每日简报

QWO：加速线性高斯无环模型中的排列式因果发现AI 解读

Causal discovery is essential for understanding relationships among variables of interest in many scientific domains. In this paper, we focus on permutation-based methods for learning causal graphs in Linear Gaussian Acyclic Models (LiGAMs), where the permutation encodes a causal ordering of the variables. Existing methods in this setting are not scalable due to their high computational complexity. These methods are comprised of two main components: (i) constructing a…

条件矩限制下的机器学习去偏：局部平均处理效应应用AI 解读

Models with Conditional Moment Restrictions (CMRs) are popular in economics. These models involve finite and infinite dimensional parameters. The infinite dimensional components include conditional expectations, conditional choice probabilities, or policy functions, which might be flexibly estimated using Machine Learning tools. This paper presents a characterization of locally debiased moments for regular models defined by general semiparametric CMRs with possibly different…

以校准的 g 先验混合层级模型估计荟萃分析中的处理效应调节AI 解读

Assessing treatment effect moderation is critical in biomedical research and many other fields, as it guides personalized intervention strategies to improve participant's outcomes. Individual participant-level data meta-analysis (IPD-MA) offers a robust framework for such assessments by leveraging data from multiple trials. However, its performance is often compromised by challenges such as high between-trial variability. Traditional Bayesian shrinkage methods have gained…

结局独立的非随机缺失混杂下：因果效应界限与敏感性分析AI 解读

We report assumption-free bounds for any contrast between the probabilities of the potential outcome under exposure and non-exposure when the confounders are missing not at random. We assume that the missingness mechanism is outcome-independent. We also report a sensitivity analysis method to complement our bounds.

多重纳什均衡下的稳健网络干预配置AI 解读

Many policy problems involve designing individualized treatment allocation rules to maximize the equilibrium social welfare of interacting agents. Focusing on large-scale simultaneous decision games with strategic complementarities, we develop a method to estimate an optimal treatment allocation rule that is robust to the presence of multiple equilibria. Our approach remains agnostic about changes in the equilibrium selection mechanism under counterfactual policies, and we…

匹配估计量的 Bootstrap 一致性AI 解读

In a landmark paper, Abadie and Imbens (2008) showed that the naive bootstrap is inconsistent when applied to nearest neighbor matching estimators of the average treatment effect with a fixed number of matches. Since then, this finding has inspired numerous efforts to address the inconsistency issue, typically by employing alternative bootstrap methods. In contrast, this paper shows that the naive bootstrap is provably consistent for the original matching estimator, provided…

分布鲁棒的工具变量估计AI 解读

Instrumental variables (IV) estimation is a fundamental method in econometrics and statistics for estimating causal effects in the presence of unobserved confounding. However, challenges such as untestable model assumptions and poor finite sample properties have undermined its reliability in practice. Viewing common issues in IV estimation as distributional uncertainties, we propose DRIVE, a distributionally robust IV estimation method. We show that DRIVE minimizes a square…

未观测混杂下事件时间数据的二元变换模型：重访伊利诺伊再就业奖励实验AI 解读

Motivated by empirical studies investigating treatment effects in survival analysis, we propose a bivariate transformation model to quantify the impact of a binary treatment on a time-to-event outcome. The model equations are connected through a bivariate Gaussian distribution, with the dependence parameter capturing unobserved confounding, and are specified as functions of additive predictors to flexibly account for the impacts of observed confounders. Moreover, the…

具有选择性资格的纵向因果推断AI 解读

Dropout poses a significant challenge to causal inference in longitudinal studies with time-varying treatments. However, existing research does not simultaneously address dropout and time-varying treatments. We examine selective eligibility, an important yet overlooked source of non-ignorable dropout in such settings. This problem arises when a unit's prior treatment history influences its eligibility for subsequent treatments, a common scenario in medical and other…

基于变分因果推断的反事实生成建模AI 解读

Estimating an individual's counterfactual outcomes under interventions is a challenging task for traditional causal inference and supervised learning approaches when the outcome is high-dimensional (e.g. gene expressions, facial images) and covariates are relatively limited. In this case, to predict one's outcomes under counterfactual treatments, it is crucial to leverage individual information contained in the observed outcome in addition to the covariates. Prior works…

因果目标量选择的统一框架AI 解读

Estimating the causal effect of a treatment or health policy with observational data can be challenging due to an imbalance of and a lack of overlap between treated and control covariate distributions. In the presence of limited overlap, researchers choose between 1) methods (e.g., inverse probability weighting) that imply traditional estimands but whose estimators are at risk of considerable bias and variance; and 2) methods (e.g., overlap weighting) which imply a different…

横截面阶梯楔形整群随机试验中的中介分析AI 解读

Mediation analysis has been comprehensively studied for independent data but relatively little work has been done for correlated data, especially for the increasingly adopted stepped wedge cluster randomized trials (SW-CRTs). Motivated by challenges in underlying the effect mechanisms in pragmatic and implementation science clinical trials, we develop new methods for mediation analysis in SW-CRTs. Specifically, based on a linear and generalized linear mixed models, we…

