每日简报

调整生存曲线混杂因素的不同方法比较AI 解读

Treatment specific survival curves are an important tool to illustrate the treatment effect in studies with time-to-event outcomes. In non-randomized studies, unadjusted estimates can lead to biased depictions due to confounding. Multiple methods to adjust survival curves for confounders exist. However, it is currently unclear which method is the most appropriate in which situation. Our goal is to compare forms of Inverse Probability of Treatment Weighting, the G-Formula,…

回归模型中的对数与零值问题AI 解读

The log transformation is widely used in linear regression, mainly because coefficients are interpretable as proportional effects. Yet this practice has fundamental limitations, most notably that the log is undefined at zero, creating an identification problem. We propose a new estimator, iterated OLS (iOLS), which targets the normalized average treatment effect, preserving the percentage-change interpretation while addressing these limitations. Our procedure is the…

将因果推断引入节能建筑设计过程AI 解读

"What-if" questions are intuitively generated and commonly asked during the design process. Engineers and architects need to inherently conduct design decisions, progressing from one phase to another. They either use empirical domain experience, simulations, or data-driven methods to acquire consequential feedback. We take an example from an interdisciplinary domain of energy-efficient building design to argue that the current methods for decision support have limitations or…

重复测量进展模型：估计进行性疾病的新型治疗效应AI 解读

Mixed Models for Repeated Measures (MMRMs) are ubiquitous when analyzing outcomes of clinical trials. However, the linearity of the fixed-effect structure in these models largely restrict their use to estimating treatment effects that are defined as linear combinations of effects on the outcome scale. In some situations, alternative quantifications of treatment effects may be more appropriate. In progressive diseases, for example, one may want to estimate if a drug has…

半参数双重稳健目标化双重机器学习综述AI 解读

In this review we cover the basics of efficient nonparametric parameter estimation (also called functional estimation), with a focus on parameters that arise in causal inference problems. We review both efficiency bounds (i.e., what is the best possible performance for estimating a given parameter?) and the analysis of particular estimators (i.e., what is this estimator's error, and does it attain the efficiency bound?) under weak assumptions. We emphasize minimax-style…

利用网络元回归综合跨研究设计证据与跨格式数据AI 解读

In network meta-analysis (NMA), we synthesize all relevant evidence about health outcomes with competing treatments. The evidence may come from randomized controlled trials (RCT) or non-randomized studies (NRS) as individual participant data (IPD) or as aggregate data (AD). We present a suite of Bayesian NMA and network meta-regression (NMR) models allowing for cross-design and cross-format synthesis. The models integrate a three-level hierarchical model for synthesizing IPD…

合成控制的实践应用AI 解读

In this article we propose a set of simple principles to guide empirical practice in synthetic control studies. The proposed principles follow from formal properties of synthetic control estimators, and pertain to the nature, implications, and prevention of over-fitting biases within a synthetic control framework, to the interpretability of the results, and to the availability of validation exercises. We discuss and visually demonstrate the relevance of the proposed…

什么是随机化检验？AI 解读

The meaning of randomization tests has become obscure in statistics education and practice over the last century. This article makes a fresh attempt at rectifying this core concept of statistics. A new term -- "quasi-randomization test" -- is introduced to define significance tests based on theoretical models and distinguish these tests from the "randomization tests" based on the physical act of randomization. The practical importance of this distinction is illustrated…

利用广义加性模型与深度神经网络估计高分辨率用电峰值AI 解读

This paper covers predicting high-resolution electricity peak demand features given lower-resolution data. This is a relevant setup as it answers whether limited higher-resolution monitoring helps to estimate future high-resolution peak loads when the high-resolution data is no longer available. That question is particularly interesting for network operators considering replacing high-resolution monitoring predictive models due to economic considerations. We propose models…

利用贝叶斯上下文树检测离散数据变点并进行分段AI 解读

A new Bayesian modelling framework is introduced for piece-wise homogeneous variable-memory Markov chains, along with a collection of effective algorithmic tools for change-point detection and segmentation of discrete time series. Building on the recently introduced Bayesian Context Trees (BCT) framework, the distributions of different segments in a discrete time series are described as variable-memory Markov chains. Inference for the presence and location of change-points…

泛函与理想点预测的可测性AI 解读

The ideal probabilistic forecast for a random variable $Y$ based on an information set $\mathcal{F}$ is the conditional distribution of $Y$ given $\mathcal{F}$. In the context of point forecasts aiming to specify a functional $T$ such as the mean, a quantile or a risk measure, the ideal point forecast is the respective functional applied to the conditional distribution. This paper provides a theoretical justification why this ideal forecast is actually a forecast, that is,…

医疗服务量与结局关系的建模AI 解读

Despite the ongoing strong interest in associations between quality of care and the volume of health care providers, a unified statistical framework for analyzing them is missing, and many studies suffer from poor statistical modelling choices. We propose a flexible, additive mixed model for studying volume-outcome associations in health care that takes into account individual patient characteristics as well as provider-specific effects through a multi-level approach. More…

