每日简报

用于因果效应估计的正交约束深度工具变量模型AI 解读

OC-DeepIV is a neural network model designed for estimating causal effects. It characterizes heterogeneity by adding interaction features and reduces redundancy through orthogonal constraints. The model includes two feature extractors, one for the instrumental variable Z and the other for the covariate X*. The training process is divided into two stages: the first stage uses the mean squared error (MSE) loss function, and the second stage incorporates orthogonal…

联合建模多个终点以提高随机试验处理效应估计效率AI 解读

Randomized controlled trials are the gold standard for evaluating the efficacy of an intervention. However, there is often a trade-off between selecting the most scientifically relevant primary endpoint versus a less relevant, but more powerful, endpoint. For example, in the context of tobacco regulatory science many trials evaluate cigarettes per day as the primary endpoint instead of abstinence from smoking due to limited power. Additionally, it is often of interest to…

处理效应何以可识别？超越无混杂性的刻画与估计AI 解读

Most of the widely used estimators of the average treatment effect (ATE) in causal inference rely on the assumptions of unconfoundedness and overlap. Unconfoundedness requires that the observed covariates account for all correlations between the outcome and treatment. Overlap requires the existence of randomness in treatment decisions for all individuals. Nevertheless, many types of studies frequently violate unconfoundedness or overlap, for instance, observational studies…

组合取胜：用于分布外预测的模型平均AI 解读

Travel behaviour modellers have an increasingly diverse set of models at their disposal, ranging from traditional econometric structures to models from mathematical psychology and data-driven approaches from machine learning. A key question arises as to how well these different models perform in forecasting, especially when considering trips of different characteristics from those used in estimation, i.e. out-of-distribution prediction, and whether better predictions can be…

稳健高效的多单位交替实验AI 解读

User-randomized A/B testing has emerged as the gold standard for online experimentation. However, when this kind of approach is not feasible due to legal, ethical or practical considerations, experimenters have to consider alternatives like item-randomization. Item-randomization is often met with skepticism due to its poor empirical performance. To fill this gap, in this paper we introduce a novel and rich class of experimental designs, "Regular Balanced Switchback Designs"…

未观测混杂下的分位数最优政策学习AI 解读

We study quantile-optimal policy learning where the goal is to find a policy whose reward distribution has the largest $α$-quantile for some $α\in (0, 1)$. We focus on the offline setting whose generating process involves unobserved confounders. Such a problem suffers from three main challenges: (i) nonlinearity of the quantile objective as a functional of the reward distribution, (ii) unobserved confounding issue, and (iii) insufficient coverage of the offline dataset. To…

有限流动下双向效应的最优估计AI 解读

We propose an empirical Bayes estimator for two-way effects in linked data sets based on a novel prior that leverages patterns of assortative matching observed in the data. To capture limited mobility we model the bipartite graph associated with the matched data in an asymptotic framework where its Laplacian matrix has small eigenvalues that converge to zero. The prior hyperparameters that control the shrinkage are determined by minimizing an unbiased risk estimate. We show…

动态系统中的最优处理定向AI 解读

Modern treatment targeting methods often rely on estimating a conditional average treatment effect (CATE) using machine learning tools. While effective in identifying who benefits from treatment on the individual level, these approaches typically overlook system-level dynamics that may arise when treatments induce strain on shared capacity. We study the problem of targeting in Markovian systems, where treatment decisions must be made one at a time as units arrive, and early…

揭示观测研究中的偏差机制AI 解读

Observational studies are a key resource for causal inference but are often affected by systematic biases. Prior work has focused mainly on detecting these biases, via sensitivity analyses and comparisons with randomized controlled trials, or mitigating them through debiasing techniques. However, there remains a lack of methodology for uncovering the underlying mechanisms driving these biases, e.g., whether due to hidden confounding or selection of participants. In this…

面板数据的马赛克推断AI 解读

Analysis of panel data via linear regression is widespread across disciplines. To perform statistical inference, such analyses typically assume that clusters of observations are jointly independent. For example, one might assume that observations in New York are independent of observations in New Jersey. Are such assumptions plausible? Might there be hidden dependencies between nearby clusters? This paper introduces a mosaic permutation test that can (i) test the…

利用外部数据检验随机临床试验中的生物标志物交互效应AI 解读

In oncology the efficacy of novel therapeutics often differs across patient subgroups, and these variations are difficult to predict during the initial phases of the drug development process. The relation between the power of randomized clinical trials and heterogeneous treatment effects has been discussed by several authors. In particular, false negative results are likely to occur when the treatment effects concentrate in a subpopulation but the study design did not…

分组数据的非线性因果发现AI 解读

Inferring cause-effect relationships from observational data has gained significant attention in recent years, but most methods are limited to scalar random variables. In many important domains, including neuroscience, psychology, social science, and industrial manufacturing, the causal units of interest are groups of variables rather than individual scalar measurements. Motivated by these applications, we extend nonlinear additive noise models to handle random vectors,…

