每日简报

存在受试者协变量时受控实验的协同设计AI 解读

We consider the optimal experimental design problem of allocating subjects to treatment or control when subjects participate in multiple, separate controlled experiments within a short time-frame and subject covariate information is available. Here, in addition to subject covariates, we consider the dependence among the responses coming from the subject's random effect across experiments. In this setting, the goal of the allocation is to provide precise estimates of…

匹配型平均处理效应估计量的高斯与 Bootstrap 近似AI 解读

We establish Gaussian approximation bounds for covariate and rank-matching-based Average Treatment Effect (ATE) estimators. By analyzing these estimators through the lens of stabilization theory, we employ the Malliavin-Stein method to derive our results. Our bounds precisely quantify the impact of key problem parameters, including the number of matches and treatment balance, on the accuracy of the Gaussian approximation. Additionally, we develop multiplier bootstrap…

网络干扰下兼顾估计精度与遗憾的在线实验设计AI 解读

Network interference has attracted significant attention in the field of causal inference, encapsulating various sociological behaviors where the treatment assigned to one individual within a network may affect the outcomes of others, such as their neighbors. A key challenge in this setting is that standard causal inference methods often assume independent treatment effects among individuals, which may not hold in networked environments. To estimate interference-aware causal…

连续纵向中间变量下主层分层的敏感性分析：队列阶梯楔形试验应用AI 解读

Causal inference in the presence of intermediate variables is a challenging problem in many applications. Principal stratification (PS) provides a framework to estimate principal causal effects (PCE) in such settings. However, existing PS methods primarily focus on settings with binary intermediate variables. We propose a novel approach to estimate PCE with continuous intermediate variables in the context of stepped wedge cluster randomized trials (SW-CRTs). Our method…

终末事件存在时多结局总处理效应的非参数估计AI 解读

As standards of care advance, patients are living longer and once-fatal diseases are becoming manageable. Clinical trials increasingly focus on reducing disease burden, which can be quantified by the timing and occurrence of multiple non-fatal clinical events. Most existing methods for the analysis of multiple event-time data require stringent modeling assumptions that can be difficult to verify empirically, leading to treatment efficacy estimates that forego…

具有潜在组结构的面板随机前沿模型AI 解读

Stochastic frontier models have attracted considerable attention due to the incorporation of an inefficiency term in addition to the conventional error term. In this paper, we propose a general estimation framework for panel stochastic frontier models that accommodates potential heterogeneity through latent group structures. The framework is tailored to the distinctive features of stochastic frontier models and is paired with a practical hybrid estimation procedure that…

迭代式分布计算多项逻辑回归AI 解读

This article introduces an iterative distributed computing estimator for the multinomial logistic regression model with large choice sets. Compared to the maximum likelihood estimator, the proposed iterative distributed estimator achieves significantly faster computation and, when initialized with a consistent estimator, attains asymptotic efficiency under a weak dominance condition. Additionally, we propose a parametric bootstrap inference procedure based on the iterative…

集约边际与广延边际上的处理效应评估AI 解读

This paper provides a solution to the evaluation of treatment effects in selective samples when neither instruments nor parametric assumptions are available. We provide sharp bounds for average treatment effects under a conditional monotonicity assumption for all principal strata, i.e. units characterizing the complete intensive and extensive margins. Most importantly, we allow for a large share of units whose selection is indifferent to treatment, e.g. due to…

重复事件与竞争事件下的因果推断AI 解读

Many research questions concern treatment effects on outcomes that can recur several times in the same individual. For example, medical researchers are interested in treatment effects on hospitalizations in heart failure patients and sports injuries in athletes. Competing events, such as death, complicate causal inference in studies of recurrent events because once a competing event occurs, an individual cannot have more recurrent events. Several statistical estimands have…

短面板固定效应 Logit 模型中平均因果效应的识别与估计AI 解读

This paper studies identification and estimation of average causal effects, such as average marginal or treatment effects, in fixed effects logit models with short panels. Relating the identified set of these effects to an extremal moment problem, we first show how to obtain sharp bounds on such effects simply, without any optimization. We also consider even simpler outer bounds, which, contrary to the sharp bounds, do not require any first-step nonparametric estimators. We…

含固定效应的静态面板模型中的双重机器学习AI 解读

Recent advances in causal inference have seen the development of methods which make use of the predictive power of machine learning algorithms. In this paper, we develop novel double machine learning (DML) procedures for panel data in which these algorithms are used to approximate high-dimensional and nonlinear nuisance functions of the covariates. Our new procedures are extensions of the well-known correlated random effects, within-group and first-difference estimators from…

结合模型平均与匹配估计异方差下的条件平均处理效应AI 解读

We propose a model averaging approach, combined with a partition and matching method to estimate the conditional average treatment effects under heteroskedastic error settings. The proposed approach has asymptotic optimality and consistency of weights and estimator. Numerical studies show that our method has good finite-sample performances.

