每日简报

用于因果推断的可控生成式沙盒AI 解读

Method validation and study design in causal inference rely on synthetic data with known counterfactuals. Existing simulators trade off distributional realism, the ability to capture mixed-type and multimodal tabular data, against causal controllability, including explicit control over overlap, unmeasured confounding, and treatment effect heterogeneity. We introduce CausalMix, a variational generative framework that closes this gap by coupling a mixture of Gaussian latent…

缺失数据下纵向随机试验终点胜出概率的秩方法AI 解读

The primary analysis for longitudinal randomized controlled trials (RCTs) often compares treatment groups at the last timepoint, referred to as the landmark time. Assuming data are normally distributed and missing at random, the mixed model for repeated measures (MMRM) is widely used to conduct inference in terms of a mean difference. When outcomes violate normality assumption and/or the mean difference lacks a clear interpretation, we may quantify treatment effects using…

示证型实验AI 解读

Adaptive experiments are used extensively in online platforms, healthcare and biotechnology, and the social sciences. Often, the primary goal is not to precisely estimate a treatment effect but to demonstrate that at least one candidate intervention yields a positive effect, for some subpopulation and on some measured outcome. We formalize this objective as testing the global null in a threshold bandit framework, and develop two inference procedures that are valid under…

自然感染人群中疫苗对感染后结局的因果效应AI 解读

Understanding vaccine effects on post-infection outcomes is critical for evaluating the full value proposition of a vaccine. However, defining appropriate causal effects on such outcomes is challenging because infection is affected by vaccination. Existing approaches focus on the Doomed stratum, individuals who would be infected regardless of vaccine receipt. For many relevant outcomes, however, this estimand understates vaccine benefit by excluding individuals whose adverse…

条件分布处理效应：双重稳健估计与检验AI 解读

Beyond conditional average treatment effects, treatments may impact the entire outcome distribution in covariate-dependent ways, for example, by altering the variance or tail risks for specific subpopulations. We propose a novel estimand to capture such conditional distributional treatment effects, and develop a doubly robust estimator that is minimax optimal in the local asymptotic sense. Using this, we develop a test for the global homogeneity of conditional potential…

函数型线性分位数回归的变量选择：识别日常体力活动模式与认知功能的关联AI 解读

Quantile regression is useful for characterizing the conditional distribution of a response variable and understanding heterogeneity in the covariate effects at different quantiles. The rise of high-dimensional physiological data in biomedical research through wearable and sensor devices underscores the need for effective variable selection methods for interpretable and accurate quantile regression, which can offer robust insights into heterogeneous and dynamic covariate…

利用最佳顺序得分搜索学习时间序列因果结构AI 解读

Causal structure learning from observational data is central to many scientific and policy domains, but the time series setting common to many disciplines poses several challenges due to temporal dependence. In this paper we focus on score-based causal discovery for multivariate time series and introduce TS-BOSS, a time series extension of the recently proposed Best Order Score Search (BOSS) (Andrews et al. 2023). TS-BOSS performs a permutation-based search over dynamic…

基于复合的正则化回归：多流分布模型的可识别性、结构化惩罚与统计保证AI 解读

Regression by composition provides a flexible framework for constructing conditional distributions through sequential group actions. However, when multiple flows act on the same distribution, the model becomes non-identifiable, leading to flat likelihood regions and unstable estimates. We introduce a structured regularization framework that resolves this issue by assigning flow-specific penalties. The resulting estimator is defined as a penalized maximum likelihood problem…

识别应得决策规则以评估与实现公平AI 解读

We study fairness in decision-making when the data may encode systematic bias. Existing approaches typically impose fairness constraints while predicting the observed decision, which may itself be unfair. We propose a novel framework for characterising and addressing fairness issues by introducing the notion of desert decision, a latent variable representing the decision an individual rightfully deserves based on their actions, efforts, or abilities. This formulation shifts…

参数与半参数方法下的变量选择与响应误分类AI 解读

While variable selection has received extensive attention in the literature, its exploration in the presence of response measurement error remains underexplored. In this paper, we investigate this important problem within the context of binary classification with error-prone responses. We present valid variable selection procedures to address the complexities of response errors. Leveraging validation data, we introduce both parametric and semiparametric methodologies to…

Wasserstein 分布稳健分位数回归AI 解读

We study distributionally robust quantile regression using type-$p$ Wasserstein ambiguity sets. We derive a closed-form expression for the worst-case quantile regression loss under general $p$-Wasserstein uncertainty. We further give a uniqueness result showing that for $p>1$, the check loss yields the only class of convex loss functions for which such an additive Wasserstein regularization holds. Our analysis also uncovers qualitative differences between the regimes $p=1$ an…

阿尔茨海默病纵向数据的贝叶斯张量分位数回归AI 解读

As a general and robust alternative to traditional mean regression models, quantile regression avoids the assumption of normally distributed errors, making it a versatile choice when modeling outcomes such as cognitive scores that typically have skewed distributions. Motivated by an application to Alzheimer's disease data where the aim is to explore how brain-behavior associations change over time, we propose a novel Bayesian tensor quantile regression for high-dimensional…