用机器学习与人工智能扩展并购模拟工具AI 解读

This paper develops a flexible approach to predict the price effects of horizontal mergers using ML/AI methods. While standard merger simulation techniques rely on restrictive assumptions about firm conduct, we propose a data-driven framework that relaxes these constraints when rich market data are available. We develop and identify a flexible nonparametric model of supply that nests a broad range of conduct models and cost functions. To overcome the curse of dimensionality,…

利用高阶累积量识别 lvLiNGAM 中的因果效应AI 解读

This paper investigates causal effect identification in latent variable Linear Non-Gaussian Acyclic Models (lvLiNGAM) using higher-order cumulants, addressing two prominent setups that are challenging in the presence of latent confounding: (1) a single proxy variable that may causally influence the treatment and (2) underspecified instrumental variable cases where fewer instruments exist than treatments. We prove that causal effects are identifiable with a single proxy or…

协变量自适应随机化下分布治疗效应的有效估计AI 解读

This paper focuses on the estimation of distributional treatment effects in randomized experiments that use covariate-adaptive randomization (CAR). These include designs such as Efron's biased-coin design and stratified block randomization, where participants are first grouped into strata based on baseline covariates and assigned treatments within each stratum to ensure balance across groups. In practice, datasets often contain additional covariates beyond the strata…

条件分布函数之间具有实际意义的差异AI 解读

In the framework of semiparametric distribution regression, we consider the problem of comparing the conditional distribution functions corresponding to two samples. In contrast to testing for exact equality, we are interested in the (null) hypothesis that the $L^2$ distance between the conditional distribution functions does not exceed a certain threshold in absolute value. The consideration of these hypotheses is motivated by the observation that in applications, it is…

结合肿瘤负荷与生存结局评价肿瘤试验处理效应AI 解读

In early-phase cancer clinical trials, the limited availability of data presents significant challenges in developing a framework to efficiently quantify treatment effectiveness. To address this, we propose a novel utility-based Bayesian approach for assessing treatment effects in these trials, where data scarcity is a major concern. Our approach synthesizes tumor burden, a key biomarker for evaluating patient response to oncology treatments, and survival outcome, a widely…

个体处理效应的预测区间与锐界AI 解读

Individual treatment effect (ITE) is often regarded as the ideal target of inference in causal analyses and has been the focus of several recent studies. In this paper, we describe the intrinsic limits regarding what can be learned concerning ITEs given data from large randomized experiments. We consider when a valid prediction interval for the ITE is informative and when it can be bounded away from zero. The joint distribution over potential outcomes is only partially…

经济与政策不确定性和企业价值：美国耐用品生产商AI 解读

The objective of this study is to analyze the response of firm value, represented by the Tobin's Q (Q) for a group of twelve U.S. durable goods producers to uncertainties in the US Economy. The results, based on an estimated panel quantile regressions (PQR) and panel vector autoregressive MIDAS model (PVM), show that Q for these firms reacts negatively to the positive shocks to the current ratio, and debt-to-asset ratio and positively to operating income after depreciation…

死亡存在时估计时变暴露对复发事件影响的结构嵌套率模型AI 解读

Assessing the causal effect of time-varying exposures on recurrent event processes is challenging in the presence of a terminating event. Our objective is to estimate both the short-term and delayed marginal causal effects of exposures on recurrent events while addressing the bias of a potentially correlated terminal event. Existing estimators based on marginal structural models and proportional rate models are unsuitable for estimating delayed marginal causal effects for…

协变量支持有限时已处理者平均处理效应的脆弱性AI 解读

This paper studies the identification of the average treatment effect on the treated (ATT) under unconfoundedness when covariate overlap is partial. A formal diagnostic is proposed to characterize empirical support -- the subset of the covariate space where ATT is point-identified due to the presence of comparable untreated units. Where support is absent, standard estimators remain computable but cease to identify meaningful causal parameters. A general sensitivity framework…

面板有限混合回归的成分数估计及生产函数异质性应用AI 解读

This paper develops statistical methods for determining the number of components in panel data finite mixture regression models with regression errors independently distributed as normal or more flexible normal mixtures. We analyze the asymptotic properties of the likelihood ratio test (LRT) and information criteria (AIC and BIC) for model selection in both conditionally independent and dynamic panel settings. Unlike cross-sectional normal mixture models, we show that panel…

广义因子结构面板模型的统计推断AI 解读

We consider identification, inference and validation of linear panel data models when both factors and factor loadings are accounted for by a nonparametric function. This general specification encompasses rather popular models such as the two-way fixed effects and the interactive fixed effects ones. By applying a conditional mean independence assumption between unobserved heterogeneity and the covariates, we obtain consistent estimators of the parameters of interest at the…

融合随机试验且效应修饰变量缺失时最优治疗规则的非参数估计AI 解读

A fundamental principle of clinical medicine is that a treatment should only be administered to those patients who would benefit from it. Treatment strategies that assign treatment to patients as a function of their individual characteristics are known as dynamic treatment rules. The dynamic treatment rule that optimizes the outcome in the population is called the optimal dynamic treatment rule. Randomized clinical trials are considered the gold standard for estimating the…