每日简报

以贝叶斯证据综合纳入真实世界证据评估替代终点AI 解读

Objective: Traditionally validation of surrogate endpoints has been carried out using RCT data. However, RCT data may be too limited to validate surrogate endpoints. In this paper, we sought to improve validation of surrogate endpoints with the inclusion of real world evidence (RWE). Study Design and Setting: We use data from comparative RWE (cRWE) and single arm RWE (sRWE), to supplement RCT evidence for evaluation of progression free survival (PFS) as a surrogate endpoint…

工具变量下的因果中介分析AI 解读

Mediation analysis is a strategy for understanding the mechanisms by which treatments or interventions affect later outcomes. Mediation analysis is frequently applied in randomized trial settings, but typically assumes: a) that randomized assignment is the exposure of interest as opposed to actual take-up of the intervention, and b) no unobserved confounding of the mediator-outcome relationship. In contrast to the rich literature on instrumental variable (IV) methods to…

时间序列的最优差分型方差估计：一般框架AI 解读

Variance estimation is important for statistical inference. It becomes non-trivial when observations are masked by serial dependence structures and time-varying mean structures. Existing methods either ignore or sub-optimally handle these nuisance structures. This paper develops a general framework for the estimation of the long-run variance for time series with non-constant means. The building blocks are difference statistics. The proposed class of estimators is general…

门限框架下自助法检验的有效性AI 解读

We consider bootstrap-based testing for threshold effects in non-linear threshold autoregressive (TAR) models. It is well-known that classic tests based on asymptotic theory tend to be oversized in the case of small, or even moderate sample sizes, or when the estimated parameters indicate non-stationarity, as often witnessed in the analysis of financial or climate data. To address the issue we propose a supremum Lagrange Multiplier test statistic (sLMb), where the null…

通过自归一化分割时间序列AI 解读

We propose a novel and unified framework for change-point estimation in multivariate time series. The proposed method is fully nonparametric, enjoys effortless tuning and is robust to temporal dependence. One salient and distinct feature of the proposed method is its versatility, where it allows change-point detection for a broad class of parameters (such as mean, variance, correlation and quantile) in a unified fashion. At the core of our method, we couple the…

具有溢出效应的连续处理模型估计：控制函数方法AI 解读

We study a continuous treatment effect model in the presence of treatment spillovers through social networks. We assume that one's outcome is affected not only by his/her own treatment but also by a (weighted) average of his/her neighbors' treatments, both of which are treated as endogenous variables. Using a control function approach with appropriate instrumental variables, we show that the conditional mean potential outcome can be nonparametrically identified. We also…

回归不连续设计中的视觉推断与图形呈现AI 解读

Despite the widespread use of graphs in empirical research, little is known about readers' ability to process the statistical information they are meant to convey ("visual inference"). We study visual inference within the context of regression discontinuity (RD) designs by measuring how accurately readers identify discontinuities in graphs produced from data generating processes calibrated on 11 published papers from leading economics journals. First, we assess the effects…

用于构建临床试验合成对照组的贝叶斯非参数共同原子回归AI 解读

The availability of electronic health records (EHR) has opened opportunities to supplement increasingly expensive and difficult to carry out randomized controlled trials (RCT) with evidence from readily available real world data. In this paper, we use EHR data to construct synthetic control arms for treatment-only single arm trials. We propose a novel nonparametric Bayesian common atoms mixture model that allows us to find equivalent population strata in the EHR and the…

没有显著星号是好消息：基于协变量平衡检验 p 值的再随机化AI 解读

Modern social and biomedical scientific publications require the reporting of covariate balance tables with not only covariate means by treatment group but also the associated $p$-values from significance tests of their differences. The practical need to avoid small $p$-values renders balance check and rerandomization by hypothesis testing standards an attractive tool for improving covariate balance in randomized experiments. Despite the intuitiveness of such practice and…

条件分布局部线性回归估计的一致收敛结果AI 解读

This paper examines the local linear regression (LLR) estimate of the conditional distribution function $F(y|x)$. We derive three uniform convergence results: the uniform bias expansion, the uniform convergence rate, and the uniform asymptotic linear representation. The uniformity in the above results is with respect to both $x$ and $y$ and therefore has not previously been addressed in the literature on local polynomial regression. Such uniform convergence results are…

SCR：利用一致性正则化训练图神经网络AI 解读

We present the SCR framework for enhancing the training of graph neural networks (GNNs) with consistency regularization. Regularization is a set of strategies used in Machine Learning to reduce overfitting and improve the generalization ability. However, it is unclear how to best design the generalization strategies in GNNs, as it works in a semi-supervised setting for graph data. The major challenge lies in how to efficiently balance the trade-off between the error from the…

时间序列数据的高维 Knockoffs 推断AI 解读

We make some initial attempt to establish the theoretical and methodological foundation for the model-X knockoffs inference for time series data. We suggest the method of time series knockoffs inference (TSKI) by exploiting the ideas of subsampling and e-values to address the difficulty caused by the serial dependence. We also generalize the robust knockoffs inference in Barber, Candès, and Samworth to the time series setting to relax the assumption of known covariate…

