每日简报

二元随机实验中符合因果结构的先验AI 解读

We introduce the BREASE framework for the Bayesian analysis of randomized controlled trials with a binary treatment and a binary outcome. Approaching the problem from a causal inference perspective, we propose parameterizing the likelihood in terms of the baselinerisk, efficacy, and adverse side effects of the treatment, along with a flexible, yet intuitive and tractable jointly independent beta prior distribution on these parameters, which we show to be a generalization of…

通过聚类改善差分隐私随机实验的方差AI 解读

Estimating causal effects from randomized experiments is only possible if participants are willing to disclose their potentially sensitive responses. Differential privacy, a widely used framework for ensuring an algorithms privacy guarantees, can encourage participants to share their responses without the risk of de-anonymization. However, many mechanisms achieve differential privacy by adding noise to the original dataset, which reduces the precision of causal effect…

非精确匹配观察研究中平均处理效应的随机化推断AI 解读

Matching is a widely used causal inference design that aims to approximate a randomized experiment using observational data by forming matched sets of treated and control units based on similarities in their covariates. Ideally, treated units are exactly matched with controls on these covariates, enabling randomization-based inference for treatment effects as in a randomized experiment, under the assumption of no unobserved covariates. However, inexact matching often occurs,…

随机效应的个体化收缩估计AI 解读

This paper develops an approach to random effects estimation and individual-level forecasting in micropanels that targets individual accuracy rather than aggregate performance. The conventional shrinkage methods used in the literature, such as the James-Stein estimator and Empirical Bayes, target aggregate performance and can lead to inaccurate decisions at the individual level. We propose a class of shrinkage estimators with individual weights (IW) that leverage an…

产品内生进入与退出下需求模型的识别和估计AI 解读

Firms introduce products in markets where they anticipate stronger demand, using information unobserved by researchers. This creates endogenous selection in demand estimation. In differentiated-product oligopolies, multidimensional demand unobservables and strategic entry can render the ordinary propensity score insufficient for selection correction. Existing approaches either restrict firms' information at entry or jointly estimate demand, pricing, and entry under strong…

混合成员模型中混合概率与排序的推断AI 解读

Network data is prevalent in numerous big data applications including economics and health networks where it is of prime importance to understand the latent structure of network. In this paper, we model the network using the Degree-Corrected Mixed Membership (DCMM) model. In DCMM model, for each node $i$, there exists a membership vector $\boldsymbolπ_ i = (\boldsymbolπ_i(1), \boldsymbolπ_i(2),\ldots, \boldsymbolπ_i(K))$, where $\boldsymbolπ_i(k)$ denotes the weight that…

通过分位数平衡开展逆倾向加权的锐敏感性分析AI 解读

Inverse propensity weighting (IPW) is a popular method for estimating treatment effects from observational data. However, its correctness relies on the untestable (and frequently implausible) assumption that all confounders have been measured. This paper introduces a robust sensitivity analysis for IPW that estimates the range of treatment effects compatible with a given amount of unobserved confounding. The estimated range converges to the narrowest possible interval (under…

平衡权重估计的可解释敏感性分析AI 解读

Assessing sensitivity to unmeasured confounding is an important step in observational studies, which typically estimate effects under the assumption that all confounders are measured. In this paper, we develop a sensitivity analysis framework for balancing weights estimators, an increasingly popular approach that solves an optimization problem to obtain weights that directly minimizes covariate imbalance. In particular, we adapt a sensitivity analysis framework using the…

跨多产品类别消费者选择的反事实推断AI 解读

This paper proposes a method for estimating consumer preferences among discrete choices, where the consumer chooses at most one product in a category, but selects from multiple categories in parallel. The consumer's utility is additive in the different categories. Her preferences about product attributes as well as her price sensitivity vary across products and are in general correlated across products. We build on techniques from the machine learning literature on…

对数因变量与双重差分：变换的风险AI 解读

The log transformation of the dependent variable is not innocuous when using a difference-in-differences (DD) model. With a dependent variable in logs, the DD term captures an approximation of the proportional difference in growth rates across groups. As I show with both simulations and two empirical examples, if the baseline outcome distributions are sufficiently different across groups, the DD parameter for a log-specification can be different in sign to that of a…

随机缺失协变量下倾向得分分析的多重插补：插补内与跨插补方法AI 解读

In epidemiology and social sciences, propensity score methods are popular for estimating treatment effects using observational data, and multiple imputation is popular for handling covariate missingness. However, how to appropriately use multiple imputation for propensity score analysis is not completely clear. This paper aims to bring clarity on the consistency (or lack thereof) of methods that have been proposed, focusing on the within approach (where the effect is…

时间序列极端事件中的因果关系AI 解读

Consider two stationary time series with heavy-tailed marginal distributions. We aim to detect whether they have a causal relation, that is, if a change in one causes a change in the other. Usual methods for causal discovery are not well suited if the causal mechanisms only appear during extreme events. We propose a framework to detect a causal structure from the extremes of time series, providing a new tool to extract causal information from extreme events. We introduce the…