利用偏度准则处理因果发现中的异方差噪声AI 解读

Real-world data often violates the equal-variance assumption (homoscedasticity), making it essential to account for heteroscedastic noise in causal discovery. In this work, we explore heteroscedastic symmetric noise models (HSNMs), where the effect $Y$ is modeled as $Y = f(X) + σ(X)N$, with $X$ as the cause and $N$ as independent noise following a symmetric distribution. We introduce a novel criterion for identifying HSNMs based on the skewness of the score (i.e., the…

Transformer 在上下文线性回归中处理内生性AI 解读

We explore the capability of transformers to address endogeneity in in-context linear regression. Our main finding is that transformers inherently possess a mechanism to handle endogeneity effectively using instrumental variables (IV). First, we demonstrate that the transformer architecture can emulate a gradient-based bi-level optimization procedure that converges to the widely used two-stage least squares $(\textsf{2SLS})$ solution at an exponential rate. Next, we propose…

使用估计倾向得分进行逆处理概率加权的调整 Nelson–Aalen 估计AI 解读

Inverse probability of treatment weighting (IPW) has been well applied in causal inference to estimate population-level estimands from observational studies. For time-to-event outcomes, the failure time distribution can be estimated by estimating the cumulative hazard in the presence of random right censoring. IPW can be performed by weighting the event counting process and at-risk process by the inverse treatment probability, resulting in an adjusted Nelson--Aalen estimator…

通过协变量调整提高复发事件曲线下面积估计精度AI 解读

The area under the curve (AUC) of the mean cumulative function (MCF) has recently been introduced as a novel estimand for evaluating treatment effects in recurrent event settings, offering an alternative to the commonly used Lin-Wei-Yang-Ying (LWYY) model. The AUC of the MCF provides a clinically interpretable summary measure that captures the overall burden of disease progression, regardless of whether the proportionality assumption holds. To improve the precision of the…

自然语言的孤立因果效应AI 解读

As language technologies become widespread, it is important to understand how changes in language affect reader perceptions and behaviors. These relationships may be formalized as the isolated causal effect of some focal language-encoded intervention (e.g., factual inaccuracies) on an external outcome (e.g., readers' beliefs). In this paper, we introduce a formal estimation framework for isolated causal effects of language. We show that a core challenge of estimating…

含暴露测量误差的灵活高效因果效应估计：控制变量法AI 解读

Exposure measurement error is a ubiquitous but often overlooked challenge in causal inference with observational data. Existing methods accounting for exposure measurement error largely rely on restrictive parametric assumptions, while emerging data-adaptive estimation approaches allow for less restrictive assumptions but at the cost of flexibility, as they are typically tailored towards rigidly-defined statistical quantities. There remains a critical need for…

推动平均处理效应AI 解读

The instrumental variable method is a prominent approach to recover under certain conditions, valid inference about a treatment causal effect even when unmeasured confounding might be present. In a groundbreaking paper, Imbens and Angrist (1994) established that a valid instrument nonparametrically identifies the average causal effect among compliers, also known as the local average treatment effect under a certain monotonicity assumption which rules out the existence of…

纵向因果推断中治疗模型的自适应稀疏化与平滑AI 解读

Causal variable selection in time-varying treatment settings is challenging due to evolving confounding effects. Existing methods mainly focus on time-fixed exposures and are not directly applicable to time-varying scenarios. We propose a novel two-step procedure for variable selection when modeling the treatment probability at each time point. We first introduce a novel approach to longitudinal confounder selection using a Longitudinal Outcome Adaptive LASSO (LOAL) that…

差分隐私下的协变量平衡因果推断AI 解读

Differential privacy is the leading mathematical framework for privacy protection, providing a probabilistic guarantee that safeguards individuals' private information when publishing statistics from a dataset. This guarantee is achieved by applying a randomized algorithm to the original data, which introduces unique challenges in data analysis by distorting inherent patterns. In particular, causal inference using observational data in privacy-sensitive contexts is…

冠状动脉旁路移植术后再住院的性别差异：MIMIC-IV 数据的稀疏函数因果中介分析AI 解读

Hospital readmissions following coronary artery bypass grafting (CABG) not only impose a substantial cost burden on healthcare systems but also serve as a potential indicator of the quality of medical care. Previous studies of gender effects on complications after CABG surgery have consistently revealed that women tend to suffer worse outcomes. To better understand the causal pathway from gender to the number of rehospitalisations, we study the postoperative central venous…

多组临床试验中死亡截断结局的双重稳健估计与敏感性分析AI 解读

In clinical trials, the observation of participant outcomes may frequently be hindered by death, leading to ambiguity in defining a scientifically meaningful final outcome for those who die. Principal stratification methods are valuable tools for addressing the average causal effect among always-survivors, i.e., the average treatment effect among a subpopulation defined as those who would survive regardless of treatment assignment. Although robust methods for the…

政策学习中最优福利的置信下界AI 解读

We study inference on the optimal welfare in a policy learning problem and propose reporting a lower confidence band (LCB). A natural approach to constructing an LCB is to invert a one-sided t-test based on an efficient estimator for the optimal welfare. However, we show that for an empirically relevant class of DGPs, such an LCB can be first-order dominated by an LCB based on a welfare estimate for a suitable suboptimal treatment policy. We show that such first-order…