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多研究数据的因子分析高斯图模型估计AI 解读

Network models are powerful tools for gaining new insights from complex biological data. Most lines of investigation in biology involve comparing datasets in the setting where the same predictors are measured across multiple studies or conditions (multi-study data). Consequently, the development of statistical tools for network modeling of multi-study data is a highly active area of research. Multi-study factor analysis (MSFA) is a method for estimation of latent variables…

基于贝叶斯加性回归树的灵活工具变量模型AI 解读

Methods utilizing instrumental variables have been a fundamental statistical approach to estimation in the presence of unmeasured confounding, usually occurring in non-randomized observational data common to fields such as economics and public health. However, such methods usually make constricting linearity and additivity assumptions that are inapplicable to the complex modeling challenges of today. The growing body of observational data being collected will necessitate…

右删失生存数据中的断点回归设计AI 解读

In this paper the regression discontinuity design is adapted to the survival analysis setting with right-censored data, studied in an intensity based counting process framework. In particular, a local polynomial regression version of the Aalen additive hazards estimator is introduced as an estimator of the difference between two covariate dependent cumulative hazard rate functions. Large-sample theory for this estimator is developed, including confidence intervals that take…

利用模型森林估计观测数据的异质性处理效应AI 解读

The estimation of heterogeneous treatment effects (HTEs) has attracted considerable interest in many disciplines, most prominently in medicine and economics. Contemporary research has so far primarily focused on continuous and binary responses where HTEs are traditionally estimated by a linear model, which allows the estimation of constant or heterogeneous effects even under certain model misspecifications. More complex models for survival, count, or ordinal outcomes require…

利用次序统计量识别拍卖中的未观测异质性AI 解读

We establish nonparametric identification of auction models with continuous and nonseparable unobserved heterogeneity using three consecutive order statistics of bids. We then propose sieve maximum likelihood estimators for the joint distribution of unobserved heterogeneity and the private value, as well as their conditional and marginal distributions. Lastly, we apply our methodology to a novel dataset from judicial auctions in China. Our estimates suggest substantial gains…

聚类观测研究的因果匹配估计：海洋保护区与生物多样性AI 解读

Marine conservation preserves fish biodiversity, protects marine and coastal ecosystems, and supports climate resilience and adaptation. Despite the importance of establishing marine protected areas (MPAs), research on the effectiveness of MPAs with different conservation policies is limited due to the lack of quantitative MPA information. In this paper, leveraging a global MPA database, we investigate the causal impact of MPA policies on fish biodiversity. To address…

边际结构模型的敏感性分析AI 解读

We introduce several methods for assessing sensitivity to unmeasured confounding in marginal structural models; importantly we allow treatments to be discrete or continuous, static or time-varying. We consider three sensitivity models: a propensity-based model, an outcome-based model, and a subset confounding model, in which only a fraction of the population is subject to unmeasured confounding. In each case we develop efficient estimators and confidence intervals for bounds…

潜在结构因果模型的学习AI 解读

Causal learning has long concerned itself with the accurate recovery of underlying causal mechanisms. Such causal modelling enables better explanations of out-of-distribution data. Prior works on causal learning assume that the high-level causal variables are given. However, in machine learning tasks, one often operates on low-level data like image pixels or high-dimensional vectors. In such settings, the entire Structural Causal Model (SCM) -- structure, parameters,…

用于电子健康记录因果推断的动态生存 TransformerAI 解读

In medicine, researchers often seek to infer the effects of a given treatment on patients' outcomes. However, the standard methods for causal survival analysis make simplistic assumptions about the data-generating process and cannot capture complex interactions among patient covariates. We introduce the Dynamic Survival Transformer (DynST), a deep survival model that trains on electronic health records (EHRs). Unlike previous transformers used in survival analysis, DynST can…

改进随机对照试验数据中的增益模型评估AI 解读

Estimating treatment effects is one of the most challenging and important tasks of data analysts. In many applications, like online marketing and personalized medicine, treatment needs to be allocated to the individuals where it yields a high positive treatment effect. Uplift models help select the right individuals for treatment and maximize the overall treatment effect (uplift). A major challenge in uplift modeling concerns model evaluation. Previous literature suggests…

协变量调整回归函数的去偏推断AI 解读

In this article, we study nonparametric inference for a covariate-adjusted regression function. This parameter captures the average association between a continuous exposure and an outcome after adjusting for other covariates. In particular, under certain causal conditions, this parameter corresponds to the average outcome had all units been assigned to a specific exposure level, known as the causal dose-response curve. We propose a debiased local linear estimator of the…

重叠权重、匹配权重与熵权重：究竟在估计什么？AI 解读

There has been a recent surge in statistical methods for handling the lack of adequate positivity when using inverse probability weights (IPW). However, these nascent developments have raised a number of questions. Thus, we demonstrate the ability of equipoise estimators (overlap, matching, and entropy weights) to handle the lack of positivity. Compared to IPW, the equipoise estimators have been shown to be flexible and easy to interpret. However, promoting their wide use…

