每日简报

删失事件时间数据中的反事实表型识别AI 解读

Estimation of treatment efficacy of real-world clinical interventions involves working with continuous outcomes such as time-to-death, re-hospitalization, or a composite event that may be subject to censoring. Counterfactual reasoning in such scenarios requires decoupling the effects of confounding physiological characteristics that affect baseline survival rates from the effects of the interventions being assessed. In this paper, we present a latent variable approach to…

作为在线线性回归的合成控制AI 解读

This paper notes a simple connection between synthetic control and online learning. Specifically, we recognize synthetic control as an instance of Follow-The-Leader (FTL). Standard results in online convex optimization then imply that, even when outcomes are chosen by an adversary, synthetic control predictions of counterfactual outcomes for the treated unit perform almost as well as an oracle weighted average of control units' outcomes. Synthetic control on differenced data…

重复事件与竞争事件下的因果推断AI 解读

Many research questions concern treatment effects on outcomes that can recur several times in the same individual. For example, medical researchers are interested in treatment effects on hospitalizations in heart failure patients and sports injuries in athletes. Competing events, such as death, complicate causal inference in studies of recurrent events because once a competing event occurs, an individual cannot have more recurrent events. Several statistical estimands have…

含时变协变量的双重差分AI 解读

This paper considers identification and estimation of causal effect parameters from participating in a binary treatment in a difference in differences (DID) setup when the parallel trends assumption holds after conditioning on observed covariates. Relative to existing work in the econometrics literature, we consider the case where the value of covariates can change over time and, potentially, where participating in the treatment can affect the covariates themselves. We…

非线性网络自回归AI 解读

We study general nonlinear models for time series networks of integer and continuous valued data. The vector of high dimensional responses, measured on the nodes of a known network, is regressed non-linearly on its lagged value and on lagged values of the neighboring nodes by employing a smooth link function. We study stability conditions for such multivariate process and develop quasi maximum likelihood inference when the network dimension is increasing. In addition, we…

基于优化的因果效应估计方法：综述与实证比较AI 解读

In the absence of randomized controlled and natural experiments, it is necessary to balance the distributions of (observable) covariates of the treated and control groups in order to obtain an unbiased estimate of a causal effect of interest; otherwise, a different effect size may be estimated, and incorrect recommendations may be given. To achieve this balance, there exist a wide variety of methods. In particular, several methods based on optimization models have been…

因果推断方法的验证：Credence 生成式框架AI 解读

The fundamental challenge of drawing causal inference is that counterfactual outcomes are not fully observed for any unit. Furthermore, in observational studies, treatment assignment is likely to be confounded. Many statistical methods have emerged for causal inference under unconfoundedness conditions given pre-treatment covariates, including propensity score-based methods, prognostic score-based methods, and doubly robust methods. Unfortunately for applied researchers,…

持续混杂下通过数据结合开展长期因果推断AI 解读

We study the identification and estimation of long-term treatment effects when both experimental and observational data are available. Since the long-term outcome is observed only after a long delay, it is not measured in the experimental data, but only recorded in the observational data. However, both types of data include observations of some short-term outcomes. In this paper, we uniquely tackle the challenge of persistent unmeasured confounders, i.e., some unmeasured…

实验结果推广中的敏感性分析AI 解读

Randomized controlled trials (RCT's) allow researchers to estimate causal effects in an experimental sample with minimal identifying assumptions. However, to generalize or transport a causal effect from an RCT to a target population, researchers must adjust for a set of treatment effect moderators. In practice, it is impossible to know whether the set of moderators has been properly accounted for. In the following paper, I propose a three parameter sensitivity analysis for…

利用可处理电路进行因果推断AI 解读

The aim of this paper is to discuss a recent result which shows that probabilistic inference in the presence of (unknown) causal mechanisms can be tractable for models that have traditionally been viewed as intractable. This result was reported recently to facilitate model-based supervised learning but it can be interpreted in a causality context as follows. One can compile a non-parametric causal graph into an arithmetic circuit that supports inference in time linear in the…

利用独立工具变量实现识别与分布泛化AI 解读

Instrumental variable models allow us to identify a causal function between covariates $X$ and a response $Y$, even in the presence of unobserved confounding. Most of the existing estimators assume that the error term in the response $Y$ and the hidden confounders are uncorrelated with the instruments $Z$. This is often motivated by a graphical separation, an argument that also justifies independence. Positing an independence restriction, however, leads to strictly stronger…

异质性因果效应的差分隐私估计AI 解读

Estimating heterogeneous treatment effects in domains such as healthcare or social science often involves sensitive data where protecting privacy is important. We introduce a general meta-algorithm for estimating conditional average treatment effects (CATE) with differential privacy (DP) guarantees. Our meta-algorithm can work with simple, single-stage CATE estimators such as S-learner and more complex multi-stage estimators such as DR and R-learner. We perform a tight…

