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政治学中的工具变量估计有多可信？基于六十余项复现的实践建议AI 解读

Instrumental variable (IV) strategies are widely used in political science to establish causal relationships. However, the identifying assumptions required by an IV design are demanding, and it remains challenging for researchers to assess their validity. In this paper, we replicate 67 papers published in three top journals in political science during 2010-2022 and identify several troubling patterns. First, researchers often overestimate the strength of their IVs due to…

风险比、优势比与风险差：哪种因果效应尺度更易推广？AI 解读

There are many measures to report so-called treatment or causal effects: absolute difference, ratio, odds ratio, number needed to treat, and so on. The choice of a measure, e.g. absolute versus relative, is often debated because it leads to different impressions of the benefit or risk of a treatment. Besides, different causal measures may lead to various treatment effect heterogeneity: some input variables may have an influence on some causal measures and no effect at all on…

不要求解唯一性的近端因果推断AI 解读

We consider identification and inference about a counterfactual outcome mean when there is unmeasured confounding using tools from proximal causal inference (Miao et al. [2018], Tchetgen Tchetgen et al. [2020]). Proximal causal inference requires existence of solutions to at least one of two integral equations. We motivate the existence of solutions to the integral equations from proximal causal inference by demonstrating that, assuming the existence of a solution to one of…

环境不变线性最小二乘AI 解读

This paper considers a multi-environment linear regression model in which data from multiple experimental settings are collected. The joint distribution of the response variable and covariates may vary across different environments, yet the conditional expectations of $y$ given the unknown set of important variables are invariant. Such a statistical model is related to the problem of endogeneity, causal inference, and transfer learning. The motivation behind it is…

依从者与不依从者平均因果效应中主层可忽略性违反的敏感性分析AI 解读

An important strategy for identifying principal causal effects, which are often used in settings with noncompliance, is to invoke the principal ignorability (PI) assumption. As PI is untestable, it is important to gauge how sensitive effect estimates are to its violation. We focus on this task for the common one-sided noncompliance setting where there are two principal strata, compliers and noncompliers. Under PI, compliers and noncompliers share the same…

饮酒对脑白质微结构完整性的影响：不完整表型数据的因果推断框架AI 解读

Although substance use, such as alcohol intake, is known to be associated with cognitive decline during aging, its direct influence on the central nervous system remains incompletely understood. In this study, we investigate the influence of alcohol intake frequency on reduction of brain white matter microstructural integrity in the fornix, a brain region considered a promising marker of age-related microstructural degeneration, using a large UK Biobank (UKB) cohort with…

无条件分位数效应的敏感性分析AI 解读

This paper proposes a framework to analyze the effects of counterfactual policies on the unconditional quantiles of an outcome variable. For a given counterfactual policy, we obtain identified sets for the effect of both marginal and global changes in the proportion of treated individuals. To conduct a sensitivity analysis, we introduce the quantile breakdown frontier, a curve that (i) indicates whether a sensitivity analysis is possible or not, and (ii) when a sensitivity…

通过神经 ADMG 学习进行潜在混杂下的因果推理AI 解读

Latent confounding has been a long-standing obstacle for causal reasoning from observational data. One popular approach is to model the data using acyclic directed mixed graphs (ADMGs), which describe ancestral relations between variables using directed and bidirected edges. However, existing methods using ADMGs are based on either linear functional assumptions or a discrete search that is complicated to use and lacks computational tractability for large datasets. In this…

学习业务流程的干预时机：结合因果推断与强化学习的处方性流程监控AI 解读

Increasing the success rate of a process, i.e. the percentage of cases that end in a positive outcome, is a recurrent process improvement goal. At runtime, there are often certain actions (a.k.a. treatments) that workers may execute to lift the probability that a case ends in a positive outcome. For example, in a loan origination process, a possible treatment is to issue multiple loan offers to increase the probability that the customer takes a loan. Each treatment has a…

提高平均处理效应跨人群迁移的估计效率AI 解读

We develop flexible, semiparametric estimators of the average treatment effect (ATE) transported to a new population ("target population") that offer potential efficiency gains. Transport may be of value when the ATE may differ across populations. We consider the setting where differences in the ATE are due to differences in the distribution of baseline covariates that modify the treatment effect ("effect modifiers"). First, we propose a collaborative one-step semiparametric…

只需询问两次：选择概率、事前收益与支付意愿的识别AI 解读

One of the exciting developments in the stated preference literature is the use of probabilistic stated preference experiments to estimate semi-parametric population distributions of ex ante returns and willingness-to-pay (WTP) for a choice attribute. This relies on eliciting several choices per individual, and estimating separate demand functions, at the cost of possibly long survey instruments. This paper shows that the distributions of interest can be recovered from at…

含大量控制变量的删失分位数回归AI 解读

This paper develops estimation and inference methods for censored quantile regression models with high-dimensional controls. The methods are based on the application of double/debiased machine learning (DML) framework to the censored quantile regression estimator of Buchinsky and Hahn (1998). I provide valid inference for low-dimensional parameters of interest in the presence of high-dimensional nuisance parameters when implementing machine learning estimators. The proposed…