边际结构分位数模型的双重稳健估计与敏感性分析AI 解读

The marginal structure quantile model (MSQM) provides a unique lens to understand the causal effect of a time-varying treatment on the full distribution of potential outcomes. Under the semiparametric framework, we derive the efficiency influence function for the MSQM, from which a new doubly robust estimator is proposed for point estimation and inference. We show that the doubly robust estimator is consistent if either of the models associated with treatment assignment or…

高维状态空间中具有有限时间保证的马尔可夫决策过程结构估计AI 解读

We consider the task of estimating a structural model of dynamic decisions by a human agent based upon the observable history of implemented actions and visited states. This problem has an inherent nested structure: in the inner problem, an optimal policy for a given reward function is identified while in the outer problem, a measure of fit is maximized. Several approaches have been proposed to alleviate the computational burden of this nested-loop structure, but these…

异质性面板中的个体平均估计AI 解读

In this work we introduce a unit averaging procedure to efficiently recover unit-specific parameters in a heterogeneous panel model. The procedure consists in estimating the parameter of a given unit using a weighted average of all the unit-specific parameter estimators in the panel. The weights of the average are determined by minimizing an MSE criterion we derive. We analyze the properties of the resulting minimum MSE unit averaging estimator in a local heterogeneity…

情境赌博机的任意时刻有效离策略推断AI 解读

Contextual bandit algorithms are ubiquitous tools for active sequential experimentation in healthcare and the tech industry. They involve online learning algorithms that adaptively learn policies over time to map observed contexts $X_t$ to actions $A_t$ in an attempt to maximize stochastic rewards $R_t$. This adaptivity raises interesting but hard statistical inference questions, especially counterfactual ones: for example, it is often of interest to estimate the properties…

如何抽样与何时停止：广义 Wald 问题及极小极大策略AI 解读

We study sequential experiments where sampling is costly and a decision-maker aims to determine the best treatment for full scale implementation by (1) adaptively allocating units between two possible treatments, and (2) stopping the experiment when the expected welfare (inclusive of sampling costs) from implementing the chosen treatment is maximized. Working under a continuous time limit, we characterize the optimal policies under the minimax regret criterion. We show that…

干扰程度：存在干扰时因果推断的一般框架AI 解读

One core assumption typically adopted for valid causal inference is that of no interference between experimental units, i.e., the outcome of an experimental unit is unaffected by the treatments assigned to other experimental units. This assumption can be violated in real-life experiments, which significantly complicates the task of causal inference. As the number of potential outcomes increases, it becomes challenging to disentangle direct treatment effects from…

随机实验中的“少数者支配”回归调整AI 解读

Regression adjustment is widely used for the analysis of randomized experiments to improve the estimation efficiency of the treatment effect. This paper reexamines a weighted regression adjustment method termed as tyranny-of-the-minority (ToM), wherein units in the minority group are given greater weights. We demonstrate that the ToM regression adjustment is more robust than Lin 2013's regression adjustment with treatment-covariate interactions, even though these two…

重叠不足时用平衡权重估计已处理者的处理效应AI 解读

Inverse probability weights are commonly used in epidemiology to estimate causal effects in observational studies. Researchers can typically focus on either the average treatment effect or the average treatment effect on the treated with inverse probability weighting estimators. However, when overlap between the treated and control groups is poor, this can produce extreme weights that can result in biased estimates and large variances. One alternative to inverse probability…

随机实验中回归调整的统一分析AI 解读

Regression adjustment is broadly applied in randomized trials under the premise that it usually improves the precision of a treatment effect estimator. However, previous work has shown that this is not always true. To further understand this phenomenon, we develop a unified comparison of the asymptotic variance of a class of linear regression-adjusted estimators. Our analysis is based on the classical theory for linear regression with heteroscedastic errors and thus does not…

用于后门与前门调整的神经均值嵌入方法AI 解读

We consider the estimation of average and counterfactual treatment effects, under two settings: back-door adjustment and front-door adjustment. The goal in both cases is to recover the treatment effect without having an access to a hidden confounder. This objective is attained by first estimating the conditional mean of the desired outcome variable given relevant covariates (the "first stage" regression), and then taking the (conditional) expectation of this function as a…

从连续时间动力学模型中挖掘因果结构：海啸预测应用AI 解读

Continuous-time dynamics models, such as neural ordinary differential equations, have enabled the modeling of underlying dynamics in time-series data and accurate forecasting. However, parameterization of dynamics using a neural network makes it difficult for humans to identify causal structures in the data. In consequence, this opaqueness hinders the use of these models in the domains where capturing causal relationships carries the same importance as accurate predictions,…

从多元函数型数据发现因果关系的函数型贝叶斯网络AI 解读

Multivariate functional data arise in a wide range of applications. One fundamental task is to understand the causal relationships among these functional objects of interest, which has not yet been fully explored. In this article, we develop a novel Bayesian network model for multivariate functional data where the conditional independence and causal structure are both encoded by a directed acyclic graph. Specifically, we allow the functional objects to deviate from Gaussian…