每日简报

随机试验中二元结局个体化处理效应预测教程AI 解读

Randomized trials typically estimate average relative treatment effects, but decisions on the benefit of a treatment are possibly better informed by more individualized predictions of the absolute treatment effect. In case of a binary outcome, these predictions of absolute individualized treatment effect require knowledge of the individual's risk without treatment and incorporation of a possibly differential treatment effect (i.e. varying with patient characteristics). In…

线性回归中的污染偏差AI 解读

We study regressions with multiple treatments and a set of controls that is flexible enough to purge omitted variable bias. We show that these regressions generally fail to estimate convex averages of heterogeneous treatment effects -- instead, estimates of each treatment's effect are contaminated by non-convex averages of the effects of other treatments. We discuss three estimation approaches that avoid such contamination bias, including the targeting of easiest-to-estimate…

观察性研究倾向得分分析中的因果目标量选择AI 解读

Matching and weighting methods for observational studies involve the choice of an estimand, the causal effect with reference to a specific target population. Commonly used estimands include the average treatment effect in the treated (ATT), the average treatment effect in the untreated (ATU), the average treatment effect in the population (ATE), and the average treatment effect in the overlap (i.e., equipoise population; ATO). Each estimand has its own assumptions,…

受约束分类与政策学习AI 解读

Modern machine learning approaches to classification, including AdaBoost, support vector machines, and deep neural networks, utilize surrogate loss techniques to circumvent the computational complexity of minimizing empirical classification risk. These techniques are also useful for causal policy learning problems, since estimation of individualized treatment rules can be cast as a weighted (cost-sensitive) classification problem. Consistency of the surrogate loss approaches…

情境多臂老虎机实验后的统计推断AI 解读

Contextual bandit algorithms are increasingly replacing non-adaptive A/B tests in e-commerce, healthcare, and policymaking because they can both improve outcomes for study participants and increase the chance of identifying good or even best policies. To support credible inference on novel interventions at the end of the study, nonetheless, we still want to construct valid confidence intervals on average treatment effects, subgroup effects, or value of new policies. The…

疫情期间使用双向固定效应模型评估政策的局限AI 解读

In the context of the Covid-19 pandemic, multiple studies rely on two-way fixed effects (FE) models to assess the impact of mitigation policies on health outcomes. Building on the SIRD model of disease transmission, I show that FE models tend to be misspecified for three reasons. First, despite misleading common trends in the pre-treatment period, the parallel trends assumption generally does not hold. Second, heterogeneity in infection rates and infected populations across…

一般干预模式下面板处理效应的学习AI 解读

The problem of causal inference with panel data is a central econometric question. The following is a fundamental version of this problem: Let $M^*$ be a low rank matrix and $E$ be a zero-mean noise matrix. For a `treatment' matrix $Z$ with entries in $\{0,1\}$ we observe the matrix $O$ with entries $O_{ij} := M^*_{ij} + E_{ij} + \mathcal{T}_{ij} Z_{ij}$ where $\mathcal{T}_{ij} $ are unknown, heterogenous treatment effects. The problem requires we estimate the average…

利用机器学习推断处理特定生存曲线AI 解读

In the absence of data from a randomized trial, researchers often aim to use observational data to draw causal inference about the effect of a treatment on a time-to-event outcome. In this context, interest often focuses on the treatment-specific survival curves; that is, the survival curves were the entire population under study to be assigned to receive the treatment or not. Under certain causal conditions, including that all confounders of the treatment-outcome…

政策约束下最优动态处理分配规则的估计AI 解读

Many policies involve dynamics in their treatment assignments, where individuals receive sequential interventions over multiple stages. We study estimation of an optimal dynamic treatment regime that guides the optimal treatment assignment for each individual at each stage based on their history. We propose an empirical welfare maximization approach in this dynamic framework, which estimates the optimal dynamic treatment regime using data from an experimental or…

高维非参数因果结构学习AI 解读

The PC and FCI algorithms are popular constraint-based methods for learning the structure of directed acyclic graphs (DAGs) in the absence and presence of latent and selection variables, respectively. These algorithms (and their order-independent variants, PC-stable and FCI-stable) have been shown to be consistent for learning sparse high-dimensional DAGs based on partial correlations. However, inferring conditional independences from partial correlations is valid if the…

逆概率加权估计的自适应归一化AI 解读

Inverse probability weighting (IPW) is a general tool in survey sampling and causal inference, used both in Horvitz-Thompson estimators, which normalize by the sample size, and Hájek/self-normalized estimators, which normalize by the sum of the inverse probability weights. In this work we study a family of IPW estimators, first proposed by Trotter and Tukey in the context of Monte Carlo problems, that are normalized by an affine combination of these two terms. We show how…

回归不连续设计中的异质性处理效应发现AI 解读

The paper proposes a causal supervised machine learning algorithm to uncover treatment effect heterogeneity in sharp and fuzzy regression discontinuity (RD) designs. We develop a criterion for building an honest ``regression discontinuity tree'', where each leaf contains the RD estimate of a treatment conditional on the values of some pre-treatment covariates. It is a priori unknown which covariates are relevant for capturing treatment effect heterogeneity, and it is the…