面向数据科学家的预测评估：常见陷阱与最佳实践AI 解读

Machine Learning (ML) and Deep Learning (DL) methods are increasingly replacing traditional methods in many domains involved with important decision making activities. DL techniques tailor-made for specific tasks such as image recognition, signal processing, or speech analysis are being introduced at a fast pace with many improvements. However, for the domain of forecasting, the current state in the ML community is perhaps where other domains such as Natural Language…

分组固定效应模型的简便低计算成本估计量AI 解读

This paper introduces a new fixed effects estimator for linear panel data models with clustered time patterns of unobserved heterogeneity. The method avoids non-convex and combinatorial optimization by combining a preliminary consistent estimator of the slope coefficient, an agglomerative pairwise-differencing clustering of cross-sectional units, and a pooled ordinary least squares regression. Asymptotic guarantees are established in a framework where $T$ can grow at any…

协变量漂移下预测集的双重稳健校准AI 解读

Conformal prediction has received tremendous attention in recent years and has offered new solutions to problems in missing data and causal inference; yet these advances have not leveraged modern semiparametric efficiency theory for more robust and efficient uncertainty quantification. In this paper, we consider the problem of obtaining distribution-free prediction regions accounting for a shift in the distribution of the covariates between the training and test data. Under…

暴露测量误差导致的多变量孟德尔随机化偏倚AI 解读

Multivariable Mendelian randomization estimates the causal effect of multiple exposures on an outcome, typically using summary statistics of genetic variant associations. However, exposures of interest in Mendelian randomization applications will often be measured with error. The summary statistics will therefore not be of the genetic associations with the exposure, but with the exposure measured with error. Classical measurement error will not bias genetic association…

非参数条件局部独立性检验AI 解读

Conditional local independence is an asymmetric independence relation among continuous time stochastic processes. It describes whether the evolution of one process is directly influenced by another process given the histories of additional processes, and it is important for the description and learning of causal relations among processes. We develop a model-free framework for testing the hypothesis that a counting process is conditionally locally independent of another…

异质性因果效应估计的极小极大收敛速率AI 解读

Estimation of heterogeneous causal effects - i.e., how effects of policies and treatments vary across subjects - is a fundamental task in causal inference. Many methods for estimating conditional average treatment effects (CATEs) have been proposed in recent years, but questions surrounding optimality have remained largely unanswered. In particular, a minimax theory of optimality has yet to be developed, with the minimax rate of convergence and construction of rate-optimal…

高维矩阵椭圆因子模型的流形主成分分析AI 解读

Matrix factor model has been growing popular in scientific fields such as econometrics, which serves as a two-way dimension reduction tool for matrix sequences. In this article, we for the first time propose the matrix elliptical factor model, which can better depict the possible heavy-tailed property of matrix-valued data especially in finance. Manifold Principle Component Analysis (MPCA) is for the first time introduced to estimate the row/column loading spaces. MPCA first…

用高维渐近理论解释处理效应估计器的实际差异AI 解读

We revisit the classical causal inference problem of estimating the average treatment effect in the presence of fully observed confounding variables using two-stage semiparametric methods. In existing theoretical studies of methods such as G-computation, inverse propensity weighting (IPW), and two common doubly robust estimators -- augmented IPW (AIPW) and targeted maximum likelihood estimation (TMLE) -- they are either bias-dominated, or have similar asymptotic statistical…

合成控制法的预测变量选择AI 解读

Synthetic control methods often rely on matching pre-treatment characteristics (called predictors) of the treated unit. The choice of predictors and how they are weighted plays a key role in the performance and interpretability of synthetic control estimators. This paper proposes the use of a sparse synthetic control procedure that penalizes the number of predictors used in generating the counterfactual to select the most important predictors. We derive, in a linear factor…

具有共同响应与预测因子的高维向量自回归AI 解读

The reduced-rank vector autoregressive (VAR) model can be interpreted as a supervised factor model, where two factor modelings are simultaneously applied to response and predictor spaces. This article introduces a new model, called vector autoregression with common response and predictor factors, to explore further the common structure between the response and predictors in the VAR framework. The new model can provide better physical interpretations and improve estimation…

因果 de Finetti：可交换数据中不变因果结构的识别AI 解读

Constraint-based causal discovery methods leverage conditional independence tests to infer causal relationships in a wide variety of applications. Just as the majority of machine learning methods, existing work focuses on studying $\textit{independent and identically distributed}$ data. However, it is known that even with infinite i.i.d.$\ $ data, constraint-based methods can only identify causal structures up to broad Markov equivalence classes, posing a fundamental…

非可交换数据下的分割保形预测AI 解读

Split conformal prediction (CP) is arguably the most popular CP method for uncertainty quantification, enjoying both academic interest and widespread deployment. However, the original theoretical analysis of split CP makes the crucial assumption of data exchangeability, which hinders many real-world applications. In this paper, we present a novel theoretical framework based on concentration inequalities and decoupling properties of the data, proving that split CP remains…