张量网络依赖下的高维逻辑回归推断AI 解读

We investigate the problem of statistical inference for logistic regression with high-dimensional covariates in settings where dependence among individuals is induced by an underlying Markov random field. Going beyond the pairwise interaction models such as the Ising model, we consider a framework to accommodate more general tensor structures that capture higher-order dependencies. We develop a two-step procedure for low-dimensional linear and quadratic functionals. The…

三次与线性平滑样条的分位数回归AI 解读

Spline quantile regression (SQR) is a method introduced recently by Li and Megiddo (2026) for linear quantile regression where the regression coefficients are treated as smooth functions of the quantile level. With the coefficients represented by cubic splines with fixed knots on a given set of quantiles, the SQR method produces an estimate for the functional coefficients by solving a penalized quantile regression problem. The $\ell_1$-norm of the second derivatives of the…

熵正则化向量分位数回归的Sinkhorn算法AI 解读

Vector quantile regression (VQR) is an optimal transport (OT)-based framework that extends linear quantile regression to vector-valued response variables and can be formulated as an OT problem with a mean-independence constraint. In this paper, we study Sinkhorn-type algorithms for VQR with entropic regularization, building on the authors' previous work on its duality theory. We first study a direct adaptation of the classical Sinkhorn iteration based on solving the full…

双边市场双重随机化实验的回归调整AI 解读

Multiple randomization designs (MRDs) are a class of experimental designs used to handle interference in two-sided marketplaces. We investigate regression adjustment strategies for estimating total, spillover, and direct effects in MRDs. We derive minimum asymptotic variance estimators among a broad class of linearly adjusted estimators, without assuming a linear model on the potential outcomes. Surprisingly, the optimal regression adjustments are estimable from data and are…

如何解释净生存率：实际估计目标与通常理解的差异AI 解读

Net survival is conventionally defined as ``survival if cancer were the only possible cause of death'', an estimand corresponding to cancer-specific mortality alone. The Pohar Perme estimator targets this by removing general population other-cause mortality from observed total mortality, but achieves it only when cancer patients experience the same other-cause mortality as the general population. However, cancer patients often experience elevated other-cause mortality due to…

垄断竞争下利用收入数据识别和估计生产函数与消费者需求AI 解读

We establish nonparametric identification of production functions, total factor productivity (TFP), price markups, and firms' output prices and quantities, as well as consumer demand, using firm-level revenue data, without observing output quantity, in a monopolistically competitive environment with a fully nonparametric demand system. This result overturns the widely held view -- formalized by Bond, Hashemi, Kaplan, and Zoch (2021) -- that output elasticities and markups…

拓扑因果效应AI 解读

Estimating causal effects is particularly challenging when outcomes arise in complex, non-Euclidean spaces, where conventional methods often fail to capture meaningful structural variation. We develop a framework for topological causal inference that defines treatment effects through differences in the topological structure of potential outcomes, summarized by power-weighted silhouette functions of persistence diagrams. We develop an efficient, doubly robust estimator in a…

从观察数据估计广告视觉属性效应：生成图像辅助的双重机器学习AI 解读

Digital advertising increasingly relies on visual content, yet marketers lack rigorous methods for understanding how specific visual attributes causally affect consumer engagement. This paper addresses a fundamental methodological challenge: estimating causal effects when the treatment, such as a model's skin tone, is an attribute embedded within the image itself. Standard approaches like Double Machine Learning (DML) fail in this setting because vision encoders entangle…

回归不连续设计中直接估计条件平均处理效应的贝叶斯加性回归树AI 解读

Regression discontinuity designs (RDD) are widely used for causal inference. In many empirical applications, treatment effects vary substantially with covariates, and ignoring such heterogeneity can lead to misleading conclusions, which motivates flexible modeling of heterogeneous treatment effects in RDD. To this end, we propose a Bayesian nonparametric approach to estimating heterogeneous treatment effects based on Bayesian Additive Regression Trees (BART). The key feature…

从大语言模型中提取因果关系假说AI 解读

Large language models (LLMs) are trained on enormous amounts of data and encode knowledge in their parameters. We propose a pipeline to elicit causal relationships from LLMs. Specifically, (i) we sample many documents from LLMs on a given topic, (ii) we extract an event list from from each document, (iii) we group events that appear across documents into canonical events, (iv) we construct a binary indicator vector for each document over canonical events, and (v) we estimate…

利用外部对照开展试验近端学习：HIV 预防案例AI 解读

With the advent of effective pre-exposure prophylaxis agents, active-controlled HIV prevention trials have become a common study design. Nevertheless, estimating absolute efficacy relative to a placebo remains important. In this paper, we introduce a novel application of proximal causal inference methods to estimate the counterfactual cumulative HIV incidence under placebo for participants in an active-controlled trial of cabotegravir, using external control data from a…

纵向队列完全依从性因果效应：逆概率治疗加权与 G 估计比较AI 解读

Medication adherence is essential to ensure treatment effectiveness, but too often in routine care non-adherence compromises the desired outcome. We explore longitudinal causal modelling using observational data to estimate the time-varying effects of continuous drug adherence measures on health outcomes over a sustained period. The goal of such analyses is to quantify the potential impact of interventions to improve adherence on long-term health. We consider two established…