每日简报

连续处理下的双重差分AI 解读

This paper analyzes difference-in-differences designs with a continuous treatment. We show that treatment-on-the-treated-type parameters are identified under a parallel trends assumption analogous to the binary treatment case. However, comparing these parameters across treatments is challenging because parallel trends does not rule out selection bias. We discuss alternative, typically stronger, assumptions that eliminate selection bias. We further show that popular two-way…

理解基于有效影响函数的统计学习AI 解读

Evaluation of treatment effects and more general estimands is typically achieved via parametric modelling, which is unsatisfactory since model misspecification is likely. Data-adaptive model building (e.g. statistical/machine learning) is commonly employed to reduce the risk of misspecification. Naive use of such methods, however, delivers estimators whose bias may shrink too slowly with sample size for inferential methods to perform well, including those based on the…

时间序列截面数据因果推断的反事实估计实用指南AI 解读

This paper introduces a simple framework of counterfactual estimation for causal inference with time-series cross-sectional data, in which we estimate the average treatment effect on the treated by directly imputing counterfactual outcomes for treated observations. We discuss several novel estimators under this framework, including the fixed effects counterfactual estimator, interactive fixed effects counterfactual estimator, and matrix completion estimator. They provide…

连续处理因果推断的独立性权重AI 解读

Studying causal effects of continuous treatments is important for gaining a deeper understanding of many interventions, policies, or medications, yet researchers are often left with observational studies for doing so. In the observational setting, confounding is a barrier to the estimation of causal effects. Weighting approaches seek to control for confounding by reweighting samples so that confounders are comparable across different treatment values. Yet, for continuous…

评估缓解新冠疫情的公共卫生干预策略AI 解读

Coronavirus disease 2019 (COVID-19) pandemic is an unprecedented global public health challenge. In the United States (US), state governments have implemented various non-pharmaceutical interventions (NPIs), such as physical distance closure (lockdown), stay-at-home order, mandatory facial mask in public in response to the rapid spread of COVID-19. To evaluate the effectiveness of these NPIs, we propose a nested case-control design with propensity score weighting under the…

利用任意替代实验识别嵌套反事实AI 解读

The Ladder of Causation describes three qualitatively different types of activities an agent may be interested in engaging in, namely, seeing (observational), doing (interventional), and imagining (counterfactual) (Pearl and Mackenzie, 2018). The inferential challenge imposed by the causal hierarchy is that data is collected by an agent observing or intervening in a system (layers 1 and 2), while its goal may be to understand what would have happened had it taken a different…

固定效应动态离散选择模型中平均边际效应的识别AI 解读

In nonlinear panel data models, fixed effects methods are often criticized because they cannot identify average marginal effects (AMEs) in short panels. The common argument is that identifying AMEs requires knowledge of the distribution of unobserved heterogeneity, but this distribution is not identified in a fixed effects model with a short panel. In this paper, we derive identification results that contradict this argument. In a panel data dynamic logit model, and for $T$ a…

异质性部分干扰下观测研究处理效应的半参数估计AI 解读

In many observational studies in social science and medicine, subjects or units are connected, and one unit's treatment and attributes may affect another's treatment and outcome, violating the stable unit treatment value assumption (SUTVA) and resulting in interference. To enable feasible estimation and inference, many previous works assume exchangeability of interfering units (neighbors). However, in many applications with distinctive units, interference is heterogeneous…

非参数结构函数与弹性的自适应估计及一致置信带AI 解读

We introduce two data-driven procedures for optimal estimation and inference in nonparametric models using instrumental variables. The first is a data-driven choice of sieve dimension for a popular class of sieve two-stage least squares estimators. When implemented with this choice, estimators of both the structural function $h_0$ and its derivatives (such as elasticities) converge at the fastest possible (i.e., minimax) rates in sup-norm. The second is for constructing…

GENIUS-MAWII：应对大量弱且无效工具变量的稳健孟德尔随机化AI 解读

Mendelian randomization (MR) has become a popular approach to study causal effects by using genetic variants as instrumental variables. We propose a new MR method, GENIUS-MAWII, which simultaneously addresses the two salient phenomena that adversely affect MR analyses: many weak instruments and widespread horizontal pleiotropy. Similar to MR GENIUS (Tchetgen Tchetgen et al., 2021), we achieve identification of the treatment effect by leveraging heteroscedasticity of the…

低秩模型的统计推断AI 解读

This paper studies inference in linear models with a high-dimensional parameter matrix that can be well-approximated by a ``spiked low-rank matrix.'' A spiked low-rank matrix has rank that grows slowly compared to its dimensions and nonzero singular values that diverge to infinity. We show that this framework covers a broad class of models of latent-variables which can accommodate matrix completion problems, factor models, varying coefficient models, and heterogeneous…

面板数据中对处理分配设计稳健的双向固定效应回归AI 解读

We propose a new estimator for average causal effects of a binary treatment with panel data in settings with general treatment patterns. Our approach augments the popular two-way-fixed-effects specification with unit-specific weights that arise from a model for the assignment mechanism. We show how to construct these weights in various settings, including the staggered adoption setting, where units opt into the treatment sequentially but permanently. The resulting estimator…

