每日简报

基于二元时间序列的期望最大化网络重构及适用网络类型AI 解读

Based on the binary time series data of social infection dynamics, we propose a general framework to reconstruct 2-simplex complexes with two-body and three-body interactions by combining the maximum likelihood estimation in statistical inference and introducing the expectation maximization. In order to improve the code running efficiency, the whole algorithm adopts vectorization expression. Through the inference of maximum likelihood estimation, the vectorization expression…

不同变量范式下深度学习因果发现的综述与路线图AI 解读

Understanding causality helps to structure interventions to achieve specific goals and enables predictions under interventions. With the growing importance of learning causal relationships, causal discovery tasks have transitioned from using traditional methods to infer potential causal structures from observational data to the field of pattern recognition involved in deep learning. The rapid accumulation of massive data promotes the emergence of causal search methods with…

结合变分因果推断与细化关系信息预测细胞响应AI 解读

Predicting the responses of a cell under perturbations may bring important benefits to drug discovery and personalized therapeutics. In this work, we propose a novel graph variational Bayesian causal inference framework to predict a cell's gene expressions under counterfactual perturbations (perturbations that this cell did not factually receive), leveraging information representing biological knowledge in the form of gene regulatory networks (GRNs) to aid individualized…

混杂马尔可夫决策过程中的工具变量离线强化学习AI 解读

We study the offline reinforcement learning (RL) in the face of unmeasured confounders. Due to the lack of online interaction with the environment, offline RL is facing the following two significant challenges: (i) the agent may be confounded by the unobserved state variables; (ii) the offline data collected a prior does not provide sufficient coverage for the environment. To tackle the above challenges, we study the policy learning in the confounded MDPs with the aid of…

微生物组数据中组成型中介效应选择的贝叶斯联合模型AI 解读

Analyzing multivariate count data generated by high-throughput sequencing technology in microbiome research studies is challenging due to the high-dimensional and compositional structure of the data and overdispersion. In practice, researchers are often interested in investigating how the microbiome may mediate the relation between an assigned treatment and an observed phenotypic response. Existing approaches designed for compositional mediation analysis are unable to…

含交互固定效应的线性多维回归AI 解读

This paper studies a linear model for multidimensional panel data of three or more dimensions with unobserved interactive fixed-effects. The main estimator uses a Neyman-orthogonal approach, and requires two preliminary steps. First, the model is embedded within a two-dimensional panel framework where factor model methods in Bai (2009) lead to consistent, but slowly converging, estimates. The second step develops a weighted-within transformation that is robust to…

改进的因果森林AI 解读

Uncovering the heterogeneity of causal effects of policies and business decisions at various levels of granularity provides substantial value to decision makers. This paper develops estimation and inference procedures for multiple treatment models in a selection-on-observed-variables framework by modifying the Causal Forest approach (Wager and Athey, 2018) in several dimensions. The new estimators have desirable theoretical, computational, and practical properties for…

处理水平可增长且组规模不同时设计型因果推断的 Berry–Esseen 界AI 解读

Neyman (1923/1990) introduced the randomization model, which contains the notation of potential outcomes to define causal effects and a framework for large-sample inference based on the design of the experiment. However, the existing theory for this framework is far from complete, especially when the number of treatment levels diverges and the treatment group sizes vary. We provide a unified discussion of statistical inference under the randomization model with general…

无序多值处理的工具变量：理论与专业学习收益证据AI 解读

We revisit the identification argument of Kirkeboen et al. (2016) who showed how one may combine instruments for multiple unordered treatments with information about individuals' ranking of these treatments to achieve identification while allowing for both observed and unobserved heterogeneity in treatment effects. We show that the key assumptions underlying their identification argument have testable implications. We also provide a new characterization of the bias that may…

通过最优标签置换分类进行类别数据的二元因果发现AI 解读

Causal discovery for quantitative data has been extensively studied but less is known for categorical data. We propose a novel causal model for categorical data based on a new classification model, termed classification with optimal label permutation (COLP). By design, COLP is a parsimonious classifier, which gives rise to a provably identifiable causal model. A simple learning algorithm via comparing likelihood functions of causal and anti-causal models suffices to learn…

利用GWAS汇总数据推断非线性因果效应AI 解读

Large-scale genome-wide association studies (GWAS) have offered an exciting opportunity to discover putative causal genes or risk factors associated with diseases by using SNPs as instrumental variables (IVs). However, conventional approaches assume linear causal relations partly for simplicity and partly for the availability of GWAS summary data. In this work, we propose a novel model {for transcriptome-wide association studies (TWAS)} to incorporate nonlinear relationships…

样本选择下异质性治疗效应的界：社交媒体与政治极化应用AI 解读

We propose a method for estimation and inference for bounds for heterogeneous causal effect parameters in general sample selection models where the treatment can affect whether an outcome is observed and no exclusion restrictions are available. The method provides conditional effect bounds as functions of policy relevant pre-treatment variables. It allows for conducting valid statistical inference on the unidentified conditional effects. We use a flexible debiased/double…

