每日简报

极端分位数回归神经网络及其洪水风险预测应用AI 解读

Risk assessment for extreme events requires accurate estimation of high quantiles that go beyond the range of historical observations. When the risk depends on the values of observed predictors, regression techniques are used to interpolate in the predictor space. We propose the EQRN model that combines tools from neural networks and extreme value theory into a method capable of extrapolation in the presence of complex predictor dependence. Neural networks can naturally…

分布式数据上的协作因果推断AI 解读

In recent years, the development of technologies for causal inference with privacy preservation of distributed data has gained considerable attention. Many existing methods for distributed data focus on resolving the lack of subjects (samples) and can only reduce random errors in estimating treatment effects. In this study, we propose a data collaboration quasi-experiment (DC-QE) that resolves the lack of both subjects and covariates, reducing random errors and biases in the…

D-BIAS：基于因果模型的人机协同算法偏差治理系统AI 解读

With the rise of AI, algorithms have become better at learning underlying patterns from the training data including ingrained social biases based on gender, race, etc. Deployment of such algorithms to domains such as hiring, healthcare, law enforcement, etc. has raised serious concerns about fairness, accountability, trust and interpretability in machine learning algorithms. To alleviate this problem, we propose D-BIAS, a visual interactive tool that embodies…

利用逆概率加权回归调整双重稳健估计局部平均处理效应AI 解读

We revisit the problem of estimating the local average treatment effect (LATE) and the local average treatment effect on the treated (LATT) when control variables are available, either to render the instrumental variable (IV) suitably exogenous or to improve precision. Unlike previous approaches, our doubly robust (DR) estimation procedures use quasi-likelihood methods weighted by the inverse of the IV propensity score - so-called inverse probability weighted regression…

选择条件工具变量集合的图形工具AI 解读

We consider the efficient estimation of total causal effects in the presence of unmeasured confounding using conditional instrumental sets. Specifically, we consider the two-stage least squares estimator in the setting of a linear structural equation model with correlated errors that is compatible with a known acyclic directed mixed graph. To set the stage for our results, we characterize the class of linearly valid conditional instrumental sets that yield consistent…

个体随机化设计下利用邻域干扰的低阶交互结构AI 解读

Network interference, where the outcome of an individual is affected by the treatment assignment of those in their social network, is pervasive in real-world settings. However, it poses a challenge to estimating causal effects. We consider the task of estimating the total treatment effect (TTE), or the difference between the average outcomes of the population when everyone is treated versus when no one is, under network interference. Under a Bernoulli randomized design, we…

早期肿瘤试验混合对照方法评估：基于MORPHEUS-UC的模拟研究AI 解读

Phase Ib/II oncology trials, despite their small sample sizes, aim to provide information for optimal internal company decision-making concerning novel drug development. Hybrid controls (a combination of the current control arm and controls from one or more sources of historical trial data [HTD]) can be used to increase the statistical precision. Here we assess combining two sources of Roche HTD to construct a hybrid control in targeted therapy for decision-making via an…

基于 assurance 的两组整群随机试验贝叶斯设计与分析AI 解读

We consider the design of a two-arm superiority cluster randomised controlled trial (RCT) with a continuous outcome. We detail Bayesian inference for the analysis of the trial using a linear mixed-effects model. The treatment is compared to control using the posterior distribution for the treatment effect. We develop the form of the assurance to choose the sample size based on this analysis, and its evaluation using a two loop Monte Carlo sampling scheme. We assess the…

抵御混杂影响的稳健因果图表示学习AI 解读

The prevailing graph neural network models have achieved significant progress in graph representation learning. However, in this paper, we uncover an ever-overlooked phenomenon: the pre-trained graph representation learning model tested with full graphs underperforms the model tested with well-pruned graphs. This observation reveals that there exist confounders in graphs, which may interfere with the model learning semantic information, and current graph representation…

多阈值断点回归设计下的安全政策学习AI 解读

The regression discontinuity (RD) design is widely used for program evaluation with observational data. The primary focus of the existing literature has been the estimation of the local average treatment effect at the existing treatment cutoff. In contrast, we consider policy learning under the RD design. Because the treatment assignment mechanism is deterministic, learning better treatment cutoffs requires extrapolation. We develop a robust optimization approach to finding…

模型孪生随机化：重复个体处理效应的估计AI 解读

Temporally dense single-person "small data" have become widely available thanks to mobile apps and wearable sensors. Many caregivers and self-trackers want to use these data to help a specific person change their behavior to achieve desired health outcomes. Ideally, this involves discerning possible causes from correlations using that person's own observational time series data. In this paper, we estimate within-individual average treatment effects of physical activity on…

通过预测值进行预测：预判预测的施为效应AI 解读

Predictions about people, such as their expected educational achievement or their credit risk, can be performative and shape the outcome that they aim to predict. Understanding the causal effect of these predictions on the eventual outcomes is crucial for foreseeing the implications of future predictive models and selecting which models to deploy. However, this causal estimation task poses unique challenges: model predictions are usually deterministic functions of input…

