: \mathfrak{X} \to T_o \mathbb{S}$…

网络 knockoffs：在二元空间中控制错误发现AI 解读

Phenomena such as epidemiological processes, hydrologic systems, social platforms, utility services, and supply chains can be represented as topological networks. A central question about these networks concerns connectivity and the permeability of edges. Dyadic regression and related approaches have been proposed to identify network features associated with pairwise node-level differences. In high-dimensional settings, it is important to control the number of spuriously…

可观测变量扩展下的在线稀疏回归AI 解读

Online high-dimensional regression has gained increasing attention in recent years, yet existing methods typically assume that all candidate features, including important ones, are observed from the outset of data collection. This assumption is often violated in real-world scenarios, where new variables become available gradually as data accumulate. To address this gap, we introduce a novel framework, Recurrent Adaptive Variable Selection (RAVAS), for online regression with…

组间不平衡下的风险异质性稳健推断AI 解读

Population-level heterogeneity is ubiquitous in biomedical data, where differences across demographic or clinical subgroups can substantially alter risk patterns. For example, in intensive care unit (ICU) studies, the mortality risk associated with specific admission diagnoses can vary across ethnic groups. Existing approaches for detecting risk heterogeneity are often sensitive to baseline model misspecification and regularization bias, both of which commonly arise in…

基于振荡控制归一化流的传输MCMC非空验证AI 解读

Transport MCMC trains a normalizing flow to precondition Metropolis--Hastings proposals, achieving high empirical efficiency on challenging posteriors; yet no prior work produces a numerically non-vacuous, rigorous spectral-gap bound for such samplers. We establish the first such bounds. For independence MH on the banana family we certify (γ^\ast = 0.828) at (D = 2) (covering in the original space) and (γ^\ast \ge 7.6\times 10^{-4}) at (D = 5) (covering in an analytically…

高维参考调节多期均值-方差投资组合优化AI 解读

The multiperiod mean-variance (MV) portfolio optimization serves as a vital expansion of Markowitz's static MV portfolio selection framework. Just like its static counterpart, the multiperiod MV portfolio remains susceptible to estimation errors. We propose a reference-regulated multiperiod mean-variance (RRMV) framework that penalizes deviations from a reference policy. Therefore, this new optimization successfully combines the advantages of dynamic strategies and reference…

带噪声与不精确边信息的样本高效归纳矩阵补全AI 解读

Inductive matrix completion (IMC) is a variant of low-rank matrix completion that incorporates row and column side-information. In principle, it can reduce the effective dimension of the recovery problem from the ambient matrix size to the dimension of the side-information features. Existing theory, however, does not fully realize this advantage in the noisy setting: sample-efficient guarantees only apply to noiseless recovery, while noisy guarantees require sample sizes…

对称性感知的高维协方差凸收缩估计AI 解读

We develop a class of data-adaptive shrinkage estimators for high-dimensional covariance estimation in which the shrinkage target is a Reynolds projection of the sample covariance under a finite symmetry group selected from a candidate library by held-out predictive performance. The class generalizes the convex shrinkage estimator of Ledoit and Wolf by replacing the scalar-identity target with a structured target derived from a symmetry group when one is available, and…

Probit 回归中的强对数凹性AI 解读

We show that strong log-concavity emerges in probit regression likelihoods without ridge penalization (i.e. Gaussian priors), unlike for the logistic case. Specifically, we provide: (a) a non-asymptotic characterization of strong log-concavity for fixed designs, similar to that for the existence of the maximum likelihood estimator (MLE) and (b) an asymptotic analysis for random designs, in the proportional regime when the sample size $n$ and the number of covariates $d$ grow…