通过局部图学习因果结构AI 解读

We consider the problem of learning causal structures in sparse high-dimensional settings that may be subject to the presence of (potentially many) unmeasured confounders, as well as selection bias. Based on the structure found in common families of large random networks and examining the representation of local structures in linear structural equation models (SEM), we propose a new local notion of sparsity for consistent structure learning in the presence of latent and…

调整还是不调整：协变量缺失的随机实验中平均处理效应估计AI 解读

Complete randomization allows for consistent estimation of the average treatment effect based on the difference in means of the outcomes without strong modeling assumptions on the outcome-generating process. Appropriate use of the pretreatment covariates can further improve the estimation efficiency. However, missingness in covariates is common in experiments and raises an important question: should we adjust for covariates subject to missingness, and if so, how? The…

贝叶斯分位数回归中收缩与变量选择的解耦AI 解读

This paper extends the idea of decoupling shrinkage and sparsity for continuous priors to Bayesian Quantile Regression (BQR). The procedure follows two steps: In the first step, we shrink the quantile regression posterior through state of the art continuous priors and in the second step, we sparsify the posterior through an efficient variant of the adaptive lasso, the signal adaptive variable selection (SAVS) algorithm. We propose a new variant of the SAVS which automates…

随机试验中的协变量调整：典范链接函数对模型误设的保护AI 解读

Covariate adjustment has the potential to increase power in the analysis of randomised trials, but mis-specification of the adjustment model could cause error. We explore what error is possible when the adjustment model omits a covariate by randomised treatment interaction, in a setting where the covariate is perfectly balanced between randomised treatments. We use mathematical arguments and analyses of single hypothetical data sets. We show that analysis by a generalised…

连续处理因果效应估计的端到端平衡方法AI 解读

We study the problem of observational causal inference with continuous treatments in the framework of inverse propensity-score weighting. To obtain stable weights, we design a new algorithm based on entropy balancing that learns weights to directly maximize causal inference accuracy using end-to-end optimization. In the process of optimization, these weights are automatically tuned to the specific dataset and causal inference algorithm being used. We provide a theoretical…

没有外生变异时反向因果关系的可检验性AI 解读

This paper shows that testability of reverse causality is possible even in the absence of exogenous variation, such as in the form of instrumental variables. Instead of relying on exogenous variation, we achieve testability by imposing relatively weak model restrictions and exploiting that a dependence of residual and purported cause is informative about the causal direction. Our main assumption is that the true functional relationship is nonlinear and that error terms are…

因果中介研究中的处理后混杂与敏感性分析AI 解读

In causal mediation studies that decompose an average treatment effect into a natural indirect effect (NIE) and a natural direct effect (NDE), examples of post-treatment confounding are abundant. Past research has generally considered it infeasible to adjust for a post-treatment confounder of the mediator-outcome relationship due to incomplete information: it is observed under the actual treatment condition while missing under the counterfactual treatment condition. This…

平衡性与样本量如何影响因果处理效应估计的偏差：一项模拟研究AI 解读

Observational studies are often used to understand relationships between exposures and outcomes. They do not, however, allow conclusions about causal relationships to be drawn unless statistical techniques are used to account for the imbalance of confounders across exposure groups. Propensity score and balance weighting (PSBW) are useful techniques that aim to reduce the imbalances between exposure groups by weighting the groups to look alike on the observed confounders.…

通过受控疫苗效力与受控风险评估免疫保护相关指标AI 解读

Immune correlates of protection (CoPs) are immunologic biomarkers accepted as a surrogate for an infectious disease clinical endpoint and thus can be used for traditional or provisional vaccine approval. To study CoPs in randomized, placebo-controlled trials, correlates of risk (CoRs) are first assessed in vaccine recipients. This analysis does not assess causation, as a CoR may fail to be a CoP. We propose a causal CoP analysis that estimates the controlled vaccine efficacy…

开发数字干预的微随机试验：实验设计与数据分析考量AI 解读

Just-in-time adaptive interventions (JITAIs) are time-varying adaptive interventions that use frequent opportunities for the intervention to be adapted--weekly, daily, or even many times a day. The micro-randomized trial (MRT) has emerged for use in informing the construction of JITAIs. MRTs can be used to address research questions about whether and under what circumstances JITAI components are effective, with the ultimate objective of developing effective and efficient…

网络引力模型：整合最大熵与计量经济学方法AI 解读

The World Trade Web (WTW) is the network of international trade relationships among world countries. Characterizing both the local link weights (observed trade volumes) and the global network structure (large-scale topology) of the WTW via a single model is still an open issue. While the traditional Gravity Model (GM) successfully replicates the observed trade volumes by employing macroeconomic properties such as GDP and geographic distance, it, unfortunately, predicts a…

因果推断的拓扑视角AI 解读

This paper presents a topological learning-theoretic perspective on causal inference by introducing a series of topologies defined on general spaces of structural causal models (SCMs). As an illustration of the framework we prove a topological causal hierarchy theorem, showing that substantive assumption-free causal inference is possible only in a meager set of SCMs. Thanks to a known correspondence between open sets in the weak topology and statistically verifiable…