每日简报

计数型中间变量的主分层与 BART：生育对女性就业的效应AI 解读

Estimating the causal effect of fertility on women's employment is challenging because fertility and labour-market decisions are jointly determined. Instrumental-variable strategies are widely used, but credible instruments are rare and their validity often depends on covariates. Two-stage least squares, the dominant implementation, does not flexibly accommodate covariate-dependent instrument validity and is poorly suited to count-valued treatment and effect heterogeneity…

高维矩阵值时间序列的时空自回归AI 解读

Motivated by predicting intraday trading volume curves, we consider two spatio-temporal autoregressive models for matrix time series, in which each column may represent daily trading volume curve of one asset, and each row captures synchronized 5-minute volume intervals across multiple assets. While traditional matrix time series focus mainly on temporal evolution, our approach incorporates both spatial and temporal dynamics, enabling simultaneous analysis of interactions…

加权最小二乘估计量对遗漏变量的敏感性AI 解读

We introduce tools for assessing the sensitivity, to unobserved confounding, of a common estimator of causal effects that employs weights: the weighted linear regression of the outcome on the treatment and observed covariates. This estimator's bias is a function of two intuitive weighted partial $R^2$ values: (i) the proportion of weighted variance in the treatment that unobserved confounding explains given the covariates and (ii) the proportion of weighted variance in the…

高维混杂下纵向数据的异质性分位数处理效应估计（第二版）AI 解读

Causal inference plays a fundamental role in various real-world applications. However, in the motivating non-small cell lung cancer (NSCLC) study, it is challenging to estimate the treatment effect of chemotherapy on circulating tumor DNA (ctDNA). First, the heterogeneous treatment effects vary across patient subgroups defined by baseline characteristics. Second, there exists a broad set of demographic, clinical and molecular variables act as potential confounders. Third,…

医学研究中的回归不连续设计AI 解读

This article provides an introduction to the Regression Discontinuity (RD) design, and its application to empirical research in the medical sciences. While the main focus of this article is on causal interpretation, key concepts of estimation and inference are also briefly mentioned. A running medical empirical example is provided.

固定时间维度下异质性面板模型的双向均值组估计AI 解读

We consider a correlated random coefficient panel data model with two-way fixed effects and interactive fixed effects in a fixed T framework. We propose a two-way mean group (TW-MG) estimator for the expected value of the slope coefficient and propose a leave-one-out jackknife method for valid inference. We also consider a pooled estimator and provide a Hausman-type test for poolability. Simulations demonstrate the excellent performance of our estimators and inference…

统计学的挑战：因果关系与因果推断的十二项挑战AI 解读

Causality and causal inference have emerged as core research areas at the interface of modern statistics and domains including biomedical sciences, social sciences, computer science, and beyond. The field's inherently interdisciplinary nature -- particularly the central role of incorporating domain knowledge -- creates a rich and varied set of statistical challenges. Much progress has been made, especially in the last three decades, but there remain many open questions. Our…

三重稳健面板估计量AI 解读

This paper studies estimation of causal effects in a panel data setting. We introduce a new estimator, the Triply RObust Panel (TROP) estimator, that combines (i) a flexible model for the potential outcomes based on a low-rank factor structure on top of a two-way-fixed effect specification, with (ii) unit weights intended to upweight units similar to the treated units and (iii) time weights intended to upweight time periods close to the treated time periods. We study the…

多变量孟德尔随机化的一种更稳健方法AI 解读

Multivariable Mendelian randomization (MVMR) uses genetic variants as instrumental variables to infer the direct effects of multiple exposures on an outcome. However, unlike univariable Mendelian randomization, MVMR often faces greater challenges with many weak instruments, which can lead to bias not necessarily toward zero and inflation of type I errors. In this work, we introduce a new asymptotic regime that allows exposures to have varying degrees of instrument strength,…

基于联合特征函数的多元时间序列非参数分段AI 解读

Modern time series data often exhibit complex dependence and structural changes which are not easily characterised by shifts in the mean or model parameters. We propose a nonparametric data segmentation methodology for multivariate time series termed NP-MOJO. By considering joint characteristic functions between the time series and its lagged values, NP-MOJO is able to detect change points in the marginal distribution, but also those in possibly non-linear serial dependence,…

鞅的Yurinskii耦合AI 解读

Yurinskii's coupling is a popular theoretical tool for non-asymptotic distributional analysis in mathematical statistics and applied probability, offering a Gaussian strong approximation with an explicit error bound under easily verifiable conditions. Originally stated in $\ell_2$-norm for sums of independent random vectors, it has recently been extended both to the $\ell_p$-norm, for $1 \leq p \leq \infty$, and to vector-valued martingales in $\ell_2$-norm, under some…

评估时变调节作用的因果偏离效应元学习方法AI 解读

Advances in wearable technologies and health interventions delivered by smartphones have greatly increased the accessibility of mobile health (mHealth) interventions. Micro-randomized trials (MRTs) are designed to assess the effectiveness of the mHealth intervention and introduce a novel class of causal estimands called "causal excursion effects." These estimands enable the evaluation of how intervention effects change over time and are influenced by individual…