依赖删失下的工具变量方法AI 解读

This paper considers the problem of inferring the causal effect of a variable $Z$ on a dependently censored survival time $T$. We allow for unobserved confounding variables, such that the error term of the regression model for $T$ is correlated with the confounded variable $Z$. Moreover, $T$ is subject to dependent censoring. This means that $T$ is right censored by a censoring time $C$, which is dependent on $T$ (even after conditioning out the effects of the measured…

利用二元工具变量在未观测混杂下估计个体处理效应AI 解读

Estimating conditional average treatment effects (CATEs) from observational data is relevant in many fields such as personalized medicine. However, in practice, the treatment assignment is usually confounded by unobserved variables and thus introduces bias. A remedy to remove the bias is the use of instrumental variables (IVs). Such settings are widespread in medicine (e.g., trials where the treatment assignment is used as binary IV). In this paper, we propose a novel,…

结合外部观测数据识别与估计临床试验长期处理效应AI 解读

In biomedical studies, estimating drug effects on chronic diseases requires a long follow-up period, which is difficult to meet in randomized clinical trials (RCTs). The use of a short-term surrogate to replace the long-term outcome for assessing the drug effect relies on stringent assumptions that empirical studies often fail to satisfy. Motivated by a kidney disease study, we investigate the drug effects on long-term outcomes by combining an RCT without observation of…

存在干扰参数时模型不完备性的稳健检验AI 解读

Economic models may exhibit incompleteness depending on whether or not they admit certain policy-relevant features such as strategic interaction, self-selection, or state dependence. We develop a novel test of model incompleteness and analyze its asymptotic properties. A key observation is that one can identify the least-favorable parametric model that represents the most challenging scenario for detecting local alternatives without knowledge of the selection mechanism. We…

弱工具变量、第一阶段异方差、稳健 F 检验与基于第一阶段残差的 GMMAI 解读

This paper is concerned with the findings related to the robust first-stage F-statistic in the Monte Carlo analysis of Andrews (2018), who found in a heteroskedastic grouped-data design that even for very large values of the robust F-statistic, the standard 2SLS confidence intervals had large coverage distortions. This finding appears to discredit the robust F-statistic as a test for underidentification. However, it is shown here that large values of the robust F-statistic…

处理状态误分类下的双重差分AI 解读

This paper studies identification and estimation of the average treatment effect on the treated (ATT) in difference-in-difference (DID) designs when the variable that classifies individuals into treatment and control groups (treatment status, D) is endogenously misclassified. We show that misclassification in D hampers consistent estimation of ATT because 1) it restricts us from identifying the truly treated from those misclassified as being treated and 2) differential…

重审倾向得分的核心作用：连接因果机器学习中的平衡与效率AI 解读

About forty years ago, in a now--seminal contribution, Rosenbaum & Rubin (1983) introduced a critical characterization of the propensity score as a central quantity for drawing causal inferences in observational study settings. In the decades since, much progress has been made across several research fronts in causal inference, notably including the re-weighting and matching paradigms. Focusing on the former and specifically on its intersection with machine learning and…

加权估计的方差型敏感性分析与更具信息量的界限AI 解读

Weighting methods are popular tools for estimating causal effects; assessing their robustness under unobserved confounding is important in practice. In the following paper, we introduce a new set of sensitivity models called "variance-based sensitivity models". Variance-based sensitivity models characterize the bias from omitting a confounder by bounding the distributional differences that arise in the weights from omitting a confounder, with several notable innovations over…

G 估计量对无效工具变量的敏感性分析AI 解读

Instrumental variables regression is a tool that is commonly used in the analysis of observational data. The instrumental variables are used to make causal inference about the effect of a certain exposure in the presence of unmeasured confounders. A valid instrumental variable is a variable that is associated with the exposure, affects the outcome only through the exposure (exclusion criterion), and is not confounded with the outcome (exogeneity). These assumptions are…

随机试验重加权推广：有限样本误差与变量选择AI 解读

Randomized Controlled Trials (RCTs) may suffer from limited scope. In particular, samples may be unrepresentative: some RCTs over- or under- sample individuals with certain characteristics compared to the target population, for which one wants conclusions on treatment effectiveness. Re-weighting trial individuals to match the target population can improve the treatment effect estimation. In this work, we establish the exact expressions of the bias and variance of such…

因果发现之后的有效推断AI 解读

Causal discovery and causal effect estimation are two fundamental tasks in causal inference. While many methods have been developed for each task individually, statistical challenges arise when applying these methods jointly: estimating causal effects after running causal discovery algorithms on the same data leads to "double dipping," invalidating the coverage guarantees of classical confidence intervals. To this end, we develop tools for valid post-causal-discovery…

弱识别函数的强识别泛函推断AI 解读

In a variety of applications, including nonparametric instrumental variable (NPIV) analysis, proximal causal inference under unmeasured confounding, and missing-not-at-random data with shadow variables, we are interested in inference on a continuous linear functional (e.g., average causal effects) of nuisance function (e.g., NPIV regression) defined by conditional moment restrictions. These nuisance functions are generally weakly identified, in that the conditional moment…