协变量分布偏移下外部有效性的简明稳健性度量AI 解读

This paper studies the robustness of estimated policy effects to changes in the distribution of covariates, a key determinant of the external validity of (quasi)-experimental results. I propose a novel robustness metric $δ^*$ which measures the smallest covariate shift needed to invalidate an empirical claim about the policy effect (e.g., $ATE > 0$). I estimate $δ^*$ via de-biased GMM, achieving a parametric rate of convergence while accommodating machine-learning estimators…

从随机时间扭曲观测中估计时间序列AI 解读

We consider the problem of estimating a signal from its warped observations. Such estimation is commonly performed by altering the observations through some inverse-warping, or solving a computationally demanding optimization formulation. While these may be unavoidable if observations are few, when large amounts of warped observations are available, the cost of running such algorithms can be prohibitive. We consider the scenario where we have many observations, and propose a…

深度分位数回归与深度拼接模型回归AI 解读

A main difficulty in actuarial claim size modeling is that there is no simple off-the-shelf distribution that simultaneously provides a good distributional model for the main body and the tail of the data. In particular, covariates may have different effects for small and for large claim sizes. To cope with this problem, we introduce a deep composite regression model whose splicing point is given in terms of a quantile of the conditional claim size distribution rather than a…

含外生协变量的离散值时间序列的强混合性质AI 解读

We derive strong mixing conditions for many existing discrete-valued time series models that include exogenous covariates in the dynamic. Our main contribution is to study how a mixing condition on the covariate process transfers to a mixing condition for the response. Using a coupling method, we first derive mixing conditions for some Markov chains in random environments, which gives a first result for some autoregressive categorical processes with strictly exogenous…

时间序列 SIR 模型放宽均匀混合假设的统计后果AI 解读

Infectious disease epidemiologists routinely fit stochastic epidemic models to time series data to elucidate infectious disease dynamics, evaluate interventions, and forecast epidemic trajectories. To improve computational tractability, many approximate stochastic models have been proposed. In this paper, we focus on one class of such approximations -- time series Susceptible-Infectious-Removed (TSIR) models. Infectious disease modeling often starts with a homogeneous mixing…

利用高斯过程进行期权定价的贝叶斯方法AI 解读

Local volatility is a versatile option pricing model due to its state dependent diffusion coefficient. Calibration is, however, non-trivial as it involves both proposing a hypothesis model of the latent function and a method for fitting it to data. In this paper we present novel Bayesian inference with Gaussian process priors. We obtain a rich representation of the local volatility function with a probabilistic notion of uncertainty attached to the calibrate. We propose an…

评估“进步悖论”的分解方法：阿根廷证据AI 解读

The `paradox of progress' is an empirical regularity that associates more education with larger income inequality. Two driving and competing factors behind this phenomenon are the convexity of the `Mincer equation' (that links wages and education) and the heterogeneity in its returns, as captured by quantile regressions. We propose a joint least-squares and quantile regression statistical framework to derive a decomposition in order to evaluate the relative contribution of…

利用偏相干统计量检验因果影响AI 解读

In this paper we explore partial coherence as a tool for evaluating causal influence of one signal sequence on another. In some cases the signal sequence is sampled from a time- or space-series. The key idea is to establish a connection between questions of causality and questions of partial coherence. Once this connection is established, then a scale-invariant partial coherence statistic is used to resolve the question of causality. This coherence statistic is shown to be a…

反事实情景中因果人群分布的非参数估计AI 解读

In causality, estimating the effect of a treatment without confounding inference remains a major issue because requires to assess the outcome in both case with and without treatment. Not being able to observe simultaneously both of them, the estimation of potential outcome remains a challenging task. We propose an innovative approach where the problem is reformulated as a missing data model. The aim is to estimate the hidden distribution of \emph{causal populations}, defined…

半参数离散选择模型的高效反事实估计：一则方法补充AI 解读

I suggest an enhancement of the procedure of Chiong, Hsieh, and Shum (2017) for calculating bounds on counterfactual demand in semiparametric discrete choice models. Their algorithm relies on a system of inequalities indexed by cycles of a large number $M$ of observed markets and hence seems to require computationally infeasible enumeration of all such cycles. I show that such enumeration is unnecessary because solving the "fully efficient" inequality system exploiting…

基于洛伦兹曲线与集中曲线的房价预测模型选择：德黑兰证据AI 解读

This study contributes a house price prediction model selection in Tehran City based on the area between Lorenz curve (LC) and concentration curve (CC) of the predicted price by using 206,556 observed transaction data over the period from March 21, 2018, to February 19, 2021. Several different methods such as generalized linear models (GLM) and recursive partitioning and regression trees (RPART), random forests (RF) regression models, and neural network (NN) models were…

R 包 knnwtsim：使用定制相似度的非参数预测AI 解读

The R package knnwtsim provides functions to implement k nearest neighbors (KNN) forecasting using a similarity metric tailored to the forecasting problem of predicting future observations of a response series where recent observations, seasonal or periodic patterns, and the values of one or more exogenous predictors all have predictive value in forecasting new response points. This paper will introduce the similarity measure of interest, and the functions in knnwtsim used…