异质节点网络向量自回归模型的联合估计与分组识别AI 解读

Individuals or companies in a large social or financial network often display rather heterogeneous behaviors for various reasons. In this work, we propose a network vector autoregressive model with a latent group structure to model heterogeneous dynamic patterns observed from network nodes, for which group-wise network effects and timeinvariant fixed-effects can be naturally incorporated. In our framework, the model parameters and network node memberships can be…

极端连续处理效应：度量、估计与推断AI 解读

This paper concerns estimation and inference for treatment effects in deep tails of the counterfactual distribution of unobservable potential outcomes corresponding to a continuously valued treatment. We consider two measures for the deep tail characteristics: the extreme quantile function and the tail mean function defined as the conditional mean beyond a quantile level. Then we define the extreme quantile treatment effect (EQTE) and the extreme average treatment effect…

因果推断框架综述AI 解读

Causal inference is a science with multi-disciplinary evolution and applications. On the one hand, it measures effects of treatments in observational data based on experimental designs and rigorous statistical inference to draw causal statements. One of the most influential framework in quantifying causal effects is the potential outcomes framework. On the other hand, causal graphical models utilizes directed edges to represent causalities and encodes conditional…

利用效用异质的替代标记检验处理效应AI 解读

The primary benefit of identifying a valid surrogate marker is the ability to use it in a future trial to test for a treatment effect with shorter follow-up time or less cost. However, previous work has demonstrated potential heterogeneity in the utility of a surrogate marker. When such heterogeneity exists, existing methods that use the surrogate to test for a treatment effect while ignoring this heterogeneity may lead to inaccurate conclusions about the treatment effect,…

优化替代标记的使用以提高检验功效AI 解读

Motivated by increasing pressure for decision makers to shorten the time required to evaluate the efficacy of a treatment such that treatments deemed safe and effective can be made publicly available, there has been substantial recent interest in using an earlier or easier to measure surrogate marker, $S$, in place of the primary outcome, $Y$. To validate the utility of a surrogate marker in these settings, a commonly advocated measure is the proportion of treatment effect…

疫情期间多伦多家庭配送频率建模与网购诱发出行需求AI 解读

The COVID-19 pandemic dramatically catalyzed the proliferation of e-shopping. The dramatic growth of e-shopping will undoubtedly cause significant impacts on travel demand. As a result, transportation modeller's ability to model e-shopping demand is becoming increasingly important. This study developed models to predict household' weekly home delivery frequencies. We used both classical econometric and machine learning techniques to obtain the best model. It is found that…

未测混杂下处理效应的模型辅助敏感性分析与正则化校准估计AI 解读

Consider sensitivity analysis for estimating average treatment effects under unmeasured confounding, assumed to satisfy a marginal sensitivity model. At the population level, we provide new representations for the sharp population bounds and doubly robust estimating functions, recently derived by Dorn, Guo, and Kallus. We also derive new, relaxed population bounds, depending on weighted linear outcome quantile regression. At the sample level, we develop new methods and…

以测试分数为运行变量的局部随机化断点回归设计AI 解读

Explanations of the internal validity of regression discontinuity designs (RDD) generally appeal to the idea that RDDs are ``as good as" random near the treatment cut point. Cattaneo, Frandsen, and Titiunik (2015) are the first to take this justification to its full conclusion and propose estimating the RDD local average treatment effect (LATE) the same as one would a randomized experiment. This paper explores the implications of analyzing an RDD as a local random experiment…

裂区设计中的再随机化与协变量调整AI 解读

The split-plot design arises from agricultural sciences with experimental units, also known as subplots, nested within groups known as whole plots. It assigns the whole-plot intervention by a cluster randomization at the whole-plot level and assigns the subplot intervention by a stratified randomization at the subplot level. The randomization mechanism guarantees covariate balance on average at both the whole-plot and subplot levels, and ensures consistent inference of the…

非参数模型下分回合部分可观测马尔可夫决策过程的离策略评估AI 解读

We study the problem of off-policy evaluation (OPE) for episodic Partially Observable Markov Decision Processes (POMDPs) with continuous states. Motivated by the recently proposed proximal causal inference framework, we develop a non-parametric identification result for estimating the policy value via a sequence of so-called V-bridge functions with the help of time-dependent proxy variables. We then develop a fitted-Q-evaluation-type algorithm to estimate V-bridge functions…

用于干预后密度估计的归一化流AI 解读

Existing machine learning methods for causal inference usually estimate quantities expressed via the mean of potential outcomes (e.g., average treatment effect). However, such quantities do not capture the full information about the distribution of potential outcomes. In this work, we estimate the density of potential outcomes after interventions from observational data. For this, we propose a novel, fully-parametric deep learning method called Interventional Normalizing…

因果模型中最优干预设计的主动学习AI 解读

Sequential experimental design to discover interventions that achieve a desired outcome is a key problem in various domains including science, engineering and public policy. When the space of possible interventions is large, making an exhaustive search infeasible, experimental design strategies are needed. In this context, encoding the causal relationships between the variables, and thus the effect of interventions on the system, is critical for identifying desirable…