半参数模型中未知参数方向的估计AI 解读

Semiparametric models are useful in econometrics, social sciences and medicine application. In this paper, a new estimator based on least square methods is proposed to estimate the direction of unknown parameters in semi-parametric models. The proposed estimator is consistent and has asymptotic distribution under mild conditions without the knowledge of the form of link function. Simulations show that the proposed estimator is significantly superior to maximum score…

目标最大似然估计在公共卫生与流行病学中的应用：系统综述AI 解读

The Targeted Maximum Likelihood Estimation (TMLE) statistical data analysis framework integrates machine learning, statistical theory, and statistical inference to provide a least biased, efficient and robust strategy for estimation and inference of a variety of statistical and causal parameters. We describe and evaluate the epidemiological applications that have benefited from recent methodological developments. We conducted a systematic literature review in PubMed for…

评估事件发生时间数据中治疗效应的非参数比例风险模型AI 解读

Time-to-event analysis often relies on prior parametric assumptions, or, if a non-parametric approach is chosen, Cox's model. This is inherently tied to the assumption of proportional hazards, with the analysis potentially invalidated if this assumption is not fulfilled. In addition, most interpretations focus on the hazard ratio, that is often misinterpreted as the relative risk. In this paper, we introduce an alternative to current methodology for assessing a treatment…

利用二元工具变量估计服从者期望短缺处理效应AI 解读

Estimating the causal effect of a treatment or exposure for a subpopulation is of great interest in many biomedical and economical studies. Expected shortfall, also referred to as the super-quantile, is an attractive effect-size measure that can accommodate data heterogeneity and aggregate local information of effect over a certain region of interest of the outcome distribution. In this article, we propose the ComplieR Expected Shortfall Treatment Effect (CRESTE) model under…

具有潜在分组结构的面板函数系数分位数回归AI 解读

This paper considers estimating functional-coefficient models in panel quantile regression with individual effects, allowing the cross-sectional and temporal dependence for large panel observations. A latent group structure is imposed on the heterogenous quantile regression models so that the number of nonparametric functional coefficients to be estimated can be reduced considerably. With the preliminary local linear quantile estimates of the subject-specific functional…

利用两个不完美工具变量点识别局部平均处理效应AI 解读

This paper characterizes point identification results of the local average treatment effect (LATE) using two imperfect instruments. The classical approach (Imbens and Angrist (1994)) establishes the identification of LATE via an instrument that satisfies exclusion, monotonicity, and independence. However, it may be challenging to find a single instrument that satisfies all these assumptions simultaneously. My paper uses two instruments but imposes weaker assumptions on both…

以三维图像为中介的因果中介分析AI 解读

Causal mediation analysis is increasingly abundant in biology, psychology, and epidemiology studies, etc. In particular, with the advent of the big data era, the issue of high-dimensional mediators is becoming more prevalent. In neuroscience, with the widespread application of magnetic resonance technology in the field of brain imaging, studies on image being a mediator emerged. In this study, a novel causal mediation analysis method with a three-dimensional image mediator…

预算约束下组合治疗的最优个体化规则AI 解读

The individualized treatment rule (ITR), which recommends an optimal treatment based on individual characteristics, has drawn considerable interest from many areas such as precision medicine, personalized education, and personalized marketing. Existing ITR estimation methods mainly adopt one of two or more treatments. However, a combination of multiple treatments could be more powerful in various areas. In this paper, we propose a novel Double Encoder Model (DEM) to estimate…

加性噪声模型中寻找因果顺序的尺度不变排序准则AI 解读

Additive Noise Models (ANMs) are a common model class for causal discovery from observational data and are often used to generate synthetic data for causal discovery benchmarking. Specifying an ANM requires choosing all parameters, including those not fixed by explicit assumptions. Reisach et al. (2021) show that sorting variables by increasing variance often yields an ordering close to a causal order and introduce var-sortability to quantify this alignment. Since increasing…

厘清整群随机试验中的估计目标AI 解读

Estimands can help clarify the interpretation of treatment effects and ensure that estimators are aligned to the study's objectives. Cluster randomised trials require additional attributes to be defined within the estimand compared to individually randomised trials, including whether treatment effects are marginal or cluster specific, and whether they are participant or cluster average. In this paper, we provide formal definitions of estimands encompassing both these…

lmw：用于因果推断的线性模型权重AI 解读

The linear regression model is widely used in the biomedical and social sciences as well as in policy and business research to adjust for covariates and estimate the average effects of treatments. Behind every causal inference endeavor there is a hypothetical randomized experiment. However, in routine regression analyses in observational studies, it is unclear how well the adjustments made by regression approximate key features of randomized experiments, such as covariate…

准确估计因果效应时的超参数调优挑战AI 解读

ML is playing an increasingly crucial role in estimating causal effects of treatments on outcomes from observational data. Many ML methods (`causal estimators') have been proposed for this task. All of these methods, as with any ML approach, require extensive hyperparameter tuning. For non-causal predictive tasks, there is a consensus on the choice of tuning metrics (e.g. mean squared error), making it simple to compare models. However, for causal inference tasks, such a…