受新冠疫情影响的临床试验：目标估计量及其估计方法AI 解读

The COVID-19 pandemic continues to affect the conduct of clinical trials globally. Complications may arise from pandemic-related operational challenges such as site closures, travel limitations and interruptions to the supply chain for the investigational product, or from health-related challenges such as COVID-19 infections. Some of these complications lead to unforeseen intercurrent events in the sense that they affect either the interpretation or the existence of the…

线性回归预测条件平均处理效应中的良性过拟合AI 解读

We study the benign overfitting theory in the prediction of the conditional average treatment effect (CATE), with linear regression models. As the development of machine learning for causal inference, a wide range of large-scale models for causality are gaining attention. One problem is that suspicions have been raised that the large-scale models are prone to overfitting to observations with sample selection, hence the large models may not be suitable for causal prediction.…

利用因果图归一化流分析 IMF 项目对全球南方儿童贫困的影响AI 解读

This work demonstrates the application of a particular branch of causal inference and deep learning models: \emph{causal-Graphical Normalizing Flows (c-GNFs)}. In a recent contribution, scholars showed that normalizing flows carry certain properties, making them particularly suitable for causal and counterfactual analysis. However, c-GNFs have only been tested in a simulated data setting and no contribution to date have evaluated the application of c-GNFs on large-scale…

在相对效应可迁移假设下识别新目标人群的处理效应AI 解读

Epidemiologists and applied statisticians often believe that relative effect measures conditional on covariates, such as risk ratios and mean ratios, are ``transportable'' across populations. Here, we examine the identification of causal effects in a target population using an assumption that conditional relative effect measures (e.g., conditional risk ratios or mean ratios) are transportable from a trial to the target population. We show that transportability for relative…

动态二元选择面板数据模型的半参数估计AI 解读

We propose a new approach to the semiparametric analysis of panel data binary choice models with fixed effects and dynamics (lagged dependent variables). The model we consider has the same random utility framework as in Honore and Kyriazidou (2000). We demonstrate that, with additional serial dependence conditions on the process of deterministic utility and tail restrictions on the error distribution, the (point) identification of the model can proceed in two steps, and only…

动态离散选择模型中的连续永久不可观测异质性AI 解读

In dynamic discrete choice (DDC) analysis, it is common to use mixture models to control for unobserved heterogeneity. However, consistent estimation typically requires both restrictions on the support of unobserved heterogeneity and a high-level injectivity condition that is difficult to verify. This paper provides primitive conditions for point identification of a broad class of DDC models with multivariate continuous permanent unobserved heterogeneity. The results apply…

结构计量中的公平性约束及其工具变量估计应用AI 解读

A supervised machine learning algorithm determines a model from a learning sample that will be used to predict new observations. To this end, it aggregates individual characteristics of the observations of the learning sample. But this information aggregation does not consider any potential selection on unobservables and any status-quo biases which may be contained in the training sample. The latter bias has raised concerns around the so-called \textit{fairness} of machine…

有序结果与二元中介变量的精确中介分析AI 解读

With reference to a single mediator context, this brief report presents a model-based strategy to estimate counterfactual direct and indirect effects when the response variable is ordinal and the mediator is binary. Postulating a logistic regression model for the mediator and a cumulative logit model for the outcome, the exact parametric formulation of the causal effects is presented, thereby extending previous work that only contained approximated results. The…

连续时间生存与事件史分析中边际因果效应识别的图准则AI 解读

We consider continuous-time survival or more general event-history settings, where the aim is to infer the causal effect of a time-dependent treatment process. This is formalised as the effect on the outcome event of a (possibly hypothetical) intervention on the intensity of the treatment process, i.e. a stochastic intervention. To establish whether valid inference about the interventional situation can be drawn from typical observational, i.e. non-experimental, data we…

scpi：合成控制方法的不确定性量化AI 解读

The synthetic control method offers a way to quantify the effect of an intervention using weighted averages of untreated units to approximate the counterfactual outcome that the treated unit(s) would have experienced in the absence of the intervention. This method is useful for program evaluation and causal inference in observational studies. We introduce the software package scpi for prediction and inference using synthetic controls, implemented in Python, R, and Stata. For…

利用纵向修正治疗策略开展竞争风险下的因果生存分析AI 解读

Longitudinal modified treatment policies (LMTP) have been recently developed as a novel method to define and estimate causal parameters that depend on the natural value of treatment. LMTPs represent an important advancement in causal inference for longitudinal studies as they allow the non-parametric definition and estimation of the joint effect of multiple categorical, numerical, or continuous exposures measured at several time points. We extend the LMTP methodology to…

In this paper, we develop a novel high-dimensional time-varying coefficient estimation method, based on high-dimensional Itô diffusion processes. To account for high-dimensional time-varying coefficients, we first estimate local (or instantaneous) coefficients using a time-localized Dantzig selection scheme under a sparsity condition, which results in biased local coefficient estimators due to the regularization. To handle the bias, we propose a debiasing scheme, which…