A structural nested rate model for estimating the effects of time-varying exposure on recurrent event outcomes in the presence of death
死亡存在时估计时变暴露对复发事件影响的结构嵌套率模型
Assessing the causal effect of time-varying exposures on recurrent event processes is challenging in the presence of a terminating event. Our objective is to estimate both the short-term and delayed marginal causal effects of exposures on recurrent events while addressing the bias of a potentially correlated terminal event. Existing estimators based on marginal structural models and proportional rate models are unsuitable for estimating delayed marginal causal effects for…