群体差距的非参数因果分解AI 解读

We introduce a new nonparametric causal decomposition approach that identifies the mechanisms by which a treatment variable contributes to a group-based outcome disparity. Our approach distinguishes three mechanisms: group differences in 1) treatment prevalence, 2) average treatment effects, and 3) selection into treatment based on individual-level treatment effects. Our approach reformulates classic Kitagawa-Blinder-Oaxaca decompositions in causal and nonparametric terms,…

GLACIAL：面向纵向影像研究的格兰杰与学习式因果分析AI 解读

The Granger framework is useful for discovering causal relations in time-varying signals. However, most Granger causality (GC) methods are developed for densely sampled timeseries data. A substantially different setting, particularly common in medical imaging, is the longitudinal study design, where multiple subjects are followed and sparsely observed over time. Longitudinal studies commonly track several biomarkers, which are likely governed by nonlinear dynamics that might…

通过因果发现与领域知识整合提升神经网络预测表现AI 解读

In this paper, we develop a generic methodology to encode hierarchical causality structure among observed variables into a neural network in order to improve its predictive performance. The proposed methodology, called causality-informed neural network (CINN), leverages three coherent steps to systematically map the structural causal knowledge into the layer-to-layer design of neural network while strictly preserving the orientation of every causal relationship. In the first…

因果效应推广与迁移的高效方法AI 解读

When estimating causal effects, it is important to assess external validity, i.e., determine how useful a given study is to inform a practical question for a specific target population. One challenge is that the covariate distribution in the population underlying a study may be different from that in the target population. If some covariates are effect modifiers, the average treatment effect (ATE) may not generalize to the target population. To tackle this problem, we…

长期剂量反应曲线的核方法AI 解读

A core challenge in causal inference is how to extrapolate long term effects, of possibly continuous actions, from short term experimental data. It arises in artificial intelligence: the long term consequences of continuous actions may be of interest, yet only short term rewards may be collected in exploration. For this estimand, called the long term dose response curve, we propose a simple nonparametric estimator based on kernel ridge regression. By embedding the…

一步平滑样条工具变量回归AI 解读

We extend nonparametric regression smoothing splines to a context where there is endogeneity and instrumental variables are available. Unlike popular existing estimators, the resulting estimator is one-step and relies on a unique regularization parameter. We derive rates of the convergence for the estimator and its first derivative, which are uniform in the support of the endogenous variable. We also address the issue of imposing monotonicity in estimation and extend the…

检测阴性设计下评估新冠疫苗有效性的双重机器学习方法AI 解读

The test-negative design (TND), which is routinely used for monitoring seasonal flu vaccine effectiveness (VE), has recently become integral to COVID-19 vaccine surveillance, notably in Québec, Canada. Some studies have addressed the identifiability and estimation of causal parameters under the TND, but efficiency bounds for nonparametric estimators of the target parameter under the unconfoundedness assumption have not yet been investigated. Motivated by the goal of…

平台试验中利用非同期对照识别与估计因果效应AI 解读

Platform trials are multi-arm designs that simultaneously evaluate multiple treatments for a single disease within the same overall trial structure. Unlike traditional randomized controlled trials, they allow treatment arms to enter and exit the trial at distinct times while maintaining a control arm throughout. This control arm comprises both concurrent controls, where participants are randomized concurrently to either the treatment or control arm, and non-concurrent…

潜在结果与do干预之间关系的澄清AI 解读

Most of the scientific literature on causal modeling considers the structural framework of Pearl and the potential-outcome framework of Rubin to be formally equivalent, and therefore interchangeably uses do-interventions and the potential-outcome subscript notation to write counterfactual outcomes. In this paper, we agnostically superimpose the two causal models to specify under which mathematical conditions structural counterfactual outcomes and potential outcomes need to,…

通过协变量选择优化平衡的自适应随机化方法AI 解读

Balancing influential covariates is crucial for valid treatment comparisons in clinical studies. While covariate-adaptive randomization is commonly used to achieve balance, its performance can be inadequate when the number of baseline covariates is large. It is therefore essential to identify the influential factors associated with the outcome and ensure balance among these critical covariates. In this article, we propose a novel adaptive randomization approach that…

含协变量的局部平均处理效应推断AI 解读

In theory, two-stage least squares (TSLS) identifies a weighted average of covariate-specific local average treatment effects (LATEs) from a saturated specification, without making parametric assumptions on how available covariates enter the model. In practice, TSLS is severely biased as saturation leads to a large number of control dummies and an equally large number of, arguably weak, instruments. This paper derives asymptotically valid tests and confidence intervals for…

形状约束函数型时间序列的状态空间建模AI 解读

Functional time series data frequently appears in econometric analyses, where the functions of interest are subject to some shape constraints, including monotonicity and convexity, as typical of the estimation of the Lorenz curve. This paper proposes a state-space model for time-varying functions to extract trends and serial dependence from functional time series while imposing the shape constraints on the estimated functions. The function of interest is modeled by a convex…