早期肿瘤试验混合对照方法评估：基于MORPHEUS-UC的模拟研究AI 解读

Phase Ib/II oncology trials, despite their small sample sizes, aim to provide information for optimal internal company decision-making concerning novel drug development. Hybrid controls (a combination of the current control arm and controls from one or more sources of historical trial data [HTD]) can be used to increase the statistical precision. Here we assess combining two sources of Roche HTD to construct a hybrid control in targeted therapy for decision-making via an…

CUTS+：不规则时间序列中的高维因果发现AI 解读

Causal discovery in time-series is a fundamental problem in the machine learning community, enabling causal reasoning and decision-making in complex scenarios. Recently, researchers successfully discover causality by combining neural networks with Granger causality, but their performances degrade largely when encountering high-dimensional data because of the highly redundant network design and huge causal graphs. Moreover, the missing entries in the observations further…

超越尖锐零假设的随机化推断：有界零假设与个体处理效应分位数AI 解读

Randomization inference (RI) is typically interpreted as testing Fisher's "sharp" null hypothesis that all unit-level effects are exactly zero. This hypothesis is often criticized as restrictive and implausible, making its rejection scientifically uninteresting. We show, however, that many randomization tests are also valid for a "bounded" null hypothesis under which the unit-level effects are all non-positive (or all non-negative) but are otherwise heterogeneous. In…

近端中介分析AI 解读

A common concern when trying to draw causal inferences from observational data is that the measured covariates are insufficiently rich to account for all sources of confounding. In practice, many of the covariates may only be proxies of the latent confounding mechanism. Recent work has shown that in certain settings where the standard 'no unmeasured confounding' assumption fails, proxy variables can be leveraged to identify causal effects. Results currently exist for the…

固定效应与广义 Mundlak 估计量AI 解读

We develop a new approach for estimating average treatment effects in observational studies with unobserved group-level heterogeneity. We consider a general model with group-level unconfoundedness and provide conditions under which aggregate balancing statistics -- group-level averages of functions of treatments and covariates -- are sufficient to eliminate differences between groups. Building on these results, we reinterpret commonly used linear fixed-effect regression…

极端分位数的因果分析：伦敦交通流应用AI 解读

Transport engineers employ various interventions to enhance traffic-network performance. Quantifying the impacts of Cycle Superhighways is complicated due to the non-random assignment of such an intervention over the transport network. Treatment effects on asymmetric and heavy-tailed distributions are better reflected at extreme tails rather than at the median. We propose a novel method to estimate the treatment effect at extreme tails incorporating heavy-tailed features in…

流行病学因果推断中的通用双重差分AI 解读

Difference-in-differences is undoubtedly one of the most widely used methods for evaluating the causal effect of an intervention in observational (i.e., nonrandomized) settings. The approach is typically used when pre- and post-exposure outcome measurements are available, and one can reasonably assume that the association of the unobserved confounder with the outcome has the same absolute magnitude in the two exposure arms, and is constant over time; a so-called parallel…

异质节点网络向量自回归模型的联合估计与分组识别AI 解读

Individuals or companies in a large social or financial network often display rather heterogeneous behaviors for various reasons. In this work, we propose a network vector autoregressive model with a latent group structure to model heterogeneous dynamic patterns observed from network nodes, for which group-wise network effects and timeinvariant fixed-effects can be naturally incorporated. In our framework, the model parameters and network node memberships can be…

校正幸存者偏差的可解释异质性治疗效应：出院后干预与再入院预防AI 解读

We used survival analysis to quantify the impact of postdischarge evaluation and management (E/M) services in preventing hospital readmission or death. Our approach avoids a specific pitfall of applying machine learning to this problem, which is an inflated estimate of the effect of interventions, due to survivors bias -- where the magnitude of inflation may be conditional on heterogeneous confounders in the population. This bias arises simply because in order to receive an…

多种间歇性治疗的因果效应估计及其新冠应用AI 解读

To draw real-world evidence about the comparative effectiveness of multiple time-varying treatments on patient survival, we develop a joint marginal structural survival model and a novel weighting strategy to account for time-varying confounding and censoring. Our methods formulate complex longitudinal treatments with multiple start/stop switches as the recurrent events with discontinuous intervals of treatment eligibility. We derive the weights in continuous time to handle…

有限因变量的双重差分与比率之比AI 解读

Difference in differences (DD) is widely used to find policy/treatment effects with observational data, but applying DD to limited dependent variables (LDV's) Y has been problematic. This paper addresses how to apply DD and related approaches (such as "ratio in ratios" or "ratio in odds ratios") to binary, count, fractional, multinomial or zero-censored Y under the unifying framework of `generalized linear models with link functions'. We evaluate DD and the related…

因果模型中最优干预设计的主动学习AI 解读

Sequential experimental design to discover interventions that achieve a desired outcome is a key problem in various domains including science, engineering and public policy. When the space of possible interventions is large, making an exhaustive search infeasible, experimental design strategies are needed. In this context, encoding the causal relationships between the variables, and thus the effect of interventions on the system, is critical for identifying desirable…