每日简报

利用双重机器学习估计因果效应：方法评估AI 解读

The estimation of causal effects with observational data continues to be a very active research area. In recent years, researchers have developed new frameworks which use machine learning to relax classical assumptions necessary for the estimation of causal effects. In this paper, we review one of the most prominent methods - "double/debiased machine learning" (DML) - and empirically evaluate it by comparing its performance on simulated data relative to more traditional…

簇规模不可忽略时簇随机实验的统计推断AI 解读

This paper considers the problem of inference in cluster randomized experiments when cluster sizes are non-ignorable. Here, by a cluster randomized experiment, we mean one in which treatment is assigned at the cluster level. By non-ignorable cluster sizes, we refer to the possibility that the treatment effects may depend non-trivially on the cluster sizes. We frame our analysis in a super-population framework in which cluster sizes are random. In this way, our analysis…

连续暴露因果效应曲线的多重稳健双重差分估计AI 解读

Researchers commonly use difference-in-differences (DiD) designs to evaluate public policy interventions. While methods exist for estimating effects in the context of binary interventions, policies often result in varied exposures across regions implementing the policy. Yet, existing approaches for incorporating continuous exposures face substantial limitations in addressing confounding variables associated with intervention status, exposure levels, and outcome trends. These…

用于估计因果效应的局部因果发现AI 解读

Even when the causal graph underlying our data is unknown, we can use observational data to narrow down the possible values that an average treatment effect (ATE) can take by (1) identifying the graph up to a Markov equivalence class; and (2) estimating that ATE for each graph in the class. While the PC algorithm can identify this class under strong faithfulness assumptions, it can be computationally prohibitive. Fortunately, only the local graph structure around the…

随机实验中通用机器学习发现的异质性处理效应：统计推断AI 解读

Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects under practical settings with many covariates and small sample size. In addition, the quantification of estimation uncertainty remains a challenge. We develop a general approach to statistical inference for heterogeneous treatment effects…

应对 A/B 测试中数据训练循环引发的干扰：加权训练方法AI 解读

In modern recommendation systems, the standard pipeline involves training machine learning models on historical data to predict user behaviors and improve recommendations continuously. However, these data training loops can introduce interference in A/B tests, where data generated by control and treatment algorithms, potentially with different distributions, are combined. To address these challenges, we introduce a novel approach called weighted training. This approach…

连续时间生存与事件史分析中边际因果效应识别的图准则AI 解读

We consider continuous-time survival or more general event-history settings, where the aim is to infer the causal effect of a time-dependent treatment process. This is formalised as the effect on the outcome event of a (possibly hypothetical) intervention on the intensity of the treatment process, i.e. a stochastic intervention. To establish whether valid inference about the interventional situation can be drawn from typical observational, i.e. non-experimental, data we…

跨研究异质性处理效应估计的多研究 R-learnerAI 解读

Estimating heterogeneous treatment effects (HTEs) is crucial for precision medicine. While multiple studies can improve the generalizability of results, leveraging them for estimation is statistically challenging. Existing approaches often assume identical HTEs across studies, but this may be violated due to various sources of between-study heterogeneity, including differences in study design, study populations, and data collection protocols, among others. To this end, we…

没有外生变异时反向因果关系的可检验性AI 解读

This paper shows that testability of reverse causality is possible even in the absence of exogenous variation, such as in the form of instrumental variables. Instead of relying on exogenous variation, we achieve testability by imposing relatively weak model restrictions and exploiting that a dependence of residual and purported cause is informative about the causal direction. Our main assumption is that the true functional relationship is nonlinear and that error terms are…

改进多地点试验中地点特定效应及其分布的估计AI 解读

In multisite trials, researchers are often interested in several inferential goals: estimating treatment effects for each site, ranking these effects, and studying their distribution. This study seeks to identify optimal methods for estimating these targets. Through a comprehensive simulation study, we assess two strategies and their combined effects: semiparametric modeling of the prior distribution, and alternative posterior summary methods tailored to minimize specific…

用于面板数据因果推断的预测算法AI 解读

Conducting causal inference with panel data is a core challenge in social science research. We adapt a deep neural architecture for time series forecasting (the N-BEATS algorithm) to more accurately impute the counterfactual evolution of a treated unit had treatment not occurred. Across a range of settings, the resulting estimator (``SyNBEATS'') significantly outperforms commonly employed methods (synthetic controls, two-way fixed effects), and attains comparable or more…

lmw：用于因果推断的线性模型权重AI 解读

The linear regression model is widely used in the biomedical and social sciences as well as in policy and business research to adjust for covariates and estimate the average effects of treatments. Behind every causal inference endeavor there is a hypothetical randomized experiment. However, in routine regression analyses in observational studies, it is unclear how well the adjustments made by regression approximate key features of randomized experiments, such as covariate…

