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处理效应随暴露时间变化时的阶梯楔形整群随机试验分析AI 解读

Stepped wedge cluster randomized controlled trials are typically analyzed using models that assume the full effect of the treatment is achieved instantaneously. We provide an analytical framework for scenarios in which the treatment effect varies as a function of exposure time (time since the start of treatment) and define the "effect curve" as the magnitude of the treatment effect on the linear predictor scale as a function of exposure time. The "time-averaged treatment…

线性模型中可扩展的干预目标估计AI 解读

This paper considers the problem of estimating the unknown intervention targets in a causal directed acyclic graph from observational and interventional data. The focus is on soft interventions in linear structural equation models (SEMs). Current approaches to causal structure learning either work with known intervention targets or use hypothesis testing to discover the unknown intervention targets even for linear SEMs. This severely limits their scalability and sample…

动态网络分位数回归模型AI 解读

We propose a dynamic network quantile regression model to investigate the quantile connectedness using a predetermined network information. We extend the existing network quantile autoregression model of Zhu et al. (2019b) by explicitly allowing the contemporaneous network effects and controlling for the common factors across quantiles. To cope with the endogeneity issue due to simultaneous network spillovers, we adopt the instrumental variable quantile regression (IVQR)…

将伴发事件下的随机临床试验问题转化为目标估计量AI 解读

Intercurrent (post-treatment) events occur frequently in randomized trials, and investigators often express interest in treatment effects that suitably take account of these events. A naive conditioning on intercurrent events does not have a straight-forward causal interpretation, and the practical relevance of other commonly used approaches is debated. In this work, we discuss how to formulate and choose an estimand, beyond the marginal intention to treat effect, from the…

通过匹配随机特征进行模拟推断：一则札记AI 解读

We can, and should, do statistical inference on simulation models by adjusting the parameters in the simulation so that the values of {\em randomly chosen} functions of the simulation output match the values of those same functions calculated on the data. Results from the "state-space reconstruction" or "geometry from a time series'' literature in nonlinear dynamics indicate that just $2d+1$ such functions will typically suffice to identify a model with a $d$-dimensional…

利用连续工具变量对非随机缺失数据进行非参数扫描AI 解读

This article introduces a new instrumental variable approach for estimating unknown population parameters with data having nonrandom missing values. With coarse and discrete instruments, Shao and Wang (2016) proposed a semiparametric method that uses the added information to identify the tilting parameter from the missing data propensity model. A naive application of this idea to continuous instruments through arbitrary discretizations is apt to be inefficient, and maybe…

影响下的随机对照试验：协变量因素与图网络干扰AI 解读

Randomized controlled trials are not only the golden standard in medicine and vaccine trials but have spread to many other disciplines like behavioral economics, making it an important interdisciplinary tool for scientists. When designing randomized controlled trials, how to assign participants to treatments becomes a key issue. In particular in the presence of covariate factors, the assignment can significantly influence statistical properties and thereby the quality of the…

中美贸易战对股票市场的影响：金融传染视角AI 解读

In this paper, we investigate the effect of the U.S.--China trade war on stock markets from a financial contagion perspective, based on high-frequency financial data. Specifically, to account for risk contagion between the U.S. and China stock markets, we develop a novel jump-diffusion process. For example, we consider three channels for volatility contagion--such as integrated volatility, positive jump variation, and negative jump variation--and each stock market is able to…

多协变量调整随机化下最优个体化治疗策略的灵活推断AI 解读

To maximize clinical benefit, clinicians routinely tailor treatment to the individual characteristics of each patient, where individualized treatment rules are needed and are of significant research interest to statisticians. In the covariate-adjusted randomization clinical trial with many covariates, we model the treatment effect with an unspecified function of a single index of the covariates and leave the baseline response completely arbitrary. We devise a class of…

回归折点设计中的优化推断AI 解读

We propose a method to remedy finite sample coverage problems and improve upon the efficiency of commonly employed procedures for the construction of nonparametric confidence intervals in regression kink designs. The proposed interval is centered at the half-length optimal, numerically obtained linear minimax estimator over distributions with Lipschitz constrained conditional mean function. Its construction ensures excellent finite sample coverage and length properties which…

季节性计数时间序列AI 解读

Count time series are widely encountered in practice. As with continuous valued data, many count series have seasonal properties. This paper uses a recent advance in stationary count time series to develop a general seasonal count time series modeling paradigm. The model permits any marginal distribution for the series and the most flexible autocorrelations possible, including those with negative dependence. Likelihood methods of inference can be conducted and covariates can…

合成控制为何有偏及其修正：放松与惩罚合成控制AI 解读

This paper extends the literature on the theoretical properties of synthetic controls to the case of non-linear generative models, showing that the synthetic control estimator is generally biased in such settings. I derive a lower bound for the bias, showing that the only component of it that is affected by the choice of synthetic control is the weighted sum of pairwise differences between the treated unit and the untreated units in the synthetic control. To address this…