因果效应的界及其在高维数据中的应用AI 解读

This paper addresses the problem of estimating causal effects when adjustment variables in the back-door or front-door criterion are partially observed. For such scenarios, we derive bounds on the causal effects by solving two non-linear optimization problems, and demonstrate that the bounds are sufficient. Using this optimization method, we propose a framework for dimensionality reduction that allows one to trade bias for estimation power, and demonstrate its performance…

线性因果模型中因果发现的不确定性推断AI 解读

Structural causal models postulate noisy functional relations among a set of interacting variables. The causal structure underlying each such model is naturally represented by a directed graph whose edges indicate for each variable which other variables it causally depends upon. Under a number of different model assumptions, it has been shown that this causal graph and, thus also, causal effects are identifiable from mere observational data. For these models, practical…

最大线性贝叶斯网络的马尔可夫等价性AI 解读

Max-linear Bayesian networks have emerged as highly applicable models for causal inference via extreme value data. However, conditional independence (CI) for max-linear Bayesian networks behaves differently than for classical Gaussian Bayesian networks. We establish the parallel between the two theories via tropicalization, and establish the surprising result that the Markov equivalence classes for max-linear Bayesian networks coincide with the ones obtained by regular CI.…

局部平均处理效应估计对单调性违背的敏感性AI 解读

In this paper, we develop a method to assess the sensitivity of local average treatment effect estimates to potential violations of the monotonicity assumption of Imbens and Angrist (1994). We parameterize the degree to which monotonicity is violated using two sensitivity parameters: the first one determines the share of defiers in the population, and the second one measures differences in the distributions of outcomes between compliers and defiers. For each pair of values…

因果聚合：基于约束的数据融合与联合干预效应推断AI 解读

In causal inference, it is common to estimate the causal effect of a single treatment variable on an outcome. However, practitioners may also be interested in the effect of simultaneous interventions on multiple covariates of a fixed target variable. We propose a novel method that allows to estimate the effect of joint interventions using data from different experiments in which only very few variables are manipulated. If there is only little randomized data or no randomized…

利用阶段树开展类别数据的情境特定因果发现AI 解读

Causal discovery algorithms aim at untangling complex causal relationships from data. Here, we study causal discovery and inference methods based on staged tree models, which can represent complex and asymmetric causal relationships between categorical variables. We provide a first graphical representation of the equivalence class of a staged tree, by looking only at a specific subset of its underlying independences. We further define a new pre-metric, inspired by the widely…

复杂原因的可操作化：中介分析的务实视角AI 解读

We examine the problem of causal response estimation for complex objects (e.g., text, images, genomics). In this setting, classical \emph{atomic} interventions are often not available (e.g., changes to characters, pixels, DNA base-pairs). Instead, we only have access to indirect or \emph{crude} interventions (e.g., enrolling in a writing program, modifying a scene, applying a gene therapy). In this work, we formalize this problem and provide an initial solution. Given a…

分配—控制图：因果推断研究设计的可视化辅助工具AI 解读

An important step for any causal inference study design is understanding the distribution of the treated and control subjects in terms of measured baseline covariates. However, not all baseline variation is equally important. In the observational context, balancing on baseline variation summarized in a propensity score can help reduce bias due to self-selection. In both observational and experimental studies, controlling baseline variation associated with the expected…

使用单调单指标多元自回归模型改进预测与网络估计AI 解读

Network estimation from multi-variate point process or time series data is a problem of fundamental importance. Prior work has focused on parametric approaches that require a known parametric model, which makes estimation procedures less robust to model mis-specification, non-linearities and heterogeneities. In this paper, we develop a semi-parametric approach based on the monotone single-index multi-variate autoregressive model (SIMAM) which addresses these challenges. We…

粗粒度结构嵌套均值模型的最优估计：HIV患者启动抗逆转录病毒治疗的应用AI 解读

Coarse structural nested mean models are used to estimate treatment effects from longitudinal observational data. Coarse structural nested mean models lead to a large class of estimators. It turns out that estimates and standard errors may differ considerably within this class. We prove that, under additional assumptions, there exists an explicit solution for the optimal estimator within the class of coarse structural nested mean models. Moreover, we show that even if the…

地理断点设计的稳健推断：评估警察辖区的影响AI 解读

We study variation in policing outcomes attributable to differential policing practices in New York City (NYC) using geographic regression discontinuity designs (GeoRDDs). By focusing on small geographic windows near police precinct boundaries we can estimate local average treatment effects of police precinct practices on arrest rates. We propose estimands and develop estimators for the GeoRDD when the data come from a spatial point process. Standard GeoRDDs rely on…

未知干扰结构下纵向数据的因果推断AI 解读

In longitudinal studies where units are embedded in space or a social network, interference may arise, meaning that a unit's outcome can depend on treatment histories of others. The presence of interference poses significant challenges for causal inference, particularly when the interference structure -- how a unit's outcome responds to others' influences -- is complex, heterogeneous, and unknown to researchers. This paper develops a general framework for identifying and…