通过幂似然结合实验与观察数据AI 解读

Randomized controlled trials are the gold standard for causal inference and play a pivotal role in modern evidence-based medicine. However, the sample sizes they use are often too limited to draw significant causal conclusions for subgroups that are less prevalent in the population. In contrast, observational data are becoming increasingly accessible in large volumes but can be subject to bias as a result of hidden confounding. Given these complementary features, we propose…

混杂下的悲观策略：部分可观测决策过程中的高效离线强化学习AI 解读

We study offline reinforcement learning (RL) in partially observable Markov decision processes. In particular, we aim to learn an optimal policy from a dataset collected by a behavior policy which possibly depends on the latent state. Such a dataset is confounded in the sense that the latent state simultaneously affects the action and the observation, which is prohibitive for existing offline RL algorithms. To this end, we propose the \underline{P}roxy variable…

已知倾向得分下个体治疗获益概率的高置信度推断AI 解读

We seek to understand the probability an individual benefits from treatment (PIBT), an inestimable quantity that must be bounded in practice. Given the innate uncertainty in the population-level bounds on PIBT, we seek to better understand the margin of error for their estimation in order to discern whether the estimated bounds on PIBT are tight or wide due to random chance or not. Toward this goal, we present guarantees to the estimation of bounds on marginal PIBT, with any…

连续处理后变量的主层分层：非参数识别与半参数估计AI 解读

Post-treatment variables often complicate causal inference. They appear in many scientific problems, including noncompliance, truncation by death, mediation, and surrogate endpoint evaluation. Principal stratification is a strategy to address these challenges by adjusting for the potential values of the post-treatment variables, defined as the principal strata. It allows for characterizing treatment effect heterogeneity across principal strata and unveiling the mechanism of…

相信你的梯度：面向因果发现的梯度式干预目标选择AI 解读

Inferring causal structure from data is a challenging task of fundamental importance in science. Observational data are often insufficient to identify a system's causal structure uniquely. While conducting interventions (i.e., experiments) can improve the identifiability, such samples are usually challenging and expensive to obtain. Hence, experimental design approaches for causal discovery aim to minimize the number of interventions by estimating the most informative…

基于双重机器学习的因果混合建模AI 解读

Hybrid modeling integrates machine learning with scientific knowledge to enhance interpretability, generalization, and adherence to natural laws. Nevertheless, equifinality and regularization biases pose challenges in hybrid modeling to achieve these purposes. This paper introduces a novel approach to estimating hybrid models via a causal inference framework, specifically employing Double Machine Learning (DML) to estimate causal effects. We showcase its use for the Earth…

最优加权平均导数效应AI 解读

Weighted average derivative effects (WADEs) are nonparametric estimands with uses in economics and causal inference. Debiased WADE estimators typically require learning the conditional mean outcome as well as a Riesz representer (RR) that characterises the requisite debiasing corrections. RR estimators for WADEs often rely on kernel estimators, introducing complicated bandwidth-dependant biases. In our work we propose a new class of RRs that are isomorphic to the class of…

可逆潜在因果模型中领域反事实的刻画AI 解读

Answering counterfactual queries has important applications such as explainability, robustness, and fairness but is challenging when the causal variables are unobserved and the observations are non-linear mixtures of these latent variables, such as pixels in images. One approach is to recover the latent Structural Causal Model (SCM), which may be infeasible in practice due to requiring strong assumptions, e.g., linearity of the causal mechanisms or perfect atomic…

分层随机化的组合中心极限定理AI 解读

This paper establishes a combinatorial central limit theorem for stratified randomization, which holds under a Lindeberg-type condition. The theorem allows for an arbitrary number or sizes of strata, with the sole requirement being that each stratum contains at least two units. This flexibility accommodates both a growing number of large and small strata simultaneously, while imposing minimal conditions. We then apply this result to derive the asymptotic distributions of two…

非负两部分结局的两步目标最小损失估计AI 解读

Non-negative two-part outcomes are defined as outcomes with a density function that have a zero point mass but are otherwise positive. Examples, such as healthcare expenditure and hospital length of stay, are common in healthcare utilization research. Despite the practical relevance of non-negative two-part outcomes, very few methods exist to leverage knowledge of their semicontinuity to achieve improved performance in estimating causal effects. In this paper, we develop a…

始终存活者及其他人群因果效应界限的统一框架AI 解读

We investigate the bounding problem of causal effects in experimental studies in which the outcome is truncated by death, meaning that the subject dies before the outcome can be measured. Causal effects cannot be point identified without instruments and/or tight parametric assumptions but can be bounded under mild restrictions. Previous work on partial identification under the principal stratification framework has primarily focused on the `always-survivor' subpopulation. In…

马氏平衡：近似协变量平衡的多变量视角AI 解读

In the past decade, various exact balancing-based weighting methods were introduced to the causal inference literature. Exact balancing alleviates the extreme weight and model misspecification issues that may incur when one implements inverse probability weighting. It eliminates covariate imbalance by imposing balancing constraints in an optimization problem. The optimization problem can nevertheless be infeasible when there is bad overlap between the covariate distributions…