通过虚拟 VAR 建模解析因果关系AI 解读

In modeling multivariate time series for either forecast or policy analysis, it would be beneficial to have figured out the cause-effect relations within the data. Regression analysis, however, is generally for correlation relation, and very few researches have focused on variance analysis for causality discovery. We first set up an equilibrium for the cause-effect relations using a fictitious vector autoregressive model. In the equilibrium, long-run relations are identified…

天气预报精度的空间相关：函数型时间序列方法AI 解读

A functional time series approach is proposed for investigating spatial correlation in daily maximum temperature forecast errors for 111 cities spread across the U.S. The modelling of spatial correlation is most fruitful for longer forecast horizons, and becomes less relevant as the forecast horizon shrinks towards zero. For 6-day-ahead forecasts, the functional approach uncovers interpretable regional spatial effects, and captures the higher variance observed in inland…

高维高斯时间序列频率平滑谱相干矩阵的线性谱统计性质AI 解读

The asymptotic behaviour of Linear Spectral Statistics (LSS) of the smoothed periodogram estimator of the spectral coherency matrix of a complex Gaussian high-dimensional time series $(\y_n)_{n \in \mathbb{Z}}$ with independent components is studied under the asymptotic regime where the sample size $N$ converges towards $+\infty$ while the dimension $M$ of $\y$ and the smoothing span of the estimator grow to infinity at the same rate in such a way that $\frac{M}{N} \rightarrow 0$…

差异化产品需求系统的最大似然估计AI 解读

We discuss estimation of the differentiated products demand system of Berry et al (1995) (BLP) by maximum likelihood estimation (MLE). We derive the maximum likelihood estimator in the case where prices are endogenously generated by firms that set prices in Bertrand-Nash equilibrium. In Monte Carlo simulations the MLE estimator outperforms the best-practice GMM estimator on both bias and mean squared error when the model is correctly specified. This remains true under some…

在线因果推断及其在近实时疫苗上市后安全监测中的应用AI 解读

Streaming data routinely generated by mobile phones, social networks, e-commerce, and electronic health records present new opportunities for near real-time surveillance of the impact of an intervention on an outcome of interest via causal inference methods. However, as data grow rapidly in volume and velocity, storing and combing data become increasingly challenging. The amount of time and effort spent to update analyses can grow exponentially, which defeats the purpose of…

低维与高维 Beta 回归的岭型收缩估计及其应用AI 解读

Beta regression model is useful in the analysis of bounded continuous outcomes such as proportions. It is well known that for any regression model, the presence of multicollinearity leads to poor performance of the maximum likelihood estimators. The ridge type estimators have been proposed to alleviate the adverse effects of the multicollinearity. Furthermore, when some of the predictors have insignificant or weak effects on the outcomes, it is desired to recover as much…

带 Gamma 超先验的逆问题：一种变分推断方法AI 解读

Hierarchical models with gamma hyperpriors provide a flexible, sparse-promoting framework to bridge $L^1$ and $L^2$ regularizations in Bayesian formulations to inverse problems. Despite the Bayesian motivation for these models, existing methodologies are limited to \textit{maximum a posteriori} estimation. The potential to perform uncertainty quantification has not yet been realized. This paper introduces a variational iterative alternating scheme for hierarchical inverse…

时序文本数据中主题比例的变点分析AI 解读

Changepoint analysis deals with unsupervised detection and/or estimation of time-points in time-series data, when the distribution generating the data changes. In this article, we consider \emph{offline} changepoint detection in the context of large scale textual data. We build a specialised temporal topic model with provisions for changepoints in the distribution of topic proportions. As full likelihood based inference in this model is computationally intractable, we…

变量选择后危险比推断的有效性AI 解读

The problem of how to best select variables for confounding adjustment forms one of the key challenges in the evaluation of exposure effects in observational studies, and has been the subject of vigorous recent activity in causal inference. A major drawback of routine procedures is that there is no finite sample size at which they are guaranteed to deliver exposure effect estimators and associated confidence intervals with adequate performance. In this work, we will consider…

贝叶斯非参数因果推断：方法与理由AI 解读

Spurred on by recent successes in causal inference competitions, Bayesian nonparametric (and high-dimensional) methods have recently seen increased attention in the causal inference literature. In this paper, we present a comprehensive overview of Bayesian nonparametric applications to causal inference. Our aims are to (i) introduce the fundamental Bayesian nonparametric toolkit; (ii) discuss how to determine which tool is most appropriate for a given problem; and (iii) show…

利用分位点局部多项式决策树与森林建模异质性处理效应AI 解读

To further develop the statistical inference problem for heterogeneous treatment effects, this paper builds on Breiman's (2001) random forest tree (RFT)and Wager et al.'s (2018) causal tree to parameterize the nonparametric problem using the excellent statistical properties of classical OLS and the division of local linear intervals based on covariate quantile points, while preserving the random forest trees with the advantages of constructible confidence intervals and…

用于向量自回归的灵活贝叶斯乘积混合模型AI 解读

Bayesian non-parametric methods based on Dirichlet process mixtures have seen tremendous success in various domains and are appealing in being able to borrow information by clustering samples that share identical parameters. However, such methods can face hurdles in heterogeneous settings where objects are expected to cluster only along a subset of axes or where clusters of samples share only a subset of identical parameters. We overcome such limitations by developing a…