近似贝叶斯计算的网络推断：随机多群体神经质量模型示例AI 解读

In this article, we propose an adapted sequential Monte Carlo approximate Bayesian computation (SMC-ABC) algorithm for network inference in coupled stochastic differential equations (SDEs) used for multivariate time series modeling. Our approach is motivated by neuroscience, specifically the challenge of estimating brain connectivity before and during epileptic seizures. To this end, we make four key contributions. First, we introduce a 6N-dimensional SDE to model the…

高维混杂下的因果机器学习方法与交叉拟合AI 解读

Observational epidemiological studies commonly seek to estimate the causal effect of an exposure on an outcome. Adjustment for potential confounding bias in modern studies is challenging due to the presence of high-dimensional confounding, which occurs when there are many confounders relative to sample size or complex relationships between continuous confounders and exposure and outcome. Doubly robust methods such as Augmented Inverse Probability Weighting (AIPW) and…

回归不连续设计中的异质性处理效应发现AI 解读

The paper proposes a causal supervised machine learning algorithm to uncover treatment effect heterogeneity in sharp and fuzzy regression discontinuity (RD) designs. We develop a criterion for building an honest ``regression discontinuity tree'', where each leaf contains the RD estimate of a treatment conditional on the values of some pre-treatment covariates. It is a priori unknown which covariates are relevant for capturing treatment effect heterogeneity, and it is the…

树倒何处：依赖森林产业州的宏观经济预测AI 解读

Several key states in various regions of the U.S. have experienced recent sawtimber as well as pulp and paper mill closures, which raises an important policy question: how have and will key macroeconomic and industry specific indicators within the U.S. forest sector likely to change over time? This study provides empirical evidence to support forest-sector policy design by using a vector error correction (VEC) model to forecast economic trends in three major industries -…

带随机效应的生存时间与纵向结果因果联合模型：高维估计与变量选择AI 解读

We consider a joint survival and mixed-effects model to explain the survival time from longitudinal data and high-dimensional covariates in a population. The longitudinal data is modeled using a non linear mixed-effects model to account for the inter-individual variability in the population. The corresponding regression function serves as a link function incorporated into the survival model. In that way, the longitudinal data is related to the survival time. We consider a…

含噪声、非光滑与非凸矩条件模型的估计AI 解读

A practical challenge for structural estimation is the requirement to accurately minimize a sample objective function which is often non-smooth, non-convex, or both. This paper proposes a simple algorithm designed to find accurate solutions without performing an exhaustive search. It augments each iteration from a new Gauss-Newton algorithm with a grid search step. A finite sample analysis derives its optimization and statistical properties simultaneously using only…

治疗不依从下因果生存分析的多重稳健估计AI 解读

Comparative effectiveness research frequently addresses a time-to-event outcome and can require unique considerations in the presence of treatment noncompliance. Motivated by the challenges in addressing noncompliance in the ADAPTABLE pragmatic clinical trial, we develop a multiply robust estimator to estimate the principal survival causal effects under the principal ignorability and monotonicity. The multiply robust estimator is consistent even if one, and sometimes two, of…

PanelMatch：时间序列截面数据因果推断的匹配方法AI 解读

Analyzing time-series cross-sectional (also known as longitudinal or panel) data is an important process across a number of fields, including the social sciences, economics, finance, and medicine. PanelMatch is an R package that implements a set of tools enabling researchers to apply matching methods for causal inference with time-series cross-sectional data. Relative to other commonly used methods for longitudinal analyses, like regression with fixed effects, the…

用于代谢组缺失值插补的截断高斯无限因子模型AI 解读

Metabolomics is the study of small molecules in biological samples. Metabolomics data are typically high-dimensional and contain highly correlated variables and frequent missing values. Both missing at random (MAR) data, due to acquisition or processing errors, and missing not at random (MNAR) data, caused by values falling below detection thresholds, are common. Thus, imputation is a critical component of downstream analysis. Existing imputation methods generally assume one…

用于时间序列建模与预测的贝叶斯上下文树状态空间模型AI 解读

A hierarchical Bayesian framework is introduced for developing tree-based mixture models for time series, partly motivated by applications in finance and forecasting. At the top level, meaningful discrete states are identified as appropriately quantised values of some of the most recent samples. At the bottom level, a different, arbitrary base model is associated with each state. This defines a very general framework that can be used in conjunction with any existing model…

结合统计识别与潜在内生代理变量估计财政乘数AI 解读

Different proxy variables used in fiscal policy SVARs lead to contradicting conclusions regarding the size of fiscal multipliers. Our analysis suggests that the conflicting results may stem from violations of the proxy exogeneity assumptions. We propose a novel approach to include proxy variables into a Bayesian non-Gaussian SVAR, tailored to accommodate potentially endogenous proxies. Using our model, we find that increasing government spending is more effective in…

单指标模型中最佳子集选择的一致且可扩展算法AI 解读

Analysis of high-dimensional data has led to increased interest in both single index models (SIMs) and the best-subset selection. SIMs provide an interpretable and flexible modeling framework for high-dimensional data, while the best-subset selection aims to find a sparse model from a large set of predictors. However, the best-subset selection in high-dimensional models is known to be computationally intractable. Existing proxy algorithms are appealing but do not yield the…