每日简报

使用大量相关弱工具和无效工具的稳健有效孟德尔随机化：去偏估计方程法AI 解读

Mendelian randomization (MR) is a widely used tool for causal inference in the presence of unmeasured confounders, which uses single nucleotide polymorphisms (SNPs) as instrumental variables to estimate causal effects. However, SNPs often have weak effects on complex traits, leading to bias in existing MR analysis when weak instruments are included. In addition, existing MR methods often restrict analysis to independent SNPs via linkage disequilibrium clumping and result in…

资产定价中的半参数条件因子模型AI 解读

We introduce a simple and tractable methodology for estimating semiparametric conditional latent factor models. Our approach disentangles the roles of characteristics in capturing factor betas of asset returns from ``alpha.'' We construct factors by extracting principal components from Fama-MacBeth managed portfolios. Applying this methodology to the cross-section of U.S. individual stock returns, we find compelling evidence of substantial nonzero pricing errors, even though…

部分和过程的函数型筛自助法及其变化点检测应用AI 解读

This paper applies the functional sieve bootstrap (FSB) to estimate the distribution of the partial sum process for time series stemming from a weakly stationary functional process. Consistency of the FSB procedure under weak assumptions on the underlying functional process is established. This result allows for the application of the FSB procedure to testing for a change-point in the mean of a functional time series using the CUSUM-statistic. We show that the FSB…

死亡截断下利用纳入生存信息的分位数估计观测数据处理效应AI 解读

The issue of "truncation by death" commonly arises in clinical research: subjects may die before their follow-up assessment, resulting in undefined clinical outcomes. To address this issue, we focus on survival-incorporated quantiles -- quantiles of a composite outcome combining death and clinical outcomes -- to summarize the effect of treatment. Using inverse probability of treatment weighting (IPTW), we propose an estimator for survival-incorporated quantiles from…

评估真实世界证据模拟研究对随机试验的可重复性AI 解读

Background: The standard regulatory approach to assess replication success is the two-trials rule, requiring both the original and the replication study to be significant with effect estimates in the same direction. The sceptical p-value was recently presented as an alternative method for the statistical assessment of the replicability of study results. Methods: We review the statistical properties of the sceptical p-value and compare those to the two-trials rule. We extend…

正交因果校准AI 解读

Estimates of heterogeneous treatment effects such as conditional average treatment effects (CATEs) and conditional quantile treatment effects (CQTEs) play an important role in real-world decision making. Given this importance, one should ensure these estimates are calibrated. While there is a rich literature on calibrating estimators of non-causal parameters, very few methods have been derived for calibrating estimators of causal parameters, or more generally estimators of…

协变量自适应随机化与不完全依从下处理效应的识别和推断AI 解读

Randomized controlled trials (RCTs) frequently utilize covariate-adaptive randomization (CAR) (e.g., stratified block randomization) and commonly suffer from imperfect compliance. This paper studies the identification and inference for the average treatment effect (ATE) and the average treatment effect on the treated (ATT) in such RCTs with a binary treatment. We first develop characterizations of the identified sets for both estimands. Since data are generally not i.i.d.…

随机实验分析入门与若干近期进展综述AI 解读

The past two decades have witnessed a surge of new research in the analysis of randomized experiments. The emergence of this literature may seem surprising given the widespread use and long history of experiments as the "gold standard" in program evaluation, but this body of work has revealed many subtle aspects of randomized experiments that may have been previously unappreciated. This article provides an overview of some of these topics, primarily focused on…

逆概率加权：从调查抽样到贝叶斯证据估计AI 解读

We consider the class of inverse probability weight (IPW) estimators, including the popular Horvitz-Thompson and Hajek estimators used routinely in survey sampling, causal inference and evidence estimation for Bayesian computation. We focus on the 'weak paradoxes' for these estimators due to two counterexamples by Basu [1988] and Wasserman [2004] and investigate the two natural Bayesian answers to this problem: one based on binning and smoothing : a 'Bayesian sieve' and the…

利用边际分布建模消费者选择的非参数方法AI 解读

Given data on the choices made by consumers for different offer sets, a key challenge is to develop parsimonious models that describe and predict consumer choice behavior while being amenable to prescriptive tasks such as pricing and assortment optimization. The marginal distribution model (MDM) is one such model, which requires only the specification of marginal distributions of the random utilities. This paper aims to establish necessary and sufficient conditions for given…

连续处理因果导数效应的双重稳健推断AI 解读

Statistical methods for causal inference with continuous treatments mainly focus on estimating the mean potential outcome function, commonly known as the dose-response curve. However, it is often not the dose-response curve but its derivative function that signals the treatment effect. In this paper, we investigate nonparametric inference on the derivative of the dose-response curve with and without the positivity condition. Under the positivity and other regularity…

用于实验设计的合成控制AI 解读

This article studies experimental design in settings where the experimental units are large aggregate entities (e.g., markets), and only one or a small number of units can be exposed to the treatment. In such settings, randomization of the treatment may result in treated and control groups with very different characteristics at baseline, inducing biases. We propose a variety of experimental non-randomized synthetic control designs (Abadie, Diamond and Hainmueller, 2010,…