每日简报

利用异方差噪声模型识别患者特定的疾病根因AI 解读

Complex diseases are caused by a multitude of factors that may differ between patients even within the same diagnostic category. A few underlying root causes may nevertheless initiate the development of disease within each patient. We therefore focus on identifying patient-specific root causes of disease, which we equate to the sample-specific predictivity of the exogenous error terms in a structural equation model. We generalize from the linear setting to the…

因果推断不只是统计问题AI 解读

This paper introduces a collection of four data sets, similar to Anscombe's Quartet, that aim to highlight the challenges involved when estimating causal effects. Each of the four data sets is generated based on a distinct causal mechanism: the first involves a collider, the second involves a confounder, the third involves a mediator, and the fourth involves the induction of M-Bias by an included factor. The paper includes a mathematical summary of each data set, as well as…

弱识别函数的强识别泛函推断AI 解读

In a variety of applications, including nonparametric instrumental variable (NPIV) analysis, proximal causal inference under unmeasured confounding, and missing-not-at-random data with shadow variables, we are interested in inference on a continuous linear functional (e.g., average causal effects) of nuisance function (e.g., NPIV regression) defined by conditional moment restrictions. These nuisance functions are generally weakly identified, in that the conditional moment…

合成控制方法的设计视角AI 解读

Since their introduction in Abadie and Gardeazabal (2003), Synthetic Control (SC) methods have quickly become one of the leading methods for estimating causal effects in observational studies in settings with panel data. Formal discussions often motivate SC methods by the assumption that the potential outcomes were generated by a factor model. Here we study SC methods from a design-based perspective, assuming a model for the selection of the treated unit(s) and period(s). We…

以三维图像为中介的因果中介分析AI 解读

Causal mediation analysis is increasingly abundant in biology, psychology, and epidemiology studies, etc. In particular, with the advent of the big data era, the issue of high-dimensional mediators is becoming more prevalent. In neuroscience, with the widespread application of magnetic resonance technology in the field of brain imaging, studies on image being a mediator emerged. In this study, a novel causal mediation analysis method with a three-dimensional image mediator…

电子健康记录比较效果研究中信息性缺失数据的双重抽样AI 解读

Missing data arise in most applied settings and are ubiquitous in electronic health records (EHR). When data are missing not at random (MNAR) with respect to measured covariates, sensitivity analyses are often considered. These post-hoc solutions, however, are often unsatisfying in that they are not guaranteed to yield concrete conclusions. Motivated by an EHR-based study of long-term outcomes following bariatric surgery, we consider the use of double sampling as a means to…

基于回归秩得分的异质性分位数处理效应去偏推断AI 解读

Understanding treatment effect heterogeneity is vital to many scientific fields because the same treatment may affect different individuals differently. Quantile regression provides a natural framework for modeling such heterogeneity. We propose a new method for inference on heterogeneous quantile treatment effects in the presence of high-dimensional covariates. Our estimator combines an $\ell_1$-penalized regression adjustment with a quantile-specific bias correction scheme…

方差依赖界下渐近最优的固定预算最佳臂识别AI 解读

We investigate the problem of fixed-budget best arm identification (BAI) for minimizing expected simple regret. In an adaptive experiment, a decision maker draws one of multiple treatment arms based on past observations and observes the outcome of the drawn arm. After the experiment, the decision maker recommends the treatment arm with the highest expected outcome. We evaluate the decision based on the expected simple regret, which is the difference between the expected…

通过多层训练实现极小极大最优核算子学习AI 解读

Learning mappings between infinite-dimensional function spaces has achieved empirical success in many disciplines of machine learning, including generative modeling, functional data analysis, causal inference, and multi-agent reinforcement learning. In this paper, we study the statistical limit of learning a Hilbert-Schmidt operator between two infinite-dimensional Sobolev reproducing kernel Hilbert spaces. We establish the information-theoretic lower bound in terms of the…

有限与无限方差时间序列的时域长程依赖检测AI 解读

Empirical detection of long range dependence (LRD) of a time series often consists of deciding whether an estimate of the memory parameter $d$ corresponds to LRD. Surprisingly, the literature offers numerous spectral domain estimators for $d$ but there are only a few estimators in the time domain. Moreover, the latter estimators are criticized for relying on visual inspection to determine an observation window $[n_1, n_2]$ for a linear regression to run on. Theoretically…

通过协同学习实现近最优异方差回归AI 解读

We consider the problem of heteroscedastic linear regression, where, given $n$ samples $(\mathbf{x}_i, y_i)$ from $y_i = \langle \mathbf{w}^{*}, \mathbf{x}_i \rangle + ε_i \cdot \langle \mathbf{f}^{*}, \mathbf{x}_i \rangle$ with $\mathbf{x}_i \sim N(0,\mathbf{I})$, $ε_i \sim N(0,1)$, we aim to estimate $\mathbf{w}^{*}$. Beyond classical applications of such models in statistics, econometrics, time series analysis etc., it is also particularly relevant in machine learning…

含分类工具变量的不可忽略无应答数据：可核查识别条件AI 解读

We consider a model identification problem in which an outcome variable contains nonignorable missing values. Statistical inference requires a guarantee of the model identifiability to obtain estimators enjoying theoretically reasonable properties such as consistency and asymptotic normality. Recently, instrumental or shadow variables, combined with the completeness condition in the outcome model, have been highlighted to make a model identifiable. However, the completeness…

重尾分布极端分位数处理效应的估计与推断AI 解读

Causal inference for extreme events has many potential applications in fields such as climate science, medicine and economics. We study the extremal quantile treatment effect of a binary treatment on a continuous, heavy-tailed outcome. Existing methods are limited to the case where the quantile of interest is within the range of the observations. For applications in risk assessment, however, the most relevant cases relate to extremal quantiles that go beyond the data range.…

DRCFS：双重稳健因果特征选择AI 解读

Knowing the features of a complex system that are highly relevant to a particular target variable is of fundamental interest in many areas of science. Existing approaches are often limited to linear settings, sometimes lack guarantees, and in most cases, do not scale to the problem at hand, in particular to images. We propose DRCFS, a doubly robust feature selection method for identifying the causal features even in nonlinear and high dimensional settings. We provide…

金融预测中的专家聚合AI 解读

Machine learning algorithms dedicated to financial time series forecasting have gained a lot of interest. But choosing between several algorithms can be challenging, as their estimation accuracy may be unstable over time. Online aggregation of experts combine the forecasts of a finite set of models in a single approach without making any assumption about the models. In this paper, a Bernstein Online Aggregation (BOA) procedure is applied to the construction of long-short…

从混频观测恢复高频模型：单位根 VAR 的一般位置可识别性AI 解读

The "REtrieval from MIxed Sampling" (REMIS) approach based on blocking developed in Anderson et al. (2016a) is concerned with retrieving an underlying high frequency model from mixed frequency observations. In this paper we investigate parameter-identifiability in the Johansen (1995) vector error correction model for mixed frequency data. We prove that from the second moments of the blocked process after taking differences at lag N (N is the slow sampling rate), the…

有效的异方差稳健检验AI 解读

Tests based on heteroskedasticity robust standard errors are an important technique in econometric practice. Choosing the right critical value, however, is not simple at all: conventional critical values based on asymptotics often lead to severe size distortions; and so do existing adjustments including the bootstrap. To avoid these issues, we suggest to use smallest size-controlling critical values, the generic existence of which we prove in this article for the commonly…

粗糙波动率：事实还是测量假象？AI 解读

We investigate the statistical evidence for the use of `rough' fractional processes with Hurst exponent $H< 0.5$ for the modeling of volatility of financial assets, using a model-free approach. We introduce a non-parametric method for estimating the roughness of a function based on discrete sample, using the concept of normalized $p$-th variation along a sequence of partitions. We investigate the finite sample performance of our estimator for measuring the roughness of…

m 阶逆随机占优的非参数检验AI 解读

This paper proposes a nonparametric test for $m$th-degree inverse stochastic dominance which is a powerful tool for ranking distribution functions according to social welfare. We construct the test based on empirical process theory. The test is shown to be asymptotically size controlled and consistent. The good finite sample properties of the test are illustrated via Monte Carlo simulations. We apply our test to the inequality growth in the United Kingdom from 1995 to 2010.

新冠疫情期间利用含噪住院时间序列拟合 ICU 占床随机模型AI 解读

Intensive care occupancy is an important indicator of health care stress that has been used to guide policy decisions during the COVID-19 pandemic. Toward reliable decision-making as a pandemic progresses, estimating the rates at which patients are admitted to and discharged from hospitals and intensive care units (ICUs) is crucial. Since individual-level hospital data are rarely available to modelers in each geographic locality of interest, it is important to develop tools…

一般政策干预的无条件效应AI 解读

This paper studies the unconditional effects of a general policy intervention, which includes location-scale shifts and simultaneous shifts as special cases. The location-scale shift is intended to study a counterfactual policy aimed at changing not only the mean or location of a covariate but also its dispersion or scale. The simultaneous shift refers to the situation where shifts in two or more covariates take place simultaneously. For example, a shift in one covariate is…

改进重复测量混合模型以稳健提高随机试验精度AI 解读

In randomized trials, repeated measures of the outcome are routinely collected. The mixed model for repeated measures (MMRM) leverages the information from these repeated outcome measures, and is often used for the primary analysis to estimate the average treatment effect at the primary endpoint. MMRM, however, can suffer from bias and precision loss when it models intermediate outcomes incorrectly, and hence fails to use the post-randomization information harmlessly. This…

利用协变量调整伪值回归提高限制平均生存时间估计精度AI 解读

Covariate adjustment is desired by both practitioners and regulators of randomized clinical trials because it improves precision for estimating treatment effects. However, covariate adjustment presents a particular challenge in time-to-event analysis. We propose to apply covariate adjusted pseudovalue regression to estimate between-treatment difference in restricted mean survival times (RMST). Our proposed method incorporates a prognostic covariate to increase precision of…

高维白噪声的秩检验AI 解读

The development of high-dimensional white noise test is important in both statistical theories and applications, where the dimension of the time series can be comparable to or exceed the length of the time series. This paper proposes several distribution-free tests using the rank based statistics for testing the high-dimensional white noise, which are robust to the heavy tails and do not quire the finite-order moment assumptions for